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Fibroblast-Activating Protein: Targeting the Roots of the Tumor Microenvironment

Journal of Nuclear Medicine, 2018-09, Vol.59 (9), p.1412-1414

Siveke, Jens T

2018

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NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors

European journal of cancer (1990), 2019-02, Vol.108, p.78-87

2019

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Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis

PloS one, 2017-12, Vol.12 (12), p.e0190074

2017

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A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy

PloS one, 2019-10, Vol.14 (10), p.e0218642

2019

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Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity

Angewandte Chemie International Edition, 2019-12, Vol.58 (52), p.18823-18829

International ed. in English, 2019

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Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma

International journal of molecular sciences, 2021-07, Vol.22 (13), p.6727

2021

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Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice

Hepatology (Baltimore, Md.), 2015-01, Vol.61 (1), p.238-248

2015

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Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma

Oncogene, 2020-06, Vol.39 (24), p.4770-4779

2020

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Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner

Nucleic acids research, 2017-06, Vol.45 (11), p.6334-6349

2017

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The role of insulin and IGF system in pancreatic cancer

Journal of molecular endocrinology, 2013-06, Vol.50 (3), p.R67-R74

2013

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Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression

Nature communications, 2021-06, Vol.12 (1), p.3895-3895, Article 3895

2021

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Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma – The SHELTER study

Journal of hepatology, 2016-08, Vol.65 (2), p.280-288

2016

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Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways

Modern pathology, 2014-01, Vol.27 (1), p.73-86

2014

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Resectability After First-Line FOLFIRINOX in Initially Unresectable Locally Advanced Pancreatic Cancer: A Single-Center Experience

Annals of surgical oncology, 2015-12, Vol.22 (Suppl 3), p.1212-1220

2015

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Cellular model system to dissect the isoform-selectivity of Akt inhibitors

Nature communications, 2021-09, Vol.12 (1), p.5297-14, Article 5297

2021

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Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

Proceedings of the National Academy of Sciences - PNAS, 2010-07, Vol.107 (30), p.13438-13443

2010

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Pancreatic Cancer: Basic and Clinical Aspects

Gastroenterology (New York, N.Y. 1943), 2005-05, Vol.128 (6), p.1606-1625

2005

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Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1

Hepatology (Baltimore, Md.), 2013-06, Vol.57 (6), p.2469-2479

2013

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Early Requirement of Rac1 in a Mouse Model of Pancreatic Cancer

Gastroenterology (New York, N.Y. 1943), 2011-08, Vol.141 (2), p.719-730.e7

2011

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Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatment

Nature communications, 2024-05, Vol.15 (1), p.4120-4120, Article 4120

2024

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[ 68 Ga]FAPI-PET/CT for radiation therapy planning in biliary tract, pancreatic ductal adeno-, and adenoidcystic carcinomas

Scientific reports, 2022-09, Vol.12 (1), p.16261-14, Article 16261

2022

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SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis

Molecular cancer, 2023-03, Vol.22 (1), p.52-52, Article 52

2023

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Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer

Translational oncology, 2022-01, Vol.15 (1), p.101279-101279, Article 101279

2022

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Validation of Heat Shock Protein 70 as a Tumor-Specific Biomarker for Monitoring the Outcome of Radiation Therapy in Tumor Mouse Models

International journal of radiation oncology, biology, physics, 2014-03, Vol.88 (3), p.694-700

2014

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Fibroblast-Activating Protein: Targeting the Roots of the Tumor Microenvironment

NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors

Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer

Knockdown of myeloid cell hypoxia-inducible factor-1α ameliorates the acute pathology in DSS-induced colitis

A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy

Covalent‐Allosteric Inhibitors to Achieve Akt Isoform‐Selectivity

Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma

Tissue inhibitor of metalloproteinases (TIMP)‐1 creates a premetastatic niche in the liver through SDF‐1/CXCR4‐dependent neutrophil recruitment in mice

Therapeutic targeting of p300/CBP HAT domain for the treatment of NUT midline carcinoma

Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner

The role of insulin and IGF system in pancreatic cancer

Tumor-associated hematopoietic stem and progenitor cells positively linked to glioblastoma progression

Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma – The SHELTER study

Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways

Resectability After First-Line FOLFIRINOX in Initially Unresectable Locally Advanced Pancreatic Cancer: A Single-Center Experience

Cellular model system to dissect the isoform-selectivity of Akt inhibitors

Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

Pancreatic Cancer: Basic and Clinical Aspects

Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1

Early Requirement of Rac1 in a Mouse Model of Pancreatic Cancer

Cell-mediated cytotoxicity within CSF and brain parenchyma in spinal muscular atrophy unaltered by nusinersen treatment

[ 68 Ga]FAPI-PET/CT for radiation therapy planning in biliary tract, pancreatic ductal adeno-, and adenoidcystic carcinomas

SOX2 dosage sustains tumor-promoting inflammation to drive disease aggressiveness by modulating the FOSL2/IL6 axis

Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer

Validation of Heat Shock Protein 70 as a Tumor-Specific Biomarker for Monitoring the Outcome of Radiation Therapy in Tumor Mouse Models

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