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Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation

The Journal of experimental medicine, 2017-04, Vol.214 (4), p.1093-1109

2017

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Effects of heterozygous deletion of autism-related gene Cullin-3 in mice

PloS one, 2023-07, Vol.18 (7), p.e0283299-e0283299

2023

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Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3

The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4723-4736

2014

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Autism risk gene Cul3 alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons

Frontiers in cellular neuroscience, 2024-05, Vol.18, p.1320784-1320784

2024

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Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

American journal of physiology. Renal physiology, 2018-10, Vol.315 (4), p.F1006-F1018

2018

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BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs

Nature (London), 2012-11, Vol.491 (7425), p.618-621

2012

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The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer

Molecular biology of the cell, 2007-03, Vol.18 (3), p.899-909

2007

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Subcellular localization and cytoplasmic complex status of endogenous Keap1

Genes to cells : devoted to molecular & cellular mechanisms, 2007-10, Vol.12 (10), p.1163-1178

2007

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Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension

Biochemical and biophysical research communications, 2016-01, Vol.469 (1), p.44-48

2016

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The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells

The Journal of clinical investigation, 2010-11, Vol.120 (11), p.3820-3833

2010

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Constitutive Turnover of Cyclin E by Cul3 Maintains Quiescence

Molecular and Cellular Biology, 2007-05, Vol.27 (10), p.3651-3666

2007

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Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension

JCI insight, 2019-07, Vol.5 (14)

2019

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B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1)

Cell cycle (Georgetown, Tex.), 2012-11, Vol.11 (21), p.4047-4058

2012

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Cul3 is required for normal development of the mammary gland

Cell and tissue research, 2021-07, Vol.385 (1), p.49-63

2021

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The Cul3/Klhdc5 E3 Ligase Regulates p60/Katanin and Is Required for Normal Mitosis in Mammalian Cells

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11663-11675

2009

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Actinfilin Is a Cul3 Substrate Adaptor, Linking GluR6 Kainate Receptor Subunits to the Ubiquitin-Proteasome Pathway

The Journal of biological chemistry, 2006-12, Vol.281 (52), p.40164-40173

2006

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Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E

Journal of cell science, 2019-11, Vol.132 (21)

2019

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Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy

Human molecular genetics, 2016-06, Vol.25 (11), p.2143-2157

2016

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Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis

Scientific reports, 2019-03, Vol.9 (1), p.4596, Article 4596

2019

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Cullin 3-Mediated Regulation of Intracellular Iron Homeostasis Promotes Thymic Invariant NKT Cell Maturation

ImmunoHorizons, 2023-03, Vol.7 (3), p.235-242

2023

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Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice

The Journal of clinical investigation, 2010-10, Vol.120 (10), p.3713-3721

2010

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Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects

JCI insight, 2017-12, Vol.2 (24)

2017

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A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation

The Journal of experimental medicine, 2014-06, Vol.211 (6), p.1137-1151

2014

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Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells

Chemical communications (Cambridge, England), 2014-01, Vol.50 (10), p.1234-1237

2014

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The Ubiquitin Conjugating Enzyme, UbcM2, Engages in Novel Interactions with Components of Cullin-3 Based E3 Ligases

Biochemistry (Easton), 2009-04, Vol.48 (15), p.3527-3537

2009

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Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation

Effects of heterozygous deletion of autism-related gene Cullin-3 in mice

Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3

Autism risk gene Cul3 alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons

Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension

BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs

The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer

Subcellular localization and cytoplasmic complex status of endogenous Keap1

Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension

The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells

Constitutive Turnover of Cyclin E by Cul3 Maintains Quiescence

Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension

B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1)

Cul3 is required for normal development of the mammary gland

The Cul3/Klhdc5 E3 Ligase Regulates p60/Katanin and Is Required for Normal Mitosis in Mammalian Cells

Actinfilin Is a Cul3 Substrate Adaptor, Linking GluR6 Kainate Receptor Subunits to the Ubiquitin-Proteasome Pathway

Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E

Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in giant axonal neuropathy

Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis

Cullin 3-Mediated Regulation of Intracellular Iron Homeostasis Promotes Thymic Invariant NKT Cell Maturation

Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice

Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects

A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation

Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells

The Ubiquitin Conjugating Enzyme, UbcM2, Engages in Novel Interactions with Components of Cullin-3 Based E3 Ligases

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