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Gene Transfer in Humans Using a Conditionally Replicating Lentiviral Vector

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (46), p.17372-17377

2006

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On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes

Biochimica et biophysica acta, 2001-11, Vol.1515 (1), p.23-37

2001

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Efficient clinical-grade γ-retroviral vector purification by high-speed centrifugation for CAR T cell manufacturing

Molecular therapy. Methods & clinical development, 2023-03, Vol.28, p.116-128

2023

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Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect

The Journal of clinical investigation, 1999-12, Vol.104 (11), p.R55-R62

1999

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Sterically Stabilized pH-sensitive Liposomes, INTRACELLULAR DELIVERY OF AQUEOUS CONTENTS AND PROLONGED CIRCULATION IN VIVO

The Journal of biological chemistry, 1997-01, Vol.272 (4), p.2382-2388

1997

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Gene delivery mediated by cationic liposomes: from biophysical aspects to enhancement of transfection

Molecular membrane biology, 1999, Vol.16 (1), p.103-109

1999

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Transfection of human macrophages by lipoplexes via the combined use of transferrin and pH-sensitive peptides

Journal of leukocyte biology, 1999-02, Vol.65 (2), p.270-279

1999

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Infection of Human Airway Epithelia with H1N1, H2N2, and H3N2 Influenza A Virus Strains

Molecular therapy, 2001-03, Vol.3 (3), p.395-402

2001

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Influence of Cell Polarity on Retrovirus-Mediated Gene Transfer to Differentiated Human Airway Epithelia

Journal of Virology, 1998-12, Vol.72 (12), p.9818-9826

1998

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Delivery of an anti-HIV-1 ribozyme into HIV-infected cells via cationic liposomes

Biochimica et biophysica acta, 1998-06, Vol.1372 (1), p.55-68

1998

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Liposome-mediated delivery of antiviral agents to human immunodeficiency virus-infected cells

Molecular membrane biology, 1999, Vol.16 (1), p.111-118

Nejat Duzgunes, Elizabeth Pretzer, Sergio Simoes, Vladimir Slepushkin, Krystyna Konopka, Diana Flasher, Maria C. Pedroso de Lima

1999

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Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum

Biochimica et biophysica acta, 2000-02, Vol.1463 (2), p.459-469

2000

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Efficient Lentiviral Vector-mediated Control of HIV-1 Replication in CD4 Lymphocytes from Diverse HIV Infected Patients Grouped According to CD4 Count and Viral Load

Molecular therapy, 2004-06, Vol.9 (6), p.902-913

2004

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Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol

The journal of gene medicine, 2004-09, Vol.6 (9), p.963-973

2004

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Gene therapy for Hunter syndrome: Prevention of neurocognitive deficit in MPS II mice by engraftment with lentiviral vector-transduced hematopoietic stem cells (HSC) but not with wild type HSC

Molecular genetics and metabolism, 2013-02, Vol.108 (2), p.S64-S64

2013

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Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector

The journal of gene medicine, 2005-06, Vol.7 (6), p.818-834

2005

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Manufacturing considerations underpinning viral & non-viral platform selection

Cell and Gene Therapy Insights, 2022-12, Vol.8 (11), p.1497-1497

2022

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Manufacturing considerations underpinning viral and non-viral platform selection

Cell and Gene Therapy Insights, 2022-08, Vol.8 (6), p.733-743

2022

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Protection of mice against influenza A virus challenge by vaccination with baculovirus-expressed M2 protein

Vaccine, 1995, Vol.13 (15), p.1399-1402

1995

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Genetically engineered lymphocytes in metastatic melanoma: TIL 1383I TCR transduced T-cells are detectable after infusion

Journal for immunotherapy of cancer, 2013-11, Vol.1 (S1), p.P31-P31, Article P31

2013

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Sterically Stabilized pH-Sensitive Liposomes

Methods in Enzymology, 2004, Vol.387, p.134-147

2004

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Keratinocyte growth factor induced epithelial proliferation facilitates retroviral-mediated gene transfer to distal lung epithelia in vivo

The journal of gene medicine, 1999-01, Vol.1 (1), p.22-30

1999

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755. Phase II Clinical Trial Demonstrates the Safety and Tolerability of Multiple Doses of Autologous CD4+ T Cells Transduced with VRX496, a Lentiviral Vector Delivering Anti-HIV Antisense in Patients Failing 1 or More HAART Treatment

Molecular therapy, 2006-05, Vol.13 (S1), p.S292-S292

2006

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Inhibition of Simian/Human Immunodeficiency Virus Replication in CD4 T Cells Derived from Lentiviral-Transduced CD34 Hematopoietic Cells

Molecular therapy, 2005-12, Vol.12 (6), p.1157-1167

2005

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Gene Transfer in Humans Using a Conditionally Replicating Lentiviral Vector

On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes

Efficient clinical-grade γ-retroviral vector purification by high-speed centrifugation for CAR T cell manufacturing

Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect

Sterically Stabilized pH-sensitive Liposomes, INTRACELLULAR DELIVERY OF AQUEOUS CONTENTS AND PROLONGED CIRCULATION IN VIVO

Gene delivery mediated by cationic liposomes: from biophysical aspects to enhancement of transfection

Transfection of human macrophages by lipoplexes via the combined use of transferrin and pH-sensitive peptides

Infection of Human Airway Epithelia with H1N1, H2N2, and H3N2 Influenza A Virus Strains

Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIV

Influence of Cell Polarity on Retrovirus-Mediated Gene Transfer to Differentiated Human Airway Epithelia

Delivery of an anti-HIV-1 ribozyme into HIV-infected cells via cationic liposomes

Liposome-mediated delivery of antiviral agents to human immunodeficiency virus-infected cells

Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum

Efficient Lentiviral Vector-mediated Control of HIV-1 Replication in CD4 Lymphocytes from Diverse HIV Infected Patients Grouped According to CD4 Count and Viral Load

Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol

Gene therapy for Hunter syndrome: Prevention of neurocognitive deficit in MPS II mice by engraftment with lentiviral vector-transduced hematopoietic stem cells (HSC) but not with wild type HSC

Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector

Manufacturing considerations underpinning viral & non-viral platform selection

Manufacturing considerations underpinning viral and non-viral platform selection

Protection of mice against influenza A virus challenge by vaccination with baculovirus-expressed M2 protein

Genetically engineered lymphocytes in metastatic melanoma: TIL 1383I TCR transduced T-cells are detectable after infusion

Sterically Stabilized pH-Sensitive Liposomes

Keratinocyte growth factor induced epithelial proliferation facilitates retroviral-mediated gene transfer to distal lung epithelia in vivo

755. Phase II Clinical Trial Demonstrates the Safety and Tolerability of Multiple Doses of Autologous CD4+ T Cells Transduced with VRX496, a Lentiviral Vector Delivering Anti-HIV Antisense in Patients Failing 1 or More HAART Treatment

Inhibition of Simian/Human Immunodeficiency Virus Replication in CD4 T Cells Derived from Lentiviral-Transduced CD34 Hematopoietic Cells

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