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Type I IFNs drive hematopoietic stem and progenitor cell collapse via impaired proliferation and increased RIPK1-dependent cell death during shock-like ehrlichial infection

PLoS pathogens, 2018-08, Vol.14 (8), p.e1007234-e1007234

2018

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Concise Review: Current Concepts in Bone Marrow Microenvironmental Regulation of Hematopoietic Stem and Progenitor Cells

Stem cells (Dayton, Ohio), 2013-06, Vol.31 (6), p.1044-1050

2013

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CCR5 maintains macrophages in the bone marrow and drives hematopoietic failure in a mouse model of severe aplastic anemia

Leukemia, 2021-11, Vol.35 (11), p.3139-3151

2021

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Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression

Haematologica (Roma), 2018-09, Vol.103 (9), p.1451-1461

2018

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Hematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic Anemia

Frontiers in immunology, 2016-08, Vol.7, p.330-330

2016

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15-PGDH regulates hematopoietic and gastrointestinal fitness during aging

PloS one, 2022-05, Vol.17 (5), p.e0268787-e0268787

2022

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Therapeutic targeting of 15-PGDH in murine pulmonary fibrosis

Scientific reports, 2020-07, Vol.10 (1), p.11657, Article 11657

2020

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Machine learning predicts cancer subtypes and progression from blood immune signatures

PloS one, 2022-02, Vol.17 (2), p.e0264631

2022

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Sex-dependent niche responses modulate steady-state and regenerative hematopoiesis

Experimental hematology, 2024-09, Vol.137, p.104247, Article 104247

2024

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IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock

Stem cell reports, 2021-12, Vol.16 (12), p.2887-2899

2021

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Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells

Blood, 2012-03, Vol.119 (11), p.2489-2499

2012

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15-PGDH Inhibition Mitigates Aplastic Anemia Severity

Blood, 2019-11, Vol.134 (Supplement_1), p.1220-1220

2019

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Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy

Current gene therapy, 2011-02, Vol.11 (1), p.11-27

2011

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Single-Shot ChAd3-MARV Vaccine in Modified Formulation Buffer Shows 100% Protection of NHPs

Vaccines (Basel), 2022-11, Vol.10 (11), p.1935

2022

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Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia

Nature communications, 2022-04, Vol.13 (1), p.2227-2227, Article 2227

2022

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Type I interferons drive hematopoietic progenitor cell depletion via necroptosis in a model of severe rickettsial infection

Experimental hematology, 2016-09, Vol.44 (9), p.S100-S100

2016

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Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

Nature communications, 2022-04, Vol.13 (1), p.2228-2228, Article 2228

2022

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“I’m not gonna be another statistic”: The imagined futures of former foster youth

American journal of cultural sociology, 2017-03, Vol.5 (1-2), p.154-180

Smith, Julianne M.

2017

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Polymer Microparticles Prolong Delivery of the 15-PGDH Inhibitor SW033291

Pharmaceutics, 2021-12, Vol.14 (1), p.85

2021

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Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

Nucleic acids research, 2009-09, Vol.37 (16), p.5405-5419

2009

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15-PGDH inhibition activates the splenic niche to promote hematopoietic regeneration

JCI insight, 2021-03, Vol.6 (6)

2021

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A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

Nucleic acids research, 2006-12, Vol.34 (22), p.e149-e149

2006

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Osteoblastic VEGF Coordinates Remodeling of the Hematopoietic Stem Cell Niche

Blood, 2014-12, Vol.124 (21), p.772-772

2014

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Type I IFNs drive hematopoietic stem and progenitor cell collapse via impaired proliferation and increased RIPK1-dependent cell death during shock-like ehrlichial infection

Concise Review: Current Concepts in Bone Marrow Microenvironmental Regulation of Hematopoietic Stem and Progenitor Cells

CCR5 maintains macrophages in the bone marrow and drives hematopoietic failure in a mouse model of severe aplastic anemia

Hematopoietic stem cell loss and hematopoietic failure in severe aplastic anemia is driven by macrophages and aberrant podoplanin expression

Hematopoietic Stem Cell Regulation by Type I and II Interferons in the Pathogenesis of Acquired Aplastic Anemia

15-PGDH regulates hematopoietic and gastrointestinal fitness during aging

Therapeutic targeting of 15-PGDH in murine pulmonary fibrosis

Machine learning predicts cancer subtypes and progression from blood immune signatures

Sex-dependent niche responses modulate steady-state and regenerative hematopoiesis

IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock

Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells

15-PGDH Inhibition Mitigates Aplastic Anemia Severity

Aged marrow macrophages expand platelet-biased hematopoietic stem cells via interleukin-1B

Meganucleases and other tools for targeted genome engineering: perspectives and challenges for gene therapy

Single-Shot ChAd3-MARV Vaccine in Modified Formulation Buffer Shows 100% Protection of NHPs

Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia

Type I interferons drive hematopoietic progenitor cell depletion via necroptosis in a model of severe rickettsial infection

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells

“I’m not gonna be another statistic”: The imagined futures of former foster youth

Polymer Microparticles Prolong Delivery of the 15-PGDH Inhibitor SW033291

Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

15-PGDH inhibition activates the splenic niche to promote hematopoietic regeneration

A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences

Efficacy Proof of Concept for Allogeneic CD123 Targeting CAR T-Cells Against Primary Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Efficient Control of Tumor Progression in PDX Model and Potential Loss of CD123 Expression in Relapsed Disease

Osteoblastic VEGF Coordinates Remodeling of the Hematopoietic Stem Cell Niche

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