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P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study

The Lancet (British edition), 2015-03, Vol.385 (9974), p.1198-1205

2015

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Performance of a digital signal processing algorithm for the accurate quantification of cough frequency

The European respiratory journal, 2021-08, Vol.58 (2), p.2004271

2021

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How often do healthy people cough?

Respiratory research, 2023-11, Vol.24 (1), p.275-275, Article 275

2023

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Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

The European respiratory journal, 2014-11, Vol.44 (5), p.1132-1148

2014

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Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: Role of adenosine triphosphate

Journal of allergy and clinical immunology, 2016-07, Vol.138 (1), p.249-261.e12

2016

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Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction

Journal of allergy and clinical immunology, 2017-03, Vol.139 (3), p.771-779.e10

2017

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A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response

The European respiratory journal, 2014-11, Vol.44 (5), p.1149-1155

2014

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Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: A double-blind randomized controlled trial

Journal of allergy and clinical immunology, 2014-07, Vol.134 (1), p.56-62.e4

2014

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Objective Cough Frequency, Airway Inflammation, and Disease Control in Asthma

Chest, 2016-06, Vol.149 (6), p.1460-1466

2016

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The interaction between bronchoconstriction and cough in asthma

Thorax, 2017-12, Vol.72 (12), p.1144-1146

2017

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Morphologic Characterization of Nerves in Whole-Mount Airway Biopsies

American journal of respiratory and critical care medicine, 2015-07, Vol.192 (1), p.30-39

2015

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An observational study to understand burden and cost of care in adults diagnosed with refractory chronic cough (RCC) or unexplained chronic cough (UCC)

Respiratory research, 2024-07, Vol.25 (1), p.265-9, Article 265

2024

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Chest wall dynamics during voluntary and induced cough in healthy volunteers

The Journal of physiology, 2012-02, Vol.590 (3), p.563-574

2012

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Acoustic Cough—Reflux Associations in Chronic Cough: Potential Triggers and Mechanisms

Gastroenterology (New York, N.Y. 1943), 2010-09, Vol.139 (3), p.754-762

2010

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Predictors of Objective Cough Frequency in Chronic Obstructive Pulmonary Disease

American journal of respiratory and critical care medicine, 2013-05, Vol.187 (9), p.943-949

2013

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A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough

Lung, 2023-02, Vol.201 (1), p.25-35

2023

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Chronic Cough

The New England journal of medicine, 2016-10, Vol.375 (16), p.1544-1551

2016

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Addressing unmet needs in understanding asthma mechanisms

The European respiratory journal, 2017-05, Vol.49 (5), p.1602448-1602448

2017

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The Effect of Aclidinium on Symptoms Including Cough in Chronic Obstructive Pulmonary Disease: A Phase 4, Double-Blind, Placebo-controlled, Parallel-Group Study

American journal of respiratory and critical care medicine, 2019-09, Vol.200 (5), p.642-645

2019

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Pharmacodynamic modeling of cough responses to capsaicin inhalation calls into question the utility of the C5 end point

Journal of allergy and clinical immunology, 2013-10, Vol.132 (4), p.847-855.e5

2013

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The Therapeutic Landscape in Chronic Cough

Lung, 2024-02, Vol.202 (1), p.5-16

Smith, Jaclyn A.

2024

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Design and rationale of two phase 3 randomised controlled trials (COUGH-1 and COUGH-2) of gefapixant, a P2X3 receptor antagonist, in refractory or unexplained chronic cough

ERJ open research, 2020-10, Vol.6 (4), p.284

2020

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A Novel Approach to Studying the Relationship Between Subjective and Objective Measures of Cough

Chest, 2011-03, Vol.139 (3), p.569-575

2011

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Chronic cough is associated with increased reporting of autonomic symptoms

ERJ open research, 2021-07, Vol.7 (3), p.105

2021

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A comparison of objective and subjective measures of cough in asthma

Journal of allergy and clinical immunology, 2008-11, Vol.122 (5), p.903-907

2008

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P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study

Performance of a digital signal processing algorithm for the accurate quantification of cough frequency

How often do healthy people cough?

Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: Role of adenosine triphosphate

Capsaicin-evoked cough responses in asthmatic patients: Evidence for airway neuronal dysfunction

A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response

Transient receptor potential vanilloid 1 (TRPV1) antagonism in patients with refractory chronic cough: A double-blind randomized controlled trial

Objective Cough Frequency, Airway Inflammation, and Disease Control in Asthma

The interaction between bronchoconstriction and cough in asthma

Morphologic Characterization of Nerves in Whole-Mount Airway Biopsies

An observational study to understand burden and cost of care in adults diagnosed with refractory chronic cough (RCC) or unexplained chronic cough (UCC)

Chest wall dynamics during voluntary and induced cough in healthy volunteers

Acoustic Cough—Reflux Associations in Chronic Cough: Potential Triggers and Mechanisms

Predictors of Objective Cough Frequency in Chronic Obstructive Pulmonary Disease

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough

Chronic Cough

Addressing unmet needs in understanding asthma mechanisms

The Effect of Aclidinium on Symptoms Including Cough in Chronic Obstructive Pulmonary Disease: A Phase 4, Double-Blind, Placebo-controlled, Parallel-Group Study

Pharmacodynamic modeling of cough responses to capsaicin inhalation calls into question the utility of the C5 end point

The Therapeutic Landscape in Chronic Cough

Design and rationale of two phase 3 randomised controlled trials (COUGH-1 and COUGH-2) of gefapixant, a P2X3 receptor antagonist, in refractory or unexplained chronic cough

A Novel Approach to Studying the Relationship Between Subjective and Objective Measures of Cough

Chronic cough is associated with increased reporting of autonomic symptoms

A comparison of objective and subjective measures of cough in asthma

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