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Hsp70 in cancer: back to the future

Oncogene, 2015-08, Vol.34 (32), p.4153-4161

2015

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The role of Bag3 in cell signaling

Journal of cellular biochemistry, 2022-01, Vol.123 (1), p.43-53

2022

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Resistance to TOP-1 Inhibitors: Good Old Drugs Still Can Surprise Us

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7233

2023

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Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

Oncogene, 2010-09, Vol.29 (37), p.5204-5213

2010

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Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis

Oncogene, 2011-06, Vol.30 (25), p.2836-2845

2011

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The Damaging Effect of Passenger Mutations on Cancer Progression

Cancer research (Chicago, Ill.), 2017-09, Vol.77 (18), p.4763-4772

2017

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A first order phase transition mechanism underlies protein aggregation in mammalian cells

eLife, 2019-02, Vol.8

2019

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Hsp70-Bag3 Interactions Regulate Cancer-Related Signaling Networks

Cancer research (Chicago, Ill.), 2014-09, Vol.74 (17), p.4731-4740

2014

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Hsp27 Modulates p53 Signaling and Suppresses Cellular Senescence

Cancer research (Chicago, Ill.), 2007-12, Vol.67 (24), p.11779-11788

2007

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Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer

Molecular cancer therapeutics, 2015-03, Vol.14 (3), p.642-648

2015

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Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis

Oncogene, 2015-10, Vol.34 (43), p.5460-5471

2015

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Hsp70–Bag3 Module Regulates Macrophage Motility and Tumor Infiltration via Transcription Factor LITAF and CSF1

Cancers, 2022-08, Vol.14 (17), p.4168

2022

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Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks

International journal of molecular sciences, 2023-05, Vol.24 (10), p.8717

2023

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A Potent Small Molecule Inhibits Polyglutamine Aggregation in Huntington's Disease Neurons and Suppresses Neurodegeneration in vivo

Proceedings of the National Academy of Sciences - PNAS, 2005-01, Vol.102 (3), p.892-897

2005

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Proteasome Failure Promotes Positioning of Lysosomes around the Aggresome via Local Block of Microtubule-Dependent Transport

Molecular and cellular biology, 2014-04, Vol.34 (7), p.1336-1348

2014

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Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR

Molecular and Cellular Biology, 2012-03, Vol.32 (5), p.929-940

2012

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Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells

Cancer research (Chicago, Ill.), 2016-10, Vol.76 (20), p.5926-5932

2016

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The Chaperone Function of hsp70 Is Required for Protection against Stress-Induced Apoptosis

Molecular and Cellular Biology, 2000-10, Vol.20 (19), p.7146-7159

2000

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A survey of immunohistochemical biomarkers for basal-like breast cancer against a gene expression profile gold standard

Modern pathology, 2013-11, Vol.26 (11), p.1438-1450

2013

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Cellular Defenses against Unfolded Proteins: A Cell Biologist Thinks about Neurodegenerative Diseases

Neuron, 2001, Vol.29 (1), p.15-32

2001

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ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

Oncogene, 2014-01, Vol.33 (2), p.212-224

2014

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Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration

Human molecular genetics, 2017-01, Vol.26 (2), p.305-319

2017

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Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity

Cell death & disease, 2020-04, Vol.11 (4), p.217, Article 217

2020

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Heat Shock Protein Hsp72 Controls Oncogene-Induced Senescence Pathways in Cancer Cells

Molecular and Cellular Biology, 2009-01, Vol.29 (2), p.559-569

2009

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A Cell Double-Barcoding System for Quantitative Evaluation of Primary Tumors and Metastasis in Animals That Uncovers Clonal-Specific Anti-Cancer Drug Effects

Cancers, 2022-03, Vol.14 (6), p.1381

2022

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Hsp70 in cancer: back to the future

The role of Bag3 in cell signaling

Resistance to TOP-1 Inhibitors: Good Old Drugs Still Can Surprise Us

Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

Heat shock protein Hsp72 plays an essential role in Her2-induced mammary tumorigenesis

The Damaging Effect of Passenger Mutations on Cancer Progression

A first order phase transition mechanism underlies protein aggregation in mammalian cells

Hsp70-Bag3 Interactions Regulate Cancer-Related Signaling Networks

Hsp27 Modulates p53 Signaling and Suppresses Cellular Senescence

Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer

Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis

Hsp70–Bag3 Module Regulates Macrophage Motility and Tumor Infiltration via Transcription Factor LITAF and CSF1

Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks

A Potent Small Molecule Inhibits Polyglutamine Aggregation in Huntington's Disease Neurons and Suppresses Neurodegeneration in vivo

Proteasome Failure Promotes Positioning of Lysosomes around the Aggresome via Local Block of Microtubule-Dependent Transport

Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR

Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells

The Chaperone Function of hsp70 Is Required for Protection against Stress-Induced Apoptosis

A survey of immunohistochemical biomarkers for basal-like breast cancer against a gene expression profile gold standard

Cellular Defenses against Unfolded Proteins: A Cell Biologist Thinks about Neurodegenerative Diseases

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration

Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity

Heat Shock Protein Hsp72 Controls Oncogene-Induced Senescence Pathways in Cancer Cells

A Cell Double-Barcoding System for Quantitative Evaluation of Primary Tumors and Metastasis in Animals That Uncovers Clonal-Specific Anti-Cancer Drug Effects

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