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A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease

Human molecular genetics, 2011-01, Vol.20 (2), p.211-222

2011

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Involvement of Phosphoinositide 3-Kinases in Neutrophil Activation and the Development of Acute Lung Injury

The Journal of immunology (1950), 2001-12, Vol.167 (11), p.6601-6608

2001

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Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia

The Journal of immunology (1950), 2001-01, Vol.166 (1), p.522-530

2001

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Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury

American journal of physiology. Lung cellular and molecular physiology, 2000-12, Vol.279 (6), p.1137-L1145

2000

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Biallelic somatic and germ line CCM1 truncating mutations in a cerebral cavernous malformation lesion

Stroke (1970), 2005-04, Vol.36 (4), p.872-874

2005

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Hemorrhage and resuscitation induce alterations in cytokine expression and the development of acute lung injury

American journal of respiratory cell and molecular biology, 1994-03, Vol.10 (3), p.290-297

1994

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Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein

The Journal of immunology (1950), 1999-07, Vol.163 (2), p.954-962

1999

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Phosphatidic acid signaling mediates lung cytokine expression and lung inflammatory injury after hemorrhage in mice

The Journal of experimental medicine, 1995-02, Vol.181 (2), p.569-575

1995

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Hemorrhage activates NF-kappa B in murine lung mononuclear cells in vivo

American journal of physiology. Lung cellular and molecular physiology, 1996-05, Vol.270 (5), p.729-L735

1996

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Effects of treatment with the 21-aminosteroid, U74389F, on pulmonary cytokine expression following hemorrhage and resuscitation

Critical care medicine, 1995-01, Vol.23 (1), p.132-139

1995

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Systemic blood loss affects NF-kappa B regulatory mechanisms in the lungs

American journal of physiology. Lung cellular and molecular physiology, 1997-07, Vol.273 (1), p.185-L192

1997

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Anti-transforming growth factor-beta monoclonal antibodies prevent lung injury in hemorrhaged mice

American journal of respiratory cell and molecular biology, 1994-09, Vol.11 (3), p.351-357

1994

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DNase I-hypersensitive sites and transcription factor-binding motifs within the mouse E beta meiotic recombination hot spot

Molecular and Cellular Biology, 1991-04, Vol.11 (4), p.1813-1819

1991

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EARLY RENAL ISCHEMIA, WITH OR WITHOUT REPERFUSION, ACTIVATES NFκB AND INCREASES TNF-α BIOACTIVITY IN THE KIDNEY

The Journal of urology, 2000, Vol.163 (4), p.1328-1332

2000

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Differential gene expression in human cerebrovascular malformations

Neurosurgery, 2003-02, Vol.52 (2), p.465-478

2003

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NF-κB REGULATORY MECHANISMS IN ALVEOLAR MACROPHAGES FROM PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME

Shock (Augusta, Ga.), 2000-02, Vol.13 (2), p.85-91

2000

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Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome

Critical care medicine, 1996-08, Vol.24 (8), p.1285-1292

1996

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Interactions between CBP, NF-κB, and CREB in the lungs after hemorrhage and endotoxemia

American journal of physiology. Lung cellular and molecular physiology, 2001-08, Vol.281 (2), p.L418-L426

2001

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Interleukin 18 Stimulates HIV Type 1 in Monocytic Cells

Proceedings of the National Academy of Sciences - PNAS, 1998-10, Vol.95 (21), p.12550-12555

1998

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Hemorrhage Activates Myocardial NFκB and Increases TNF-α in the Heart

Journal of molecular and cellular cardiology, 1997-10, Vol.29 (10), p.2849-2854

1997

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Effects of endogenous and exogenous catecholamines on LPS-induced neutrophil trafficking and activation

American journal of physiology. Lung cellular and molecular physiology, 1999-01, Vol.276 (1), p.1-L8

1999

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Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression

The Journal of clinical investigation, 1997-04, Vol.99 (7), p.1516-1524

1997

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Hyperoxia activates NF-kappaB and increases TNF-alpha and IFN-gamma gene expression in mouse pulmonary lymphocytes

The Journal of immunology (1950), 1996-11, Vol.157 (9), p.3902-3908

1996

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The mutation rate of the human mtDNA deletion mtDNA4977

American journal of human genetics, 1996-10, Vol.59 (4), p.772-780

1996

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Neutrophil Apoptosis in the Lung after Hemorrhage or Endotoxemia: Apoptosis and Migration Are Independent of IL-1β

Clinical immunology (Orlando, Fla.), 1999-05, Vol.91 (2), p.219-225

1999

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A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease

Involvement of Phosphoinositide 3-Kinases in Neutrophil Activation and the Development of Acute Lung Injury

Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia

Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury

Biallelic somatic and germ line CCM1 truncating mutations in a cerebral cavernous malformation lesion

Hemorrhage and resuscitation induce alterations in cytokine expression and the development of acute lung injury

Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein

Phosphatidic acid signaling mediates lung cytokine expression and lung inflammatory injury after hemorrhage in mice

Hemorrhage activates NF-kappa B in murine lung mononuclear cells in vivo

Effects of treatment with the 21-aminosteroid, U74389F, on pulmonary cytokine expression following hemorrhage and resuscitation

Systemic blood loss affects NF-kappa B regulatory mechanisms in the lungs

Anti-transforming growth factor-beta monoclonal antibodies prevent lung injury in hemorrhaged mice

DNase I-hypersensitive sites and transcription factor-binding motifs within the mouse E beta meiotic recombination hot spot

EARLY RENAL ISCHEMIA, WITH OR WITHOUT REPERFUSION, ACTIVATES NFκB AND INCREASES TNF-α BIOACTIVITY IN THE KIDNEY

Differential gene expression in human cerebrovascular malformations

NF-κB REGULATORY MECHANISMS IN ALVEOLAR MACROPHAGES FROM PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME

Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome

Interactions between CBP, NF-κB, and CREB in the lungs after hemorrhage and endotoxemia

Interleukin 18 Stimulates HIV Type 1 in Monocytic Cells

Hemorrhage Activates Myocardial NFκB and Increases TNF-α in the Heart

Effects of endogenous and exogenous catecholamines on LPS-induced neutrophil trafficking and activation

Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression

Hyperoxia activates NF-kappaB and increases TNF-alpha and IFN-gamma gene expression in mouse pulmonary lymphocytes

The mutation rate of the human mtDNA deletion mtDNA4977

Neutrophil Apoptosis in the Lung after Hemorrhage or Endotoxemia: Apoptosis and Migration Are Independent of IL-1β

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