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Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy

Neuropharmacology, 2021-04, Vol.187, p.108498-108498, Article 108498

2021

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Targeting cancer metabolic vulnerabilities for advanced therapeutic efficacy

Biomedicine & pharmacotherapy, 2023-06, Vol.162, p.114658-114658, Article 114658

2023

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Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1

Oncogene, 2020-01, Vol.39 (5), p.1004-1017

2020

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The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid‐inducible gene‐I‐like receptor signalling and is a potential prognostic biomarker for colon cancer

The Journal of pathology, 2018-01, Vol.244 (1), p.36-48

2018

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Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer

Theranostics, 2020-01, Vol.10 (22), p.10016-10030

2020

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A distal super-enhancer activates oncogenic ETS2 via recruiting MECOM in inflammatory bowel disease and colorectal cancer

Cell death & disease, 2023-01, Vol.14 (1), p.8-8, Article 8

2023

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CDCA2 Inhibits Apoptosis and Promotes Cell Proliferation in Prostate Cancer and Is Directly Regulated by HIF-1α Pathway

Frontiers in oncology, 2020-05, Vol.10, p.725-725

2020

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A Novel Strategy Conjugating PD-L1 Polypeptide With Doxorubicin Alleviates Chemotherapeutic Resistance and Enhances Immune Response in Colon Cancer

Frontiers in oncology, 2021-11, Vol.11, p.737323-737323

2021

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The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors

PloS one, 2011-11, Vol.6 (11), p.e27346-e27346

2011

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Extract from Moringa oleifera seeds suppresses the epithelial-mesenchymal transition-mediated metastasis of gastric cancer by targeting the metastatic suppressor NDRG1

Journal of functional foods, 2018-11, Vol.50, p.93-103

2018

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Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method

Communications biology, 2020-07, Vol.3 (1), p.403-403, Article 403

2020

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Targeting the Epigenetic Reader ENL Inhibits Super-Enhancer-Driven Oncogenic Transcription and Synergizes with BET Inhibition to Suppress Tumor Progression

Cancer research (Chicago, Ill.), 2024-04, Vol.84 (8), p.1237-1251

2024

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Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas

iScience, 2019-11, Vol.21, p.1-18

2019

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Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci

Proceedings of the National Academy of Sciences - PNAS, 2022-05, Vol.119 (22), p.e2120633119-e2120633119

2022

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Overexpression of a novel candidate oncogene KIF14 correlates with tumor progression and poor prognosis in prostate cancer

Oncotarget, 2017-07, Vol.8 (28), p.45459-45469

2017

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Neuroprotective Effects of Ginsenoside Rg1 against Hyperphosphorylated Tau-Induced Diabetic Retinal Neurodegeneration via Activation of IRS-1/Akt/GSK3β Signaling

Journal of agricultural and food chemistry, 2019-07, Vol.67 (30), p.8348-8360

2019

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Loss of β-catenin via activated GSK3β causes diabetic retinal neurodegeneration by instigating a vicious cycle of oxidative stress-driven mitochondrial impairment

Aging (Albany, NY.), 2020-06, Vol.12 (13), p.13437-13462

2020

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A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy

Cell death and differentiation, 2023-05, Vol.30 (5), p.1166-1183

2023

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Emerging role of PR domain containing 5 (PRDM5) as a broad tumor suppressor in human cancers

Tumor biology, 2015-01, Vol.36 (1), p.1-3

Shu, Xing-sheng

2015

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OSR1 is a novel epigenetic silenced tumor suppressor regulating invasion and proliferation in renal cell carcinoma

Oncotarget, 2017-05, Vol.8 (18), p.30008-30018

2017

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FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma

Carcinogenesis (New York), 2013-09, Vol.34 (9), p.1984-1993

2013

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Chromatin regulators with tumor suppressor properties and their alterations in human cancers

Epigenomics, 2012-10, Vol.4 (5), p.537-549

2012

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CMTM3, Located at the Critical Tumor Suppressor Locus 16q22.1, Is Silenced by CpG Methylation in Carcinomas and Inhibits Tumor Cell Growth through Inducing Apoptosis

Cancer research (Chicago, Ill.), 2009-06, Vol.69 (12), p.5194-5201

2009

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Epigenetic disruption of cell signaling in nasopharyngeal carcinoma

Ai zheng, 2011-04, Vol.30 (4), p.231-239

2011

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Effect of Frequency on Emission of XeI Excimer in a Pulsed Dielectric Barrier Discharge

Chinese physics letters, 2004-07, Vol.21 (7), p.1317-1319

2004

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Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy

Targeting cancer metabolic vulnerabilities for advanced therapeutic efficacy

Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1

The epigenetic modifier PBRM1 restricts the basal activity of the innate immune system by repressing retinoic acid‐inducible gene‐I‐like receptor signalling and is a potential prognostic biomarker for colon cancer

Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer

A distal super-enhancer activates oncogenic ETS2 via recruiting MECOM in inflammatory bowel disease and colorectal cancer

CDCA2 Inhibits Apoptosis and Promotes Cell Proliferation in Prostate Cancer and Is Directly Regulated by HIF-1α Pathway

A Novel Strategy Conjugating PD-L1 Polypeptide With Doxorubicin Alleviates Chemotherapeutic Resistance and Enhances Immune Response in Colon Cancer

The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors

Extract from Moringa oleifera seeds suppresses the epithelial-mesenchymal transition-mediated metastasis of gastric cancer by targeting the metastatic suppressor NDRG1

Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method

Targeting the Epigenetic Reader ENL Inhibits Super-Enhancer-Driven Oncogenic Transcription and Synergizes with BET Inhibition to Suppress Tumor Progression

Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas

Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci

Overexpression of a novel candidate oncogene KIF14 correlates with tumor progression and poor prognosis in prostate cancer

Neuroprotective Effects of Ginsenoside Rg1 against Hyperphosphorylated Tau-Induced Diabetic Retinal Neurodegeneration via Activation of IRS-1/Akt/GSK3β Signaling

Loss of β-catenin via activated GSK3β causes diabetic retinal neurodegeneration by instigating a vicious cycle of oxidative stress-driven mitochondrial impairment

A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy

Emerging role of PR domain containing 5 (PRDM5) as a broad tumor suppressor in human cancers

OSR1 is a novel epigenetic silenced tumor suppressor regulating invasion and proliferation in renal cell carcinoma

FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma

Chromatin regulators with tumor suppressor properties and their alterations in human cancers

CMTM3, Located at the Critical Tumor Suppressor Locus 16q22.1, Is Silenced by CpG Methylation in Carcinomas and Inhibits Tumor Cell Growth through Inducing Apoptosis

Epigenetic disruption of cell signaling in nasopharyngeal carcinoma

Effect of Frequency on Emission of XeI Excimer in a Pulsed Dielectric Barrier Discharge

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