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The B-Cell Follicle in HIV Infection: Barrier to a Cure

Frontiers in immunology, 2018-01, Vol.9, p.20-20

2018

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CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection

PLoS pathogens, 2022-02, Vol.18 (2), p.e1009831-e1009831

2022

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Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL

The Journal of immunology (1950), 2014-12, Vol.193 (11), p.5613-5625

2014

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Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection

PLoS pathogens, 2016-10, Vol.12 (10), p.e1005924

2016

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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

PLoS pathogens, 2020-03, Vol.16 (3), p.e1008339-e1008339

2020

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Detection of Antigen-Specific T Cells Using In Situ MHC Tetramer Staining

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5165

2019

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Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication

Frontiers in immunology, 2018-03, Vol.9, p.492-492

2018

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Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection

PLoS pathogens, 2019-03, Vol.15 (3), p.e1007311

2019

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Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques

PLoS computational biology, 2018-10, Vol.14 (10), p.e1006461-e1006461

2018

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Development of an anti-CAR antibody response in SIV-infected rhesus macaques treated with CD4-MBL CAR/CXCR5 T cells

Frontiers in immunology, 2022-12, Vol.13, p.1032537-1032537

2022

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Visualizing Antigen-Specific and Infected Cells in Situ Predicts Outcomes in Early Viral Infection

Science (American Association for the Advancement of Science), 2009-03, Vol.323 (5922), p.1726-1729

2009

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Assessment of anti-CD20 antibody pre-treatment for augmentation of CAR-T cell therapy in SIV-infected rhesus macaques

Frontiers in immunology, 2023-02, Vol.14, p.1101446-1101446

2023

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CTL Fail to Accumulate at Sites of HIV-1 Replication in Lymphoid Tissue

Journal of Immunology, 2007-06, Vol.178 (11), p.6975-6983

2007

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Antigenic cells augment CAR T cells

Blood, 2020-10, Vol.136 (15), p.1701-1702

Skinner, Pamela J.

2020

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Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations

Molecular therapy. Methods & clinical development, 2020-03, Vol.16, p.1-10

2020

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The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cell follicles

Blood advances, 2018-01, Vol.2 (2), p.76-84

2018

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In Situ Peptide-MHC-II Tetramer Staining of Antigen-Specific CD4+ T Cells in Tissues

PloS one, 2015-06, Vol.10 (6), p.e0128862-e0128862

2015

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Treatment of Prion Disease with Heterologous Prion Proteins

PloS one, 2015-07, Vol.10 (7), p.e0131993-e0131993

2015

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Location and dynamics of the immunodominant CD8 T cell response to SIVΔnef immunization and SIVmac251 vaginal challenge

PloS one, 2013-12, Vol.8 (12), p.e81623

2013

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CD8+ T-Lymphocyte Response to Major Immunodominant Epitopes after Vaginal Exposure to Simian Immunodeficiency Virus: Too Late and Too Little

Journal of Virology, 2005-07, Vol.79 (14), p.9228-9235

2005

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With Minimal Systemic T-Cell Expansion, CD8+ T Cells Mediate Protection of Rhesus Macaques Immunized with Attenuated Simian-Human Immunodeficiency Virus SHIV89.6 from Vaginal Challenge with Simian Immunodeficiency Virus

Journal of Virology, 2008-11, Vol.82 (22), p.11181-11196

2008

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Gene expression alterations in brains of mice infected with three strains of scrapie

BMC genomics, 2006-05, Vol.7 (1), p.114-114, Article 114

2006

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Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (8), p.1976-1981

2017

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Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8+ Cells In Vivo

Journal of virology, 2016-12, Vol.90 (24), p.11168-11180

2016

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Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection

Nature communications, 2015-10, Vol.6 (1), p.8608-8608, Article 8608

2015

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The B-Cell Follicle in HIV Infection: Barrier to a Cure

CAR/CXCR5-T cell immunotherapy is safe and potentially efficacious in promoting sustained remission of SIV infection

Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL

Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

Detection of Antigen-Specific T Cells Using In Situ MHC Tetramer Staining

Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication

Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection

Virus and CTL dynamics in the extrafollicular and follicular tissue compartments in SIV-infected macaques

Development of an anti-CAR antibody response in SIV-infected rhesus macaques treated with CD4-MBL CAR/CXCR5 T cells

Visualizing Antigen-Specific and Infected Cells in Situ Predicts Outcomes in Early Viral Infection

Assessment of anti-CD20 antibody pre-treatment for augmentation of CAR-T cell therapy in SIV-infected rhesus macaques

CTL Fail to Accumulate at Sites of HIV-1 Replication in Lymphoid Tissue

Antigenic cells augment CAR T cells

Rapid Transduction and Expansion of Transduced T Cells with Maintenance of Central Memory Populations

The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cell follicles

In Situ Peptide-MHC-II Tetramer Staining of Antigen-Specific CD4+ T Cells in Tissues

Treatment of Prion Disease with Heterologous Prion Proteins

Location and dynamics of the immunodominant CD8 T cell response to SIVΔnef immunization and SIVmac251 vaginal challenge

CD8+ T-Lymphocyte Response to Major Immunodominant Epitopes after Vaginal Exposure to Simian Immunodeficiency Virus: Too Late and Too Little

With Minimal Systemic T-Cell Expansion, CD8+ T Cells Mediate Protection of Rhesus Macaques Immunized with Attenuated Simian-Human Immunodeficiency Virus SHIV89.6 from Vaginal Challenge with Simian Immunodeficiency Virus

Gene expression alterations in brains of mice infected with three strains of scrapie

Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection

Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8+ Cells In Vivo

Follicular regulatory T cells impair follicular T helper cells in HIV and SIV infection

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