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Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (19), p.5316-5319

2008

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Preliminary SAR studies on non-apamin-displacing 4-(aminomethylaryl)pyrrazolopyrimidine KCa channel blockers

Bioorganic & medicinal chemistry letters, 2008-10, Vol.18 (20), p.5694-5697

2008

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Identification of a Potent and Selective 5-HT6 Antagonist: One-Step Synthesis of (E)-3-(Benzenesulfonyl)-2- (methylsulfanyl)pyrido[1,2-a]pyrimidin- 4-ylidenamine from 2-(Benzenesulfonyl)-3,3- bis(methylsulfanyl)acrylonitrile

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4834-4837

2003

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Discovery of D1 Dopamine Receptor Positive Allosteric Modulators: Characterization of Pharmacology and Identification of Residues that Regulate Species Selectivity

The Journal of pharmacology and experimental therapeutics, 2015-09, Vol.354 (3), p.340-349

2015

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Structure activity relationship studies on chemically non-reactive glycine sulfonamide inhibitors of diacylglycerol lipase

Bioorganic & medicinal chemistry, 2016-04, Vol.24 (7), p.1455-1468

2016

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Total Synthesis of a Human Breast Tumor Associated Antigen

Journal of the American Chemical Society, 1995-07, Vol.117 (29), p.7840-7841

1995

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Structure activity relationship studies of 3-arylsulfonyl-pyrido[1,2-a]pyrimidin-4-imines as potent 5-HT6 antagonists

Bioorganic & medicinal chemistry, 2014-03, Vol.22 (5), p.1782-1790

2014

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Heterocyclic modification of a novel bicyclo[3.1.0]hexane NPY1 receptor antagonist

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (13), p.3814-3817

2013

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Preliminary SAR studies on non-apamin-displacing 4-(aminomethylaryl)pyrrazolopyrimidine K Ca channel blockers

Bioorganic & medicinal chemistry letters, 2008-10, Vol.18 (20), p.5694-5697

2008

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Preliminary SAR studies on non-apamin-displacing 4- (aminomethylaryl)pyrrazolopyrimidine K sub(Ca) channel blockers

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (20), p.5694-5697

2008

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Discovery of a Novel Class of Bicyclo[3.1.0]hexanylpiperazines as Noncompetitive Neuropeptide Y Y1 Antagonists

ACS medicinal chemistry letters, 2012-03, Vol.3 (3), p.222-226

2012

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A Highly Convergent Total Synthetic Route to Glycopeptides Carrying a High-Mannose Core Pentasaccharide Domain N-linked to a Natural Peptide Motif

Chemistry : a European journal, 1997-10, Vol.3 (10), p.1617-1628

1997

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A novel route to the 5,6-dihydro-4-H-thieno[3,2-b]pyrrol-5-one ring system involving an intermediate substituted-thiophene synthesis

Journal of heterocyclic chemistry, 2005-05, Vol.42 (4), p.661-667

2005

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Unbleachable rhodopsin with an 11-cis-locked eight-membered ring retinal: The visual transduction process

Biochemistry (Easton), 1994-01, Vol.33 (2), p.408-416

1994

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Identification of a potent and selective 5-HT(6) antagonist: one-step synthesis of (E)-3-(benzenesulfonyl)-2- (methylsulfanyl)pyrido[1,2-a]pyrimidin-4-ylidenamine from 2-(benzenesulfonyl)-3,3-bis(methylsulfanyl)acrylonitrile

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4834

2003

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Identification of a Potent and Selective 5-HT 6 Antagonist: One-Step Synthesis of ( E )-3-(Benzenesulfonyl)-2- (methylsulfanyl)pyrido[1,2- a ]pyrimidin- 4-ylidenamine from 2-(Benzenesulfonyl)-3,3- bis(methylsulfanyl)acrylonitrile

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4834-4837

2003

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Preliminary SAR studies on non-apamin-displacing 4-(aminomethylaryl)pyrrazolopyrimidine K(Ca) channel blockers

Bioorganic & medicinal chemistry letters, 2008-10, Vol.18 (20), p.5694

2008

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Synthesis of retinals with eight- and nine-membered rings in the side chain. Models for rhodopsin photobleaching intermediates

Journal of organic chemistry, 1993-06, Vol.58 (13), p.3533-3537

1993

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Sorafenib (Nexavar): A Multikinase Inhibitor for Advanced Renal Cell Carcinoma and Unresectable Hepatocellular Carcinoma

Modern Drug Synthesis, 2010, p.73-85

2010

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Bioorganic studies on the activation of rhodopsin in the visual transduction process

Hu, Shuanghua

1995

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Bioactivity of Visual Pigments with Sterically Modified Retinal Analogs

