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Antitumor effects of eribulin depend on modulation of the tumor microenvironment by vascular remodeling in mouse models

Cancer science, 2017-11, Vol.108 (11), p.2273-2280

2017

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E6201 [(3S,4R,5Z,8S,9S,11E)-14-(ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-1 and MEK kinase-1: in vitro characterization of its anti-inflammatory and antihyperproliferative activities

The Journal of pharmacology and experimental therapeutics, 2009-11, Vol.331 (2), p.485

2009

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Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3155-3157

2010

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Discovery of an in vitro and in vivo potent resorcylic lactone analog of LL-Z1640-2 as anti-inflammatory lead, II

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3047-3049

2010

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Abstract 5927: Eribulin modulates tumor microenvironment through vascular remodeling for antitumor effect in multiple mouse xenograft models

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5927-5927

2017

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E6201, a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-1 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase-1: in vivo effects on cutaneous inflammatory responses by topical administration

The Journal of pharmacology and experimental therapeutics, 2010-10, Vol.335 (1), p.23

2010

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Characterization of sepsis pathogenesis using molecular biomarkers and drug treatments in the mouse CLP model (56.6)

The Journal of immunology (1950), 2011-04, Vol.186 (1_Supplement), p.56-56.6

2011

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A case of rectal gastrointestinal stromal tumor in an elderly patient who was successfully treated with imatinib mesylate with no significant adverse events

Gan to kagaku ryoho, 2014-01, Vol.41 (1), p.103

2014

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Discovery of an in vitro and in vivo potent resorcylic lactone analog of LL-Z1640-2 as anti-inflammatory lead

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3047-3049

2010

Volltextzugriff (PDF)

Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3155-3157

2010

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Atypical adenoma of the parathyroid gland: A case report

The Journal of the Japanese Society of Clinical Cytology, 1998/09/22, Vol.37(5), pp.500-504

1998

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A Case of Giant Brunner's Gland Hyperplasia in the Duodenum resected by Incising the Gastric Wall

The Japanese Journal of Gastroenterological Surgery, 2009/11/01, Vol.42(11), pp.1664-1669

2009

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3D-DIC-CT was useful to change from nonoperative management to laparotomy for hepatic injury (IIIb type): report of a case

Nihon Kyukyu Igakukai Zasshi, 2009/06/15, Vol.20(6), pp.325-330

2009

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An adult case of intussusception due to inverted Meckel's diverticulum accompanied by angiolipoma

Nippon Shokakibyo Gakkai Zasshi, 1996/04/05, Vol.93(4), pp.260-265

1996

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胃壁切開により切除しえた巨大十二指腸Brunner腺過形成の1例

日本消化器外科学会雑誌, 2009/11/01, Vol.42(11), pp.1664-1669

2009

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Stimulation of prostaglandin synthesis in cultured rat synovial cells by a factor derived from polymorphonuclear leukocytes

Prostaglandins, 1984-05, Vol.27 (5), p.697-709

1984

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開腹の決め手に3D-DIC-CTが有用であったIIIb型肝損傷の1例

日本救急医学会雑誌, 2009/06/15, Vol.20(6), pp.325-330

2009

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Macrofollicular variant of papillary thyroid carcinoma

Pathology international, 1998-06, Vol.48 (6), p.467-470

1998

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A novel orally active inhibitor of IL-1 generation: synthesis and structure-activity relationships of 3-(4-hydroxy-1-naphthalenyl)-2-propenoic acid derivatives

Journal of medicinal chemistry, 1992-12, Vol.35 (25), p.4665-4675

1992

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3-(5-Alkyl-4-hydroxy-3-methoxy-1-naphthalenyl)-2-methyl-2-propenoic acids as orally active inhibitors of IL-1 generation

Journal of medicinal chemistry, 1991-08, Vol.34 (8), p.2647-2649

1991

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A Factor Derived from Polymorphonuclear Leukocytes Enhances Interleukin‐1‐Induced Synovial Cell Collagenase and Prostaglandin E 2 Production in Rats

European journal of biochemistry, 1996-03, Vol.236 (2), p.517-522

1996

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A Factor Derived from Polymorphonuclear Leukocytes Enhances Interleukin‐1‐Induced Synovial Cell Collagenase and Prostaglandin E2 Production in Rats

European journal of biochemistry, 1996-03, Vol.236 (2), p.517-522

1996

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A case of primary malignant fibrous histiocytoma of the gallbladder and a review of the cases in Japan

Nippon Shokakibyo Gakkai Zasshi, 1998, Vol.95(2), pp.161-166

1998

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Comparison of Tl-201 Chloride and Ga-67 Citrate Scintigraphy in the Diagnosis of Thyroid Tumor: Concise Communication

The Journal of nuclear medicine (1978), 1982-03, Vol.23 (3), p.225-228

1982

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Macrofollicular variant of papillary thyroid carcinoma

Pathology International, 1998, Vol.48 (6), p.467-470

1998

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Antitumor effects of eribulin depend on modulation of the tumor microenvironment by vascular remodeling in mouse models

Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III

Discovery of an in vitro and in vivo potent resorcylic lactone analog of LL-Z1640-2 as anti-inflammatory lead, II

Abstract 5927: Eribulin modulates tumor microenvironment through vascular remodeling for antitumor effect in multiple mouse xenograft models

E6201, a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-1 and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase-1: in vivo effects on cutaneous inflammatory responses by topical administration

Characterization of sepsis pathogenesis using molecular biomarkers and drug treatments in the mouse CLP model (56.6)

A case of rectal gastrointestinal stromal tumor in an elderly patient who was successfully treated with imatinib mesylate with no significant adverse events

Discovery of an in vitro and in vivo potent resorcylic lactone analog of LL-Z1640-2 as anti-inflammatory lead

Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2

Atypical adenoma of the parathyroid gland: A case report

A Case of Giant Brunner's Gland Hyperplasia in the Duodenum resected by Incising the Gastric Wall

3D-DIC-CT was useful to change from nonoperative management to laparotomy for hepatic injury (IIIb type): report of a case

An adult case of intussusception due to inverted Meckel's diverticulum accompanied by angiolipoma

胃壁切開により切除しえた巨大十二指腸Brunner腺過形成の1例

Stimulation of prostaglandin synthesis in cultured rat synovial cells by a factor derived from polymorphonuclear leukocytes

開腹の決め手に3D-DIC-CTが有用であったIIIb型肝損傷の1例

Macrofollicular variant of papillary thyroid carcinoma

A novel orally active inhibitor of IL-1 generation: synthesis and structure-activity relationships of 3-(4-hydroxy-1-naphthalenyl)-2-propenoic acid derivatives

3-(5-Alkyl-4-hydroxy-3-methoxy-1-naphthalenyl)-2-methyl-2-propenoic acids as orally active inhibitors of IL-1 generation

A Factor Derived from Polymorphonuclear Leukocytes Enhances Interleukin‐1‐Induced Synovial Cell Collagenase and Prostaglandin E 2 Production in Rats

A Factor Derived from Polymorphonuclear Leukocytes Enhances Interleukin‐1‐Induced Synovial Cell Collagenase and Prostaglandin E2 Production in Rats

A case of primary malignant fibrous histiocytoma of the gallbladder and a review of the cases in Japan

Comparison of Tl-201 Chloride and Ga-67 Citrate Scintigraphy in the Diagnosis of Thyroid Tumor: Concise Communication

Macrofollicular variant of papillary thyroid carcinoma

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