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Modeling of the time-dependency of in vitro drug cytotoxicity and resistance

Cancer research (Chicago, Ill.), 1998-12, Vol.58 (24), p.5749-5761

1998

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MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors

The American journal of pathology, 1996-09, Vol.149 (3), p.853-858

1996

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S-phase modulation by irinotecan : pilot studies in advanced solid tumors

Cancer chemotherapy and pharmacology, 2005-11, Vol.56 (5), p.447-454

2005

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HsMCM2/BM28: a novel proliferation marker for human tumors and normal tissues

Laboratory investigation, 1998-01, Vol.78 (1), p.73

1998

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P-glycoprotein in human sarcoma: evidence for multidrug resistance

Journal of clinical oncology, 1987-09, Vol.5 (9), p.1452-1460

1987

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Super in vitro synergy between inhibitors of dihydrofolate reductase and inhibitors of other folate-requiring enzymes: The critical role of polyglutamylation

Cancer research (Chicago, Ill.), 1998-07, Vol.58 (14), p.3036-3050

1998

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New immunohistochemical "sandwich" staining method for mdr1 P- glycoprotein detection with JSB-1 monoclonal antibody in formalin- fixed, paraffin-embedded human tissues

The American journal of pathology, 1994-02, Vol.144 (2), p.227-236

1994

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Persistent Induction of Apoptosis and Suppression of Mitosis as the Basis for Curative Therapy with S-1, an Oral 5-Fluorouracil Prodrug in a Colorectal Tumor Model

Clinical cancer research, 1999-02, Vol.5 (2), p.267-274

1999

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Involvement of cyclin d1‐cdk5 overexpression and mcm3 cleavage in bax‐associated spontaneous apoptosis and differentiation in an a253 human head and neck carcinoma xenograft model

International journal of cancer, 1999-10, Vol.83 (3), p.341-348

1999

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Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-Amino-4-oxo-4,6,7,8-tetrahydro-3 H-pyrimidino[5,4,6][1,4]thiazin-6-yl)-( S)-ethyl]-2,5-thienoylamino- l-glutamic acid (AG2034) : Comparison across sensitive and resistant human tumor cell lines

Biochemical pharmacology, 1999-03, Vol.57 (5), p.567-577

1999

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Combined action of paclitaxel and cisplatin against wildtype and resistant human ovarian carcinoma cells

Cancer chemotherapy and pharmacology, 1997, Vol.40 (6), p.495-505

1997

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Inhibition of Implantation of Murine Bladder Tumor by Thiotepa in Cauterized Bladder

The Journal of urology, 1989-12, Vol.142 (6), p.1589-1593

1989

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Mechanisms of acquired resistance to modulation of 5-fluorouracil by leucovorin in HCT-8 human ileocecal carcinoma cells

Biochemical pharmacology, 1997-03, Vol.53 (5), p.689-696

1997

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Comparison of an immunoperoxidase "sandwich" staining method and western blot detection of P-glycoprotein in human cell lines and sarcomas

The American journal of pathology, 1992-05, Vol.140 (5), p.1009-1016

1992

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Cellular heterogeneity in DNA damage and growth inhibition induced by ICI D1694, thymidylate synthase inhibitor, using single cell assays

Biochemical pharmacology, 1994-08, Vol.48 (5), p.997-1002

1994

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Assessment of Human Genitourinary Tumors and Chemosensitivity Testing In 3-Dimensional Collagen Gel Culture

The Journal of urology, 1990-05, Vol.143 (5), p.1041-1045

1990

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Characterization of tumor cell heterogeneity of a murine leukemia cell line (L1210) in response to arabinosylcytosine : quantitation using a computerized image analysis system

Experimental hematology, 1993-05, Vol.21 (5), p.602-607

1993

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Prevention of Quinone-Mediated DNA Arylation by Antioxidants

Biochemical and biophysical research communications, 1999-09, Vol.262 (3), p.769-774

1999

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Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine

Biochemical pharmacology, 1993-03, Vol.45 (5), p.1157-1164

1993

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Growth slow-down and growth arrest of human colon carcinoma cells HCT-8 in vitro after exposure to 5-fluoro-2′-deoxyuridine