Bioorganic chemistry, 1999-10, Vol.27 (5), p.372-382

1999

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Defining the Molecular Recognition of MBr1 (Human Breast Cancer) Antigen by the MBr1 Antibody through Probe Structures Prepared by Total Synthesis

Journal of organic chemistry, 1995-12, Vol.60 (24), p.7716-7717

1995

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Total Synthesis and Proof of Structure of a Human Breast Tumor (Globo-H) Antigen

Journal of the American Chemical Society, 1996-11, Vol.118 (46), p.11488-11500

1996

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Unbleachable rhodopsin with an 11-cis-locked eight-membered ring retinal: The visual transduction process. [Erratum to document cited in CA120(7):74157z]

Biochemistry (Easton), 1994-04, Vol.33 (16), p.4994-4994

1994

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A Novel Route to the 5,6-Dihydro-4H-thieno[3,2-b]pyrrol-5-one Ring System Involving an Intermediate Substituted-Thiophene Synthesis

ChemInform, 2005-10, Vol.36 (41), p.no-no

2005

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Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels

Preliminary SAR studies on non-apamin-displacing 4-(aminomethylaryl)pyrrazolopyrimidine KCa channel blockers

Identification of a Potent and Selective 5-HT6 Antagonist: One-Step Synthesis of (E)-3-(Benzenesulfonyl)-2- (methylsulfanyl)pyrido[1,2-a]pyrimidin- 4-ylidenamine from 2-(Benzenesulfonyl)-3,3- bis(methylsulfanyl)acrylonitrile

Discovery of D1 Dopamine Receptor Positive Allosteric Modulators: Characterization of Pharmacology and Identification of Residues that Regulate Species Selectivity

Structure activity relationship studies on chemically non-reactive glycine sulfonamide inhibitors of diacylglycerol lipase

Total Synthesis of a Human Breast Tumor Associated Antigen

Structure activity relationship studies of 3-arylsulfonyl-pyrido[1,2-a]pyrimidin-4-imines as potent 5-HT6 antagonists

Heterocyclic modification of a novel bicyclo[3.1.0]hexane NPY1 receptor antagonist

Preliminary SAR studies on non-apamin-displacing 4-(aminomethylaryl)pyrrazolopyrimidine K Ca channel blockers

Preliminary SAR studies on non-apamin-displacing 4- (aminomethylaryl)pyrrazolopyrimidine K sub(Ca) channel blockers

Discovery of a Novel Class of Bicyclo[3.1.0]hexanylpiperazines as Noncompetitive Neuropeptide Y Y1 Antagonists

A Highly Convergent Total Synthetic Route to Glycopeptides Carrying a High-Mannose Core Pentasaccharide Domain N-linked to a Natural Peptide Motif

A novel route to the 5,6-dihydro-4-H-thieno[3,2-b]pyrrol-5-one ring system involving an intermediate substituted-thiophene synthesis

Unbleachable rhodopsin with an 11-cis-locked eight-membered ring retinal: The visual transduction process

Identification of a potent and selective 5-HT(6) antagonist: one-step synthesis of (E)-3-(benzenesulfonyl)-2- (methylsulfanyl)pyrido[1,2-a]pyrimidin-4-ylidenamine from 2-(benzenesulfonyl)-3,3-bis(methylsulfanyl)acrylonitrile

Identification of a Potent and Selective 5-HT 6 Antagonist: One-Step Synthesis of ( E )-3-(Benzenesulfonyl)-2- (methylsulfanyl)pyrido[1,2- a ]pyrimidin- 4-ylidenamine from 2-(Benzenesulfonyl)-3,3- bis(methylsulfanyl)acrylonitrile

Preliminary SAR studies on non-apamin-displacing 4-(aminomethylaryl)pyrrazolopyrimidine K(Ca) channel blockers

Synthesis of retinals with eight- and nine-membered rings in the side chain. Models for rhodopsin photobleaching intermediates

Sorafenib (Nexavar): A Multikinase Inhibitor for Advanced Renal Cell Carcinoma and Unresectable Hepatocellular Carcinoma

Bioorganic studies on the activation of rhodopsin in the visual transduction process

Bioactivity of Visual Pigments with Sterically Modified Retinal Analogs

Defining the Molecular Recognition of MBr1 (Human Breast Cancer) Antigen by the MBr1 Antibody through Probe Structures Prepared by Total Synthesis

Total Synthesis and Proof of Structure of a Human Breast Tumor (Globo-H) Antigen

Unbleachable rhodopsin with an 11-cis-locked eight-membered ring retinal: The visual transduction process. [Erratum to document cited in CA120(7):74157z]

A Novel Route to the 5,6-Dihydro-4H-thieno[3,2-b]pyrrol-5-one Ring System Involving an Intermediate Substituted-Thiophene Synthesis

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