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Neuroblastoma: Molecular Pathogenesis and Therapy

Annual review of medicine, 2015-01, Vol.66 (1), p.49-63

2015

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PRMT5 activates AKT via methylation to promote tumor metastasis

Nature communications, 2022-07, Vol.13 (1), p.3955-3955, Article 3955

2022

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WIP1 phosphatase as a potential therapeutic target in neuroblastoma

PloS one, 2015-02, Vol.10 (2), p.e0115635-e0115635

2015

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CD114: A New Member of the Neural Crest‐Derived Cancer Stem Cell Marker Family

Journal of cellular biochemistry, 2017-02, Vol.118 (2), p.221-231

2017

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The role of histone demethylase KDM4B in Myc signaling in neuroblastoma

JNCI : Journal of the National Cancer Institute, 2015-06, Vol.107 (6), p.djv080-djv080

2015

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A Novel Druggable Dual-Specificity tYrosine-Regulated Kinase3/Calmodulin Kinase-like Vesicle-Associated Signaling Module with Therapeutic Implications in Neuroblastoma

Biomedicines, 2024-01, Vol.12 (1), p.197

2024

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MDM2-p53 interaction in paediatric solid tumours: preclinical rationale, biomarkers and resistance

Current drug targets, 2014-01, Vol.15 (1), p.114-123

2014

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A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma

PloS one, 2013-11, Vol.8 (11), p.e79843-e79843

2013

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MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma

Oncotarget, 2018-04, Vol.9 (29), p.20323-20338

2018

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Neuroblastoma pathogenesis: deregulation of embryonic neural crest development

Cell and tissue research, 2018-05, Vol.372 (2), p.245-262

2018

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The p53 Regulatory Gene MDM2 Is a Direct Transcriptional Target of MYCN in Neuroblastoma

Proceedings of the National Academy of Sciences - PNAS, 2005-01, Vol.102 (3), p.731-736

2005

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G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (13), p.4134-4146

2013

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MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death

Molecular cancer therapeutics, 2006-09, Vol.5 (9), p.2358-2365

2006

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A gold nanoparticle platform for the delivery of functional microRNAs into cancer cells

Biomaterials, 2013-01, Vol.34 (3), p.807-816

2013

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Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma

Oncotarget, 2015-11, Vol.6 (34), p.35247-35262

2015

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Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma

Angiogenesis (London), 2011-09, Vol.14 (3), p.255-266

2011

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G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation

Cancer research (Chicago, Ill.), 2015-06, Vol.75 (12), p.2566-2579

2015

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Blockade of Discoidin Domain Receptor Signaling with Sitravatinib Reveals DDR2 as a Mediator of Neuroblastoma Pathogenesis and Metastasis

Molecular cancer therapeutics, 2024-08, Vol.23 (8), p.1124-1138

2024

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Mdm2 Deficiency Suppresses MYCN-Driven Neuroblastoma Tumorigenesis In Vivo

Neoplasia (New York, N.Y.), 2009-08, Vol.11 (8), p.753-762

2009

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WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma

Cancer research (Chicago, Ill.), 2015-12, Vol.75 (23), p.5143-5154

2015

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MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cells

Cancer research (Chicago, Ill.), 2007-03, Vol.67 (6), p.2448-2455

2007

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G-CSF Is a Cancer Stem Cell-Specific Growth Factor-Response

Cancer research (Chicago, Ill.), 2015-09, Vol.75 (18), p.3992-3992

2015

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MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma

Cancer letters, 2015-09, Vol.366 (1), p.123-132

2015

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CD114 Expression Mediates Melanoma Tumor Cell Growth and Treatment Resistance

Anticancer research, 2015-07, Vol.35 (7), p.3787-3792

2015

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MDM2 as a Critical Effector of the MYCN Oncogene in Tumorigenesis

Cell cycle (Georgetown, Tex.), 2005-07, Vol.4 (7), p.857-860

2005

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Neuroblastoma: Molecular Pathogenesis and Therapy

PRMT5 activates AKT via methylation to promote tumor metastasis

WIP1 phosphatase as a potential therapeutic target in neuroblastoma

CD114: A New Member of the Neural Crest‐Derived Cancer Stem Cell Marker Family

The role of histone demethylase KDM4B in Myc signaling in neuroblastoma

A Novel Druggable Dual-Specificity tYrosine-Regulated Kinase3/Calmodulin Kinase-like Vesicle-Associated Signaling Module with Therapeutic Implications in Neuroblastoma

MDM2-p53 interaction in paediatric solid tumours: preclinical rationale, biomarkers and resistance

A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma

MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma

Neuroblastoma pathogenesis: deregulation of embryonic neural crest development

The p53 Regulatory Gene MDM2 Is a Direct Transcriptional Target of MYCN in Neuroblastoma

G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic

MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death

A gold nanoparticle platform for the delivery of functional microRNAs into cancer cells

Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma

Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma

G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation

Blockade of Discoidin Domain Receptor Signaling with Sitravatinib Reveals DDR2 as a Mediator of Neuroblastoma Pathogenesis and Metastasis

Mdm2 Deficiency Suppresses MYCN-Driven Neuroblastoma Tumorigenesis In Vivo

WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma

MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cells

G-CSF Is a Cancer Stem Cell-Specific Growth Factor-Response

MYCN-driven regulatory mechanisms controlling LIN28B in neuroblastoma

CD114 Expression Mediates Melanoma Tumor Cell Growth and Treatment Resistance

MDM2 as a Critical Effector of the MYCN Oncogene in Tumorigenesis

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