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Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials

The lancet respiratory medicine, 2018-07, Vol.6 (7), p.511-525

2018

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Plasminogen Is a Critical Host Pathogenicity Factor for Group A Streptococcal Infection

Science (American Association for the Advancement of Science), 2004-08, Vol.305 (5688), p.1283-1286

2004

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A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19

The Lancet regional health. Europe, 2021-05, Vol.4, p.100084, Article 100084

2021

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Budesonide and the risk of pneumonia: a meta-analysis of individual patient data

The Lancet (British edition), 2009-08, Vol.374 (9691), p.712-719

2009

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Injury Is a Major Inducer of Epidermal Innate Immune Responses during Wound Healing

Journal of investigative dermatology, 2010-04, Vol.130 (4), p.1167-1177

2010

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Injury-induced innate immune response in human skin mediated by transactivation of the epidermal growth factor receptor

The Journal of clinical investigation, 2006-07, Vol.116 (7), p.1878-1885

2006

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Induction of platelet thrombi by bacteria and antibodies

Blood, 2002-12, Vol.100 (13), p.4470-4477

2002

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Severe streptococcal infection is associated with M protein‐induced platelet activation and thrombus formation

Molecular microbiology, 2007-09, Vol.65 (5), p.1147-1157

2007

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EndoS and SpeB from Streptococcus pyogenes Inhibit Immunoglobulin-Mediated Opsonophagocytosis

Infection and Immunity, 2002-12, Vol.70 (12), p.6646-6651

2002

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Allelic variants of streptokinase from Streptococcus pyogenes display functional differences in plasminogen activation

The FASEB journal, 2008-09, Vol.22 (9), p.3146-3153

2008

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Staphylococcus aureus Induces Release of Bradykinin in Human Plasma

Infection and Immunity, 2001-06, Vol.69 (6), p.3877-3882

2001

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Activation of human polymorphonuclear neutrophils by streptolysin O from Streptococcus pyogenes leads to the release of proinflammatory mediators

Thrombosis and haemostasis, 2006-06, Vol.95 (6), p.982

2006

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Role of the Hypervariable Region in Streptococcal M Proteins: Binding of a Human Complement Inhibitor

The Journal of immunology (1950), 1998-11, Vol.161 (9), p.4894-4901

1998

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Identification of a Domain in Human Factor H and Factor H-Like Protein-1 Required for the Interaction with Streptococcal M Proteins

The Journal of immunology (1950), 1998-04, Vol.160 (7), p.3349-3354

1998

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Roles of the plasminogen activator streptokinase and the plasminogen-associated M protein in an experimental model for streptococcal impetigo

Microbiology (Society for General Microbiology), 2002-12, Vol.148 (Pt 12), p.3933

2002

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Streptococcal M5 Protein Prevents Neutrophil Phagocytosis by Interfering with CD11b/CD18 Receptor-Mediated Association and Signaling

The Journal of immunology (1950), 2004-03, Vol.172 (6), p.3798-3807

2004

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A role for the fibrinogen‐binding regions of streptococcal M proteins in phagocytosis resistance

Molecular microbiology, 2000-09, Vol.37 (6), p.1318-1326

2000

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Role for a secreted cysteine proteinase in the establishment of host tissue tropism by group A streptococci

Molecular microbiology, 2000-10, Vol.38 (2), p.242-253

2000

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Models of Exacerbations in Asthma and COPD

Schmidt, Herwald / Sjöbring, Taylor

1, 2007

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Selective Distribution of a High-Affinity Plasminogen-Binding Site among Group A Streptococci Associated with Impetigo

Infection and Immunity, 1999-08, Vol.67 (8), p.3915-3920

1999

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Strain-Specific Restriction of the Antiphagocytic Property of Group A Streptococcal M Proteins

Infection and Immunity, 2000-01, Vol.68 (1), p.107-112

2000

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Transient paradoxical bronchospasm associated with inhalation of the LAMA AZD9164: analysis of two Phase I, randomised, double-blind, placebo-controlled studies

BMC pulmonary medicine, 2014-03, Vol.14 (1), p.52-52, Article 52

2014

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Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells

European journal of biochemistry, 2003-05, Vol.270 (10), p.2303-2311

2003

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Human complement regulators: a major target for pathogenic microorganisms

Current opinion in immunology, 2000-02, Vol.12 (1), p.44-51

2000

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NMR analysis of the interaction between protein L and Ig light chains

Journal of molecular biology, 1997-07, Vol.270 (1), p.8-13

1997

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Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials

Plasminogen Is a Critical Host Pathogenicity Factor for Group A Streptococcal Infection

A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19

Budesonide and the risk of pneumonia: a meta-analysis of individual patient data

Injury Is a Major Inducer of Epidermal Innate Immune Responses during Wound Healing

Injury-induced innate immune response in human skin mediated by transactivation of the epidermal growth factor receptor

Induction of platelet thrombi by bacteria and antibodies

Severe streptococcal infection is associated with M protein‐induced platelet activation and thrombus formation

EndoS and SpeB from Streptococcus pyogenes Inhibit Immunoglobulin-Mediated Opsonophagocytosis

Allelic variants of streptokinase from Streptococcus pyogenes display functional differences in plasminogen activation

Staphylococcus aureus Induces Release of Bradykinin in Human Plasma

Activation of human polymorphonuclear neutrophils by streptolysin O from Streptococcus pyogenes leads to the release of proinflammatory mediators

Role of the Hypervariable Region in Streptococcal M Proteins: Binding of a Human Complement Inhibitor

Identification of a Domain in Human Factor H and Factor H-Like Protein-1 Required for the Interaction with Streptococcal M Proteins

Roles of the plasminogen activator streptokinase and the plasminogen-associated M protein in an experimental model for streptococcal impetigo

Streptococcal M5 Protein Prevents Neutrophil Phagocytosis by Interfering with CD11b/CD18 Receptor-Mediated Association and Signaling

A role for the fibrinogen‐binding regions of streptococcal M proteins in phagocytosis resistance

Role for a secreted cysteine proteinase in the establishment of host tissue tropism by group A streptococci

Models of Exacerbations in Asthma and COPD

Selective Distribution of a High-Affinity Plasminogen-Binding Site among Group A Streptococci Associated with Impetigo

Strain-Specific Restriction of the Antiphagocytic Property of Group A Streptococcal M Proteins

Transient paradoxical bronchospasm associated with inhalation of the LAMA AZD9164: analysis of two Phase I, randomised, double-blind, placebo-controlled studies

Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells

Human complement regulators: a major target for pathogenic microorganisms

NMR analysis of the interaction between protein L and Ig light chains

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