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Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage

PLoS biology, 2023-03, Vol.21 (3), p.e3002023-e3002023

2023

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Crystal structure of HECT domain of UBE3C E3 ligase and its ubiquitination activity

Biochemical journal, 2020-03, Vol.477 (5), p.905-923

2020

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Structural Basis of SARS-CoV-2 and SARS-CoV Antibody Interactions

Trends in immunology, 2020-11, Vol.41 (11), p.1006-1022

2020

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Exploring the “Other” subfamily of HECT E3-ligases for therapeutic intervention

Pharmacology & therapeutics (Oxford), 2021-08, Vol.224, p.107809, Article 107809

2021

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Linkers in the structural biology of protein–protein interactions

Protein science, 2013-02, Vol.22 (2), p.153-167

2013

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Identification of Aedes aegypti salivary gland proteins interacting with human immune receptor proteins

PLoS neglected tropical diseases, 2022-09, Vol.16 (9), p.e0010743-e0010743

2022

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Structural Basis of SARS-CoV-2- and SARS-CoV-Receptor Binding and Small-Molecule Blockers as Potential Therapeutics

Annual review of pharmacology and toxicology, 2021-01, Vol.61 (1), p.465-493

2021

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Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1

Journal of molecular biology, 2018-04, Vol.430 (8), p.1173-1188

2018

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Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (20), p.7705-7710

2012

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Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities in vitro

The Journal of biological chemistry, 2019-12, Vol.294 (52), p.19934-19949

2019

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Structural basis for the distinct roles of non-conserved Pro116 and conserved Tyr124 of BCH domain of yeast p50RhoGAP

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.216, Article 216

2024

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Sensing for survival: specialised regulatory mechanisms of Type III secretion systems in Gram‐negative pathogens

Biological reviews of the Cambridge Philosophical Society, 2024-06, Vol.99 (3), p.837-863

2024

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A novel allosteric site employs a conserved inhibition mechanism in human kidney‐type glutaminase

The FEBS journal, 2023-05, Vol.290 (9), p.2437-2448

2023

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Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA)

Scientific reports, 2014-01, Vol.4 (1), p.3827, Article 3827

2014

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Berberine Targets Assembly of Escherichia coli Cell Division Protein FtsZ

Biochemistry (Easton), 2008-03, Vol.47 (10), p.3225-3234

2008

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Two-component PhoB-PhoR Regulatory System and Ferric Uptake Regulator Sense Phosphate and Iron to Control Virulence Genes in Type III and VI Secretion Systems of Edwardsiella tarda

The Journal of biological chemistry, 2011-11, Vol.286 (45), p.39417-39430

2011

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Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease

Journal of Virology, 2008-05, Vol.82 (9), p.4620-4629

2008

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Inhibition of bacterial cell division protein FtsZ by cinnamaldehyde

Biochemical pharmacology, 2007-09, Vol.74 (6), p.831-840

2007

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Unusual quaternary structure of a homodimeric synergistic-type toxin from mamba snake venom defines its molecular evolution

Biochemical journal, 2020-10, Vol.477 (20), p.3951-3962

2020

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Mapping of molecular interactions between human E3 ligase TRIM69 and Dengue virus NS3 protease using hydrogen–deuterium exchange mass spectrometry

Cellular and molecular life sciences : CMLS, 2022-05, Vol.79 (5), p.233-233, Article 233

2022

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Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction

PLoS pathogens, 2009-08, Vol.5 (8), p.e1000537-e1000537

2009

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Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site

Biochemistry (Easton), 2020-08, Vol.59 (30), p.2788-2795

2020

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Structural basis for the pathogenesis of Campylobacter jejuni Hcp1, a structural and effector protein of the Type VI Secretion System

The FEBS journal, 2018-11, Vol.285 (21), p.4060-4070

2018

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Structural and functional characterization of Aedes aegypti pupal cuticle protein that controls dengue virus infection

Protein science, 2023-10, Vol.32 (10), p.e4761-e4761

2023

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Sequence preference and scaffolding requirement for the inhibition of human neutrophil elastase by ecotin peptide

Protein science, 2022-04, Vol.31 (4), p.933-941

2022

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Structures of apo Cas12a and its complex with crRNA and DNA reveal the dynamics of ternary complex formation and target DNA cleavage

Crystal structure of HECT domain of UBE3C E3 ligase and its ubiquitination activity

Structural Basis of SARS-CoV-2 and SARS-CoV Antibody Interactions

Exploring the “Other” subfamily of HECT E3-ligases for therapeutic intervention

Linkers in the structural biology of protein–protein interactions

Identification of Aedes aegypti salivary gland proteins interacting with human immune receptor proteins

Structural Basis of SARS-CoV-2- and SARS-CoV-Receptor Binding and Small-Molecule Blockers as Potential Therapeutics

Structure of LNX1:Ubc13~Ubiquitin Complex Reveals the Role of Additional Motifs for the E3 Ligase Activity of LNX1

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activities in vitro

Structural basis for the distinct roles of non-conserved Pro116 and conserved Tyr124 of BCH domain of yeast p50RhoGAP

Sensing for survival: specialised regulatory mechanisms of Type III secretion systems in Gram‐negative pathogens

A novel allosteric site employs a conserved inhibition mechanism in human kidney‐type glutaminase

Structural basis for the active site inhibition mechanism of human kidney-type glutaminase (KGA)

Berberine Targets Assembly of Escherichia coli Cell Division Protein FtsZ

Two-component PhoB-PhoR Regulatory System and Ferric Uptake Regulator Sense Phosphate and Iron to Control Virulence Genes in Type III and VI Secretion Systems of Edwardsiella tarda

Mechanism for Controlling the Dimer-Monomer Switch and Coupling Dimerization to Catalysis of the Severe Acute Respiratory Syndrome Coronavirus 3C-Like Protease

Inhibition of bacterial cell division protein FtsZ by cinnamaldehyde

Unusual quaternary structure of a homodimeric synergistic-type toxin from mamba snake venom defines its molecular evolution

Mapping of molecular interactions between human E3 ligase TRIM69 and Dengue virus NS3 protease using hydrogen–deuterium exchange mass spectrometry

Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction

Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site

Structural basis for the pathogenesis of Campylobacter jejuni Hcp1, a structural and effector protein of the Type VI Secretion System

Structural and functional characterization of Aedes aegypti pupal cuticle protein that controls dengue virus infection

Sequence preference and scaffolding requirement for the inhibition of human neutrophil elastase by ecotin peptide

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