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Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

Nature medicine, 2013-09, Vol.19 (9), p.1141-1146

2013

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Diabetes pathogenic mechanisms and potential new therapies based upon a novel target called TXNIP

Current opinion in endocrinology, diabetes, and obesity, 2018-04, Vol.25 (2), p.75-80

2018

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Intracellular Shuttling and Mitochondrial Function of Thioredoxin-interacting Protein

The Journal of biological chemistry, 2010-02, Vol.285 (6), p.3997-4005

2010

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Keeping tabs on fructose

eLife, 2016-10, Vol.5

Shalev, Anath

2016

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Metformin Use Is Associated With Reduced Mortality in a Diverse Population With COVID-19 and Diabetes

Frontiers in endocrinology (Lausanne), 2021-01, Vol.11, p.600439-600439

2021

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Minireview: Thioredoxin-Interacting Protein: Regulation and Function in the Pancreatic β-Cell

Molecular endocrinology (Baltimore, Md.), 2014-08, Vol.28 (8), p.1211-1220

Shalev, Anath

2014

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Glucose-stimulated Expression of Txnip Is Mediated by Carbohydrate Response Element-binding Protein, p300, and Histone H4 Acetylation in Pancreatic Beta Cells

The Journal of biological chemistry, 2009-06, Vol.284 (25), p.16898-16905

2009

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Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes

Nature communications, 2022-03, Vol.13 (1), p.1159-1159, Article 1159

2022

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miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function

Diabetes (New York, N.Y.), 2018-02, Vol.67 (2), p.256-264

2018

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MicroRNA-200 Is Induced by Thioredoxin-interacting Protein and Regulates Zeb1 Protein Signaling and Beta Cell Apoptosis

The Journal of biological chemistry, 2014-12, Vol.289 (52), p.36275-36283

2014

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Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Diabetes (New York, N.Y.), 2010-02, Vol.59 (2), p.440-447

2010

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Thioredoxin-Interacting Protein Stimulates Its Own Expression via a Positive Feedback Loop

Molecular endocrinology (Baltimore, Md.), 2014-05, Vol.28 (5), p.674-680

2014

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Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop

Molecular metabolism (Germany), 2016-12, Vol.5 (12), p.1208-1215

2016

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Thioredoxin-interacting Protein Promotes Islet Amyloid Polypeptide Expression through miR-124a and FoxA2

The Journal of biological chemistry, 2014-04, Vol.289 (17), p.11807-11815

2014

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Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

The FASEB journal, 2008-10, Vol.22 (10), p.3581-3594

2008

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Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein

American journal of physiology: endocrinology and metabolism, 2009-05, Vol.296 (5), p.E1133-E1139

2009

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From type 1 diabetes biology to therapy: The Human Islet Research Network

Molecular metabolism (Germany), 2021-12, Vol.54, p.101283-101283, Article 101283

2021

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What the BTBR/J mouse has taught us about diabetes and diabetic complications

iScience, 2023-07, Vol.26 (7), p.107036-107036, Article 107036

2023

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Calcium channel blockers act through nuclear factor Y to control transcription of key cardiac genes

Molecular pharmacology, 2012-09, Vol.82 (3), p.541-549

2012

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An approach for collaborative development of a federated biomedical knowledge graph-based question-answering system: Question-of-the-Month challenges

Journal of clinical and translational science, 2023-09, Vol.7 (1), p.e214-e214, Article e214

2023

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β-Cell MicroRNAs: Small but Powerful

Diabetes (New York, N.Y.), 2015-11, Vol.64 (11), p.3631-3644

2015

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Nitric oxide-dependent suppression of thioredoxin-interacting protein expression enhances thioredoxin activity

Arteriosclerosis, thrombosis, and vascular biology, 2006-12, Vol.26 (12), p.2666

2006

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A cis-Element in the 5′ Untranslated Region of the Preproinsulin mRNA (ppIGE) Is Required for Glucose Regulation of Proinsulin Translation

Cell metabolism, 2007-03, Vol.5 (3), p.221-227

2007

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Verapamil and beta cell function in adults with recent-onset type 1 diabetes

Nature medicine, 2018-08, Vol.24 (8), p.1108-1112

2018

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FOXO1 Competes with Carbohydrate Response Element-binding Protein (ChREBP) and Inhibits Thioredoxin-interacting Protein (TXNIP) Transcription in Pancreatic Beta Cells

The Journal of biological chemistry, 2013-08, Vol.288 (32), p.23194-23202

2013

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Thioredoxin-interacting protein regulates insulin transcription through microRNA-204

Diabetes pathogenic mechanisms and potential new therapies based upon a novel target called TXNIP

Intracellular Shuttling and Mitochondrial Function of Thioredoxin-interacting Protein

Keeping tabs on fructose

Metformin Use Is Associated With Reduced Mortality in a Diverse Population With COVID-19 and Diabetes

Minireview: Thioredoxin-Interacting Protein: Regulation and Function in the Pancreatic β-Cell

Glucose-stimulated Expression of Txnip Is Mediated by Carbohydrate Response Element-binding Protein, p300, and Histone H4 Acetylation in Pancreatic Beta Cells

Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes

miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function

MicroRNA-200 Is Induced by Thioredoxin-interacting Protein and Regulates Zeb1 Protein Signaling and Beta Cell Apoptosis

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Thioredoxin-Interacting Protein Stimulates Its Own Expression via a Positive Feedback Loop

Islet ChREBP-β is increased in diabetes and controls ChREBP-α and glucose-induced gene expression via a negative feedback loop

Thioredoxin-interacting Protein Promotes Islet Amyloid Polypeptide Expression through miR-124a and FoxA2

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein

From type 1 diabetes biology to therapy: The Human Islet Research Network

What the BTBR/J mouse has taught us about diabetes and diabetic complications

Calcium channel blockers act through nuclear factor Y to control transcription of key cardiac genes

An approach for collaborative development of a federated biomedical knowledge graph-based question-answering system: Question-of-the-Month challenges

β-Cell MicroRNAs: Small but Powerful

Nitric oxide-dependent suppression of thioredoxin-interacting protein expression enhances thioredoxin activity

A cis-Element in the 5′ Untranslated Region of the Preproinsulin mRNA (ppIGE) Is Required for Glucose Regulation of Proinsulin Translation

Verapamil and beta cell function in adults with recent-onset type 1 diabetes

FOXO1 Competes with Carbohydrate Response Element-binding Protein (ChREBP) and Inhibits Thioredoxin-interacting Protein (TXNIP) Transcription in Pancreatic Beta Cells

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