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Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities

Antioxidants & redox signaling, 2010-02, Vol.12 (4), p.537-577

2010

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Insulin and IGF-1 receptors regulate complex I-dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle

The Journal of clinical investigation, 2021-09, Vol.131 (18)

2021

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Human iPS cell-derived insulin producing cells form vascularized organoids under the kidney capsules of diabetic mice

PloS one, 2015-01, Vol.10 (1), p.e0116582-e0116582

2015

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Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (7), p.2366-2371

2007

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Voltage-Dependent Regulation of Complex II Energized Mitochondrial Oxygen Flux

PloS one, 2016-05, Vol.11 (5), p.e0154982-e0154982

2016

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Endothelial cell and platelet bioenergetics: effect of glucose and nutrient composition

PloS one, 2012-06, Vol.7 (6), p.e39430-e39430

2012

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Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells

The Journal of pharmacology and experimental therapeutics, 2012-09, Vol.342 (3), p.709-719

2012

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Reactive Oxygen and Targeted Antioxidant Administration in Endothelial Cell Mitochondria

The Journal of biological chemistry, 2006-12, Vol.281 (52), p.39766-39775

2006

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Dietary fat, fatty acid saturation and mitochondrial bioenergetics

Journal of bioenergetics and biomembranes, 2014-02, Vol.46 (1), p.33-44

2014

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Membrane potential‐dependent regulation of mitochondrial complex II by oxaloacetate in interscapular brown adipose tissue

FASEB bioAdvances, 2022-03, Vol.4 (3), p.197-210

2022

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Superoxide and Respiratory Coupling in Mitochondria of Insulin-Deficient Diabetic Rats

Endocrinology (Philadelphia), 2009-01, Vol.150 (1), p.46-55

2009

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A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation

Journal of medicinal chemistry, 2021-01, Vol.64 (1), p.662-676

2021

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Regulation of ATP production: dependence on calcium concentration and respiratory state

American Journal of Physiology: Cell Physiology, 2017-08, Vol.313 (2), p.C146-C153

2017

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Effect of the mitochondrial transaminase (GOT2) on membrane potential-sensitive respiration in mitochondria of differentiated C2C12 muscle cells

American Journal of Physiology: Cell Physiology, 2024-06, Vol.326 (6), p.C1669

2024

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Oxaloacetate regulates complex II respiration in brown fat: dependence on UCP1 expression

American Journal of Physiology: Cell Physiology, 2023-06, Vol.324 (6), p.C1236-C1248

2023

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Effect of mitoquinone on liver metabolism and steatosis in obese and diabetic rats

Pharmacology research & perspectives, 2021-02, Vol.9 (1), p.e00701-n/a

2021

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Interactions Between the Melanocortin System and Leptin in Control of Sympathetic Nerve Traffic

Hypertension (Dallas, Tex. 1979), 1999-01, Vol.33 (1S Suppl), p.542-547

1999

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Modulation of complex II‐energized respiration in muscle, heart, and brown adipose mitochondria by oxaloacetate and complex I electron flow

The FASEB journal, 2019-11, Vol.33 (11), p.11696-11705

2019

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Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study

Diabetes care, 2019-04, Vol.42 (4), p.657-664

2019

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Metabolic clearance of oxaloacetate and mitochondrial complex II respiration: Divergent control in skeletal muscle and brown adipose tissue

Biochimica et biophysica acta. Bioenergetics, 2023-01, Vol.1864 (1), p.148930-148930, Article 148930

2023

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CaMKII determines mitochondrial stress responses in heart

Nature (London), 2012-11, Vol.491 (7423), p.269-273

2012

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Simultaneous Quantification of Mitochondrial ATP and ROS Production Using ATP Energy Clamp Methodology

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2276, p.271

2021

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Sympathetic and Cardiorenal Actions of Leptin

Hypertension (Dallas, Tex. 1979), 1997-09, Vol.30 (3), p.619-623

1997

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Mitochondrial superoxide and coenzyme Q in insulin-deficient rats: increased electron leak

American journal of physiology. Regulatory, integrative and comparative physiology, 2011-12, Vol.301 (6), p.R1616-R1624

2011

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Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II–driven respiration

The Journal of biological chemistry, 2018-12, Vol.293 (51), p.19932-19941

2018

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Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities

Insulin and IGF-1 receptors regulate complex I-dependent mitochondrial bioenergetics and supercomplexes via FoxOs in muscle

Human iPS cell-derived insulin producing cells form vascularized organoids under the kidney capsules of diabetic mice

Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice

Voltage-Dependent Regulation of Complex II Energized Mitochondrial Oxygen Flux

Endothelial cell and platelet bioenergetics: effect of glucose and nutrient composition

Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells

Reactive Oxygen and Targeted Antioxidant Administration in Endothelial Cell Mitochondria

Dietary fat, fatty acid saturation and mitochondrial bioenergetics

Membrane potential‐dependent regulation of mitochondrial complex II by oxaloacetate in interscapular brown adipose tissue

Superoxide and Respiratory Coupling in Mitochondria of Insulin-Deficient Diabetic Rats

A Novel Triphenylphosphonium Carrier to Target Mitochondria without Uncoupling Oxidative Phosphorylation

Regulation of ATP production: dependence on calcium concentration and respiratory state

Effect of the mitochondrial transaminase (GOT2) on membrane potential-sensitive respiration in mitochondria of differentiated C2C12 muscle cells

Oxaloacetate regulates complex II respiration in brown fat: dependence on UCP1 expression

Effect of mitoquinone on liver metabolism and steatosis in obese and diabetic rats

Interactions Between the Melanocortin System and Leptin in Control of Sympathetic Nerve Traffic

Modulation of complex II‐energized respiration in muscle, heart, and brown adipose mitochondria by oxaloacetate and complex I electron flow

Association of Insulin Dose, Cardiometabolic Risk Factors, and Cardiovascular Disease in Type 1 Diabetes During 30 Years of Follow-up in the DCCT/EDIC Study

Metabolic clearance of oxaloacetate and mitochondrial complex II respiration: Divergent control in skeletal muscle and brown adipose tissue

CaMKII determines mitochondrial stress responses in heart

Simultaneous Quantification of Mitochondrial ATP and ROS Production Using ATP Energy Clamp Methodology

Sympathetic and Cardiorenal Actions of Leptin

Mitochondrial superoxide and coenzyme Q in insulin-deficient rats: increased electron leak

Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II–driven respiration

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