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Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice

PloS one, 2016-10, Vol.11 (10), p.e0164094

2016

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Toxicology and Epidemiology: Improving the Science with a Framework for Combining Toxicological and Epidemiological Evidence to Establish Causal Inference

Toxicological sciences, 2011-08, Vol.122 (2), p.223-234

2011

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Pharmacokinetic, neurochemical, stereological and neuropathological studies on the potential effects of paraquat in the substantia nigra pars compacta and striatum of male C57BL/6J mice

Neurotoxicology (Park Forest South), 2013-07, Vol.37, p.1-14

2013

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Dietary administration of paraquat for 13weeks does not result in a loss of dopaminergic neurons in the substantia nigra of C57BL/6J mice

Regulatory toxicology and pharmacology, 2014-03, Vol.68 (2), p.250-258

2014

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Key challenges for toxicologists in the 21st century

Trends in pharmacological sciences (Regular ed.), 2001-06, Vol.22 (6), p.281-285

Smith, Lewis L

2001

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Dietary administration of paraquat for 13 weeks does not result in a loss of dopaminergic neurons in the substantia nigra of C57BL/6J mice

Regulatory toxicology and pharmacology, 2014-03, Vol.68 (2), p.250

2014

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Complexity meets development - a felicitous encounter on the road of life

Interdisciplinary description of complex systems, 2007-10, Vol.5 (2), p.151-160

Smith, L L

2007

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Tamoxifen DNA damage detected in human endometrium using accelerator mass spectrometry

Cancer research (Chicago, Ill.), 2003-12, Vol.63 (23), p.8461-8465

2003

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Tyrosinemia produced by 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione (NTBC) in experimental animals and its relationship to corneal injury

Toxicology and applied pharmacology, 2006-08, Vol.215 (1), p.9-16

2006

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Chemoprevention of Breast Cancer by Tamoxifen: Risks and Opportunities

Critical reviews in toxicology, 2000-01, Vol.30 (5), p.571-594

2000

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Use of Genomics in Toxicology and Epidemiology: Findings and Recommendations of a Workshop

Environmental health perspectives, 2002-10, Vol.110 (10), p.1047-1050

2002

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Predicting Future Human and Environmental Health Challenges: The Health and Environmental Sciences Institute's Scientific Mapping Exercise

Critical reviews in toxicology, 2008-01, Vol.38 (10), p.817-845

2008

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Tamoxifen causes gene mutations in the livers of Lambda/lacI transgenic rats

Cancer research (Chicago, Ill.), 1997-04, Vol.57 (7), p.1288-1293

1997

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The role of mode of action studies in extrapolating to human risks in toxicology

Toxicology Letters, 2003-04, Vol.140, p.317-322

2003

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Tamoxifen induces G:C→T:A mutations in the cII gene in the liver of lambda/lacI transgenic rats but not at 5′-CpG-3′ dinucleotide sequences as found in the lacI transgene

Carcinogenesis (New York), 1999-07, Vol.20 (7), p.1351-1356

1999

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Tissue distribution of 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione (NTBC) and its effect on enzymes involved in tyrosine catabolism in the mouse

Toxicology (Amsterdam), 2000-04, Vol.144 (1), p.179-187

2000

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Tamoxifen induces short-term cumulative DNA damage and liver tumors in rats : promotion by phenobarbital

Cancer research (Chicago, Ill.), 1995-02, Vol.55 (3), p.544-547

1995

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Comparative Hazards of Chrysotile Asbestos and Its Substitutes: A European Perspective

Environmental health perspectives, 1999-08, Vol.107 (8), p.607-611

1999

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Short-term dosing of α-hydroxytamoxifen results in DNA damage but does not lead to liver tumours in female Wistar/Han rats

Carcinogenesis (New York), 2001-04, Vol.22 (4), p.553-557

2001

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Economies and Markets as Complex Systems: LOOKING AT THEM THIS WAY MAY PROVIDE FRESH INSIGHT

Business economics (Cleveland, Ohio), 2002-01, Vol.37 (1), p.46-53

Smith, Lewis L.