Cell proliferation, 1993-05, Vol.26 (3), p.291-303

1993

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Characterization of Protein Kinase chk1 Essential for the Cell Cycle Checkpoint after Exposure of Human Head and Neck Carcinoma A253 Cells to a Novel Topoisomerase I Inhibitor BNP1350

Molecular pharmacology, 2000-03, Vol.57 (3), p.453-459

2000

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Effect of doxorubicin, daunorubicin, and idarubicin on the growth rate of human leukemia cells (K562) studied with image analysis

Leukemia, 1993-06, Vol.7 (6), p.872

1993

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Growth of Human Renal Cortical Tissue on Collagen Gel

In Vitro Cellular & Developmental Biology - Animal, 1992-02, Vol.28A (2), p.128-135

1992

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Glucose Consumption End Point in Primary Histoculture Indicates Recovery of Human Tumors from Drug Treatment

In Vitro Cellular & Developmental Biology - Animal, 1992-09, Vol.28A (9/10), p.585-587

1992

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Cyclin E–Cdk2 Activation Is Associated with Cell Cycle Arrest and Inhibition of DNA Replication Induced by the Thymidylate Synthase Inhibitor Tomudex

Experimental cell research, 1999-02, Vol.247 (1), p.189-199

1999

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Modeling of the time-dependency of in vitro drug cytotoxicity and resistance

MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors

S-phase modulation by irinotecan : pilot studies in advanced solid tumors

HsMCM2/BM28: a novel proliferation marker for human tumors and normal tissues

P-glycoprotein in human sarcoma: evidence for multidrug resistance

Super in vitro synergy between inhibitors of dihydrofolate reductase and inhibitors of other folate-requiring enzymes: The critical role of polyglutamylation

New immunohistochemical "sandwich" staining method for mdr1 P- glycoprotein detection with JSB-1 monoclonal antibody in formalin- fixed, paraffin-embedded human tissues

Persistent Induction of Apoptosis and Suppression of Mitosis as the Basis for Curative Therapy with S-1, an Oral 5-Fluorouracil Prodrug in a Colorectal Tumor Model

Involvement of cyclin d1‐cdk5 overexpression and mcm3 cleavage in bax‐associated spontaneous apoptosis and differentiation in an a253 human head and neck carcinoma xenograft model

Combined action of paclitaxel and cisplatin against wildtype and resistant human ovarian carcinoma cells

Inhibition of Implantation of Murine Bladder Tumor by Thiotepa in Cauterized Bladder

Mechanisms of acquired resistance to modulation of 5-fluorouracil by leucovorin in HCT-8 human ileocecal carcinoma cells

Comparison of an immunoperoxidase "sandwich" staining method and western blot detection of P-glycoprotein in human cell lines and sarcomas

Cellular heterogeneity in DNA damage and growth inhibition induced by ICI D1694, thymidylate synthase inhibitor, using single cell assays

Assessment of Human Genitourinary Tumors and Chemosensitivity Testing In 3-Dimensional Collagen Gel Culture

Characterization of tumor cell heterogeneity of a murine leukemia cell line (L1210) in response to arabinosylcytosine : quantitation using a computerized image analysis system

Prevention of Quinone-Mediated DNA Arylation by Antioxidants

Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine

Growth slow-down and growth arrest of human colon carcinoma cells HCT-8 in vitro after exposure to 5-fluoro-2′-deoxyuridine

Characterization of Protein Kinase chk1 Essential for the Cell Cycle Checkpoint after Exposure of Human Head and Neck Carcinoma A253 Cells to a Novel Topoisomerase I Inhibitor BNP1350

Effect of doxorubicin, daunorubicin, and idarubicin on the growth rate of human leukemia cells (K562) studied with image analysis

Growth of Human Renal Cortical Tissue on Collagen Gel

Glucose Consumption End Point in Primary Histoculture Indicates Recovery of Human Tumors from Drug Treatment

Cyclin E–Cdk2 Activation Is Associated with Cell Cycle Arrest and Inhibition of DNA Replication Induced by the Thymidylate Synthase Inhibitor Tomudex

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