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Therapeutic Destruction of Insulin Receptor Substrates for Cancer Treatment

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (14), p.4383-4394

2013

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EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

PLoS medicine, 2006-01, Vol.3 (1), p.e6

2006

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Inhibition of glioma growth by tumor-specific activation of double-stranded RNA-dependent protein kinase PKR

Nature biotechnology, 2002-09, Vol.20 (9), p.895-900

2002

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Nucleic acid-based therapeutics for glioblastoma

Anti-cancer agents in medicinal chemistry, 2011-10, Vol.11 (8), p.693-699

2011

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Correction: EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice

PLoS medicine, 2007-08, Vol.4 (8), p.e266

2007

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Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier

Pharmaceutical research, 2011-04, Vol.28 (4), p.731-741

2011

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EGFR-Homing dsRNA Activates Cancer-Targeted Immune Response and Eliminates Disseminated EGFR-Overexpressing Tumors in Mice

Clinical cancer research, 2011-03, Vol.17 (5), p.1033-1043

2011

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PSMA-targeted polyinosine/polycytosine vector induces prostate tumor regression and invokes an antitumor immune response in mice

Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (52), p.13655-13660

2017

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Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation

Molecular biology of the cell, 2016-03, Vol.27 (6), p.1026-1039

2016

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S101, an Inhibitor of Proliferating T Cells, Rescues Mice From Superantigen-Induced Shock

The Journal of infectious diseases, 2018-01, Vol.217 (2), p.288-297

2018

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PolyIC GE11 polyplex inhibits EGFR‐overexpressing tumors

IUBMB life, 2012-04, Vol.64 (4), p.324-330

2012

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Targeting the immune system to cancer

Polymers for advanced technologies, 2011-01, Vol.22 (1), p.99-102

2011

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Optimization of Liganded Polyethylenimine Polyethylene Glycol Vector for Nucleic Acid Delivery

Bioconjugate chemistry, 2014-09, Vol.25 (9), p.1644-1654

2014

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Abstract 5799: Novel nanoparticle technology targets the delivery of polyIC to EGFR overexpressing cancers and induces a multimodal anti-tumor response

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5799-5799

2024

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1170 EGFR-Ta:RNA: multimodal mechanism of action potentiates immune checkpoint inhibitor activity

Journal for immunotherapy of cancer, 2022-11, Vol.10 (Suppl 2), p.A1213-A1213

2022

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Human Interferon-γ mRNA Autoregulates Its Translation through a Pseudoknot that Activates the Interferon-Inducible Protein Kinase PKR

Cell, 2002-01, Vol.108 (2), p.221-232

2002

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Abstract B243: Targeting HER-2 positive breast cancer by inducing apoptosis and immune cell activation, overcoming trastuzumab resistance

Molecular cancer therapeutics, 2013-11, Vol.12 (11_Supplement), p.B243-B243

2013

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EGFR-homing dsRNA activates cancer targeted immune response and eliminates disseminated EGFR over-expressing tumors in mice

Clinical cancer research, 2010-12, Vol.17 (5), p.1033-1043

2010

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HER2-Targeted Polyinosine/Polycytosine Therapy Inhibits Tumor Growth and Modulates the Tumor Immune Microenvironment

Cancer immunology research, 2016-08, Vol.4 (8), p.688-697

2016

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Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier : Nucleic Acid Drug Delivery and Targeting

Pharmaceutical research, 2011, Vol.28 (4), p.731-741

2011

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EGFR-targeted Poly Inosine/Cytosine GE11 Polyplex Leads to Tumor Inhibition of EGFR Over-Expressing Tumors

IUBMB life, 2012-02, Vol.64 (4), p.324-330

2012

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Correction: EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

PLoS medicine, 2007-08, Vol.4 (8), p.1419

2007

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RNA molecules as anti-cancer agents

Seminars in cancer biology, 2004-08, Vol.14 (4), p.223-230

2004

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Tumor specific activation of PKR as a non-toxic modality of cancer treatment

Seminars in cancer biology, 2003-08, Vol.13 (4), p.309-314

2003

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Gene therapy for glioblastoma: future perspective for delivery systems and molecular targets

Cellular and molecular neurobiology, 2001-12, Vol.21 (6), p.645-656

2001

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Therapeutic Destruction of Insulin Receptor Substrates for Cancer Treatment

EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

Inhibition of glioma growth by tumor-specific activation of double-stranded RNA-dependent protein kinase PKR

Nucleic acid-based therapeutics for glioblastoma

Correction: EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice

Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier

EGFR-Homing dsRNA Activates Cancer-Targeted Immune Response and Eliminates Disseminated EGFR-Overexpressing Tumors in Mice

PSMA-targeted polyinosine/polycytosine vector induces prostate tumor regression and invokes an antitumor immune response in mice

Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation

S101, an Inhibitor of Proliferating T Cells, Rescues Mice From Superantigen-Induced Shock

PolyIC GE11 polyplex inhibits EGFR‐overexpressing tumors

Targeting the immune system to cancer

Optimization of Liganded Polyethylenimine Polyethylene Glycol Vector for Nucleic Acid Delivery

Abstract 5799: Novel nanoparticle technology targets the delivery of polyIC to EGFR overexpressing cancers and induces a multimodal anti-tumor response

1170 EGFR-Ta:RNA: multimodal mechanism of action potentiates immune checkpoint inhibitor activity

Human Interferon-γ mRNA Autoregulates Its Translation through a Pseudoknot that Activates the Interferon-Inducible Protein Kinase PKR

Abstract B243: Targeting HER-2 positive breast cancer by inducing apoptosis and immune cell activation, overcoming trastuzumab resistance

EGFR-homing dsRNA activates cancer targeted immune response and eliminates disseminated EGFR over-expressing tumors in mice

HER2-Targeted Polyinosine/Polycytosine Therapy Inhibits Tumor Growth and Modulates the Tumor Immune Microenvironment

Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier : Nucleic Acid Drug Delivery and Targeting

EGFR-targeted Poly Inosine/Cytosine GE11 Polyplex Leads to Tumor Inhibition of EGFR Over-Expressing Tumors

Correction: EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

RNA molecules as anti-cancer agents

Tumor specific activation of PKR as a non-toxic modality of cancer treatment

Gene therapy for glioblastoma: future perspective for delivery systems and molecular targets

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