2002

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Species differences in the covalent binding of [ 14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved

Biochemical pharmacology, 1995-04, Vol.49 (8), p.1035-1042

1995

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Tamoxifen mutagenesis and carcinogenesis in livers of lambda/ lacI transgenic rats: selective influence of phenobarbital promotion

Cancer letters, 2001-01, Vol.162 (1), p.117-122

2001

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Determination of DNA Damage in F344 Rats Induced by Geometric Isomers of Tamoxifen and Analogues

Chemical research in toxicology, 1998-05, Vol.11 (5), p.527-534

1998

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Future challenges for toxicologists

Toxicology letters, 2006-09, Vol.164, p.S38-S39

Smith, Lewis L.

2006

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Tissue Distribution of 2-(2-Nitro-4-trifluoromethylbenzoyl)cyclohexane-1,3-dione (NTBC): Effect on Enzymes Involved in Tyrosine Catabolism and Relevance to Ocular Toxicity in the Rat

Toxicology and applied pharmacology, 1996-12, Vol.141 (2), p.439-447

1996

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Assessment of the Effects of MPTP and Paraquat on Dopaminergic Neurons and Microglia in the Substantia Nigra Pars Compacta of C57BL/6 Mice

Toxicology and Epidemiology: Improving the Science with a Framework for Combining Toxicological and Epidemiological Evidence to Establish Causal Inference

Pharmacokinetic, neurochemical, stereological and neuropathological studies on the potential effects of paraquat in the substantia nigra pars compacta and striatum of male C57BL/6J mice

Dietary administration of paraquat for 13weeks does not result in a loss of dopaminergic neurons in the substantia nigra of C57BL/6J mice

Key challenges for toxicologists in the 21st century

Dietary administration of paraquat for 13 weeks does not result in a loss of dopaminergic neurons in the substantia nigra of C57BL/6J mice

Complexity meets development - a felicitous encounter on the road of life

Tamoxifen DNA damage detected in human endometrium using accelerator mass spectrometry

Tyrosinemia produced by 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione (NTBC) in experimental animals and its relationship to corneal injury

Chemoprevention of Breast Cancer by Tamoxifen: Risks and Opportunities

Use of Genomics in Toxicology and Epidemiology: Findings and Recommendations of a Workshop

Predicting Future Human and Environmental Health Challenges: The Health and Environmental Sciences Institute's Scientific Mapping Exercise

Tamoxifen causes gene mutations in the livers of Lambda/lacI transgenic rats

The role of mode of action studies in extrapolating to human risks in toxicology

Tamoxifen induces G:C→T:A mutations in the cII gene in the liver of lambda/lacI transgenic rats but not at 5′-CpG-3′ dinucleotide sequences as found in the lacI transgene

Tissue distribution of 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione (NTBC) and its effect on enzymes involved in tyrosine catabolism in the mouse

Tamoxifen induces short-term cumulative DNA damage and liver tumors in rats : promotion by phenobarbital

Comparative Hazards of Chrysotile Asbestos and Its Substitutes: A European Perspective

Short-term dosing of α-hydroxytamoxifen results in DNA damage but does not lead to liver tumours in female Wistar/Han rats

Economies and Markets as Complex Systems: LOOKING AT THEM THIS WAY MAY PROVIDE FRESH INSIGHT

Species differences in the covalent binding of [ 14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved

Tamoxifen mutagenesis and carcinogenesis in livers of lambda/ lacI transgenic rats: selective influence of phenobarbital promotion

Determination of DNA Damage in F344 Rats Induced by Geometric Isomers of Tamoxifen and Analogues

Future challenges for toxicologists

Tissue Distribution of 2-(2-Nitro-4-trifluoromethylbenzoyl)cyclohexane-1,3-dione (NTBC): Effect on Enzymes Involved in Tyrosine Catabolism and Relevance to Ocular Toxicity in the Rat

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