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Role of cytokines in intervertebral disc degeneration: pain and disc content

Nature reviews. Rheumatology, 2014-01, Vol.10 (1), p.44-56

2014

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Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice

Nature communications, 2021-09, Vol.12 (1), p.5213-17, Article 5213

2021

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Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections

PloS one, 2019-08, Vol.14 (8), p.e0221012-e0221012

2019

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Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling

Autophagy, 2016-09, Vol.12 (9), p.1631-1646

2016

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Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus

PloS one, 2014-10, Vol.9 (10), p.e110768-e110768

2014

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Bicarbonate Recycling by HIF‐1–Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells

Journal of bone and mineral research, 2018-02, Vol.33 (2), p.338-355

2018

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Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death

Scientific reports, 2018-03, Vol.8 (1), p.4856-13, Article 4856

2018

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COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells

The Journal of biological chemistry, 2018-06, Vol.293 (23), p.8969-8981

2018

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The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection

Biomaterials, 2008-12, Vol.29 (35), p.4684-4690

2008

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Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: Implications for cell-based transplantation therapy

Spine (Philadelphia, Pa. 1976), 2004-12, Vol.29 (23), p.2627-2632

2004

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The Proteasome Inhibitor Carfilzomib Suppresses Parathyroid Hormone-induced Osteoclastogenesis through a RANKL-mediated Signaling Pathway

The Journal of biological chemistry, 2015-07, Vol.290 (27), p.16918-16928

2015

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Nucleus Pulposus Cells Upregulate PI3K/Akt and MEK/ERK Signaling Pathways Under Hypoxic Conditions and Resist Apoptosis Induced by Serum Withdrawal

Spine (Philadelphia, Pa. 1976), 2005-04, Vol.30 (8), p.882-889

2005

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GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc

JCI insight, 2023-04, Vol.8 (8)

2023

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Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression

Pediatric nephrology (Berlin, West), 2010-04, Vol.25 (4), p.633-642

2010

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Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus

Scientific reports, 2017-07, Vol.7 (1), p.4543-13, Article 4543

2017

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Autophagy: A New Phase in the Maturation of Growth Plate Chondrocytes Is Regulated by HIF, mTOR and AMP Kinase

Cells, tissues, organs, 2009-01, Vol.189 (1-4), p.88-92

2009

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Immobilized antibiotics to prevent orthopaedic implant infections

Advanced drug delivery reviews, 2012-09, Vol.64 (12), p.1165-1176

2012

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HIF‐1‐PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells

The FASEB journal, 2014-06, Vol.28 (6), p.2455-2465

2014

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HIF-1 Regulation of Chondrocyte Apoptosis: Induction of the Autophagic Pathway

Autophagy, 2007-05, Vol.3 (3), p.207-214

2007

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Autophagy in mineralizing tissues: Microenvironmental perspectives

Cell cycle (Georgetown, Tex.), 2009-02, Vol.8 (3), p.391-393

2009

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Microbubble cavitation restores Staphylococcus aureus antibiotic susceptibility in vitro and in a septic arthritis model

Communications biology, 2023-04, Vol.6 (1), p.425-425, Article 425

2023

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Glycosaminoglycan synthesis in the nucleus pulposus: Dysregulation and the pathogenesis of disc degeneration

Matrix biology, 2018-10, Vol.71-72, p.368-379

2018

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Matrix vesicles: Are they anchored exosomes?

Bone (New York, N.Y.), 2015-10, Vol.79, p.29-36

2015

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Controlled release of vancomycin from thin sol-gel films on implant surfaces successfully controls osteomyelitis

Journal of orthopaedic research, 2009-06, Vol.27 (6), p.701-709

2009

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Boning up on autophagy: The role of autophagy in skeletal biology

Autophagy, 2014-01, Vol.10 (1), p.7-19

2014

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Role of cytokines in intervertebral disc degeneration: pain and disc content

Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice

Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections

Hypoxia promotes noncanonical autophagy in nucleus pulposus cells independent of MTOR and HIF1A signaling

Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus

Bicarbonate Recycling by HIF‐1–Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells

Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death

COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells

The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection

Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: Implications for cell-based transplantation therapy

The Proteasome Inhibitor Carfilzomib Suppresses Parathyroid Hormone-induced Osteoclastogenesis through a RANKL-mediated Signaling Pathway

Nucleus Pulposus Cells Upregulate PI3K/Akt and MEK/ERK Signaling Pathways Under Hypoxic Conditions and Resist Apoptosis Induced by Serum Withdrawal

GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc

Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression

Lack of evidence for involvement of TonEBP and hyperosmotic stimulus in induction of autophagy in the nucleus pulposus

Autophagy: A New Phase in the Maturation of Growth Plate Chondrocytes Is Regulated by HIF, mTOR and AMP Kinase

Immobilized antibiotics to prevent orthopaedic implant infections

HIF‐1‐PHD2 axis controls expression of syndecan 4 in nucleus pulposus cells

HIF-1 Regulation of Chondrocyte Apoptosis: Induction of the Autophagic Pathway

Autophagy in mineralizing tissues: Microenvironmental perspectives

Microbubble cavitation restores Staphylococcus aureus antibiotic susceptibility in vitro and in a septic arthritis model

Glycosaminoglycan synthesis in the nucleus pulposus: Dysregulation and the pathogenesis of disc degeneration

Matrix vesicles: Are they anchored exosomes?

Controlled release of vancomycin from thin sol-gel films on implant surfaces successfully controls osteomyelitis

Boning up on autophagy: The role of autophagy in skeletal biology

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