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Cisplatin Induces Endoplasmic Reticulum Stress and Nucleus-independent Apoptotic Signaling

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9100-9106

2003

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Induction of Lysosomal Membrane Permeabilization by Compounds That Activate p53-Independent Apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2005-01, Vol.102 (1), p.192-197

2005

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Potentiation of anti-cancer treatment by modulators of energy metabolism

Current pharmaceutical biotechnology, 2013, Vol.14 (3), p.313

Shoshan, Maria C

2013

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3-bromopyruvate: Targets and outcomes

Journal of bioenergetics and biomembranes, 2012-02, Vol.44 (1), p.7-15

Shoshan, Maria C.

2012

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Cytokeratin-18 Is a Useful Serum Biomarker for Early Determination of Response of Breast Carcinomas to Chemotherapy

Clinical cancer research, 2007-06, Vol.13 (11), p.3198-3206

2007

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Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18

Cancer research (Chicago, Ill.), 2004-03, Vol.64 (5), p.1751-1756

2004

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Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2‐deoxyglucose and etomoxir

International journal of cancer, 2008-07, Vol.123 (2), p.476-483

2008

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Calpain-Mediated Bid Cleavage and Calpain-Independent Bak Modulation: Two Separate Pathways in Cisplatin-Induced Apoptosis

Molecular and Cellular Biology, 2002-05, Vol.22 (9), p.3003-3013

2002

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Activation of Bak, Bax, and BH3-only Proteins in the Apoptotic Response to Doxorubicin

The Journal of biological chemistry, 2002-11, Vol.277 (46), p.44317-44326

2002

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Restriction of cisplatin induction of acute apoptosis to a subpopulation of cells in a three‐dimensional carcinoma culture model

International journal of cancer, 2009-11, Vol.125 (10), p.2450-2455

2009

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Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells

Molecular cancer therapeutics, 2009-01, Vol.8 (1), p.160-170

2009

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Target specificity and off-target effects as determinants of cancer drug efficacy

Expert opinion on drug metabolism & toxicology, 2008-03, Vol.4 (3), p.273-280

2008

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Reactive Oxygen Species and Mitochondria Mediate the Induction of Apoptosis in Human Hepatoma HepG2 Cells by the Rodent Peroxisome Proliferator and Hepatocarcinogen, Perfluorooctanoic Acid

Toxicology and applied pharmacology, 2001-05, Vol.173 (1), p.56-64

2001

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Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA

International journal of cancer, 2007-01, Vol.120 (1), p.175-180

2007

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Induction of endoplasmic reticulum stress by ellipticine plant alkaloids

Molecular cancer therapeutics, 2004-04, Vol.3 (4), p.489-497

2004

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Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II

BMC chemical biology, 2008-08, Vol.8 (2), p.2-2, Article 2

2008

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3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs

Molecular oncology, 2008-06, Vol.2 (1), p.94-101

2008

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Lysosomes and endoplasmic reticulum: Targets for improved, selective anticancer therapy

Drug resistance updates, 2005-08, Vol.8 (4), p.199-204

2005

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Mechanisms of action of DNA-damaging anticancer drugs in treatment of carcinomas: is acute apoptosis an "off-target" effect?

Mini reviews in medicinal chemistry, 2007-10, Vol.7 (10), p.1035

2007

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Determining tumor apoptosis and necrosis in patient serum using cytokeratin 18 as a biomarker

Cancer letters, 2004-10, Vol.214 (1), p.1-9

2004

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Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation

Carcinogenesis (New York), 2009-09, Vol.30 (9), p.1517-1527

2009

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Two Novel Adenovirus Vector Systems Permitting Regulated Protein Expression in Gene Transfer Experiments

Journal of Virology, 1998-10, Vol.72 (10), p.8358-8361

1998

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Is translational research compatible with preclinical publication strategies?

Radiation oncology (London, England), 2006-03, Vol.1 (1), p.4-4, Article 4

2006

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Interferon-α-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax

Oncogene, 2003-07, Vol.22 (29), p.4543-4556

2003

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Picropodophyllotoxin or podophyllotoxin does not induce cell death via insulin-like growth factor-I receptor

Cancer research (Chicago, Ill.), 2007-03, Vol.67 (6), p.2899; author reply 2899-2899

2007

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Cisplatin Induces Endoplasmic Reticulum Stress and Nucleus-independent Apoptotic Signaling

Induction of Lysosomal Membrane Permeabilization by Compounds That Activate p53-Independent Apoptosis

Potentiation of anti-cancer treatment by modulators of energy metabolism

3-bromopyruvate: Targets and outcomes

Cytokeratin-18 Is a Useful Serum Biomarker for Early Determination of Response of Breast Carcinomas to Chemotherapy

Differentiation between cell death modes using measurements of different soluble forms of extracellular cytokeratin 18

Potentiation of chemotherapeutic drugs by energy metabolism inhibitors 2‐deoxyglucose and etomoxir

Calpain-Mediated Bid Cleavage and Calpain-Independent Bak Modulation: Two Separate Pathways in Cisplatin-Induced Apoptosis

Activation of Bak, Bax, and BH3-only Proteins in the Apoptotic Response to Doxorubicin

Restriction of cisplatin induction of acute apoptosis to a subpopulation of cells in a three‐dimensional carcinoma culture model

Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells

Target specificity and off-target effects as determinants of cancer drug efficacy

Reactive Oxygen Species and Mitochondria Mediate the Induction of Apoptosis in Human Hepatoma HepG2 Cells by the Rodent Peroxisome Proliferator and Hepatocarcinogen, Perfluorooctanoic Acid

Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA

Induction of endoplasmic reticulum stress by ellipticine plant alkaloids

Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II

3-Bromopyruvate as inhibitor of tumour cell energy metabolism and chemopotentiator of platinum drugs

Lysosomes and endoplasmic reticulum: Targets for improved, selective anticancer therapy

Mechanisms of action of DNA-damaging anticancer drugs in treatment of carcinomas: is acute apoptosis an "off-target" effect?

Determining tumor apoptosis and necrosis in patient serum using cytokeratin 18 as a biomarker

Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation

Two Novel Adenovirus Vector Systems Permitting Regulated Protein Expression in Gene Transfer Experiments

Is translational research compatible with preclinical publication strategies?

Interferon-α-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax

Picropodophyllotoxin or podophyllotoxin does not induce cell death via insulin-like growth factor-I receptor

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