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A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids

Nature communications, 2021-01, Vol.12 (1), p.280-13, Article 280

2021

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Impact of Genetic Risk Factors for Alzheimer’s Disease on Brain Glucose Metabolism

Molecular neurobiology, 2021-06, Vol.58 (6), p.2608-2619

2021

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Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes

PloS one, 2016-09, Vol.11 (9), p.e0161969

2016

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Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

Neuron (Cambridge, Mass.), 2013-09, Vol.79 (6), p.1109-1122

2013

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Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes

Cell, 2015-06, Vol.161 (7), p.1592-1605

2015

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The schizophrenia risk gene product miR-137 alters presynaptic plasticity

Nature neuroscience, 2015-07, Vol.18 (7), p.1008-1016

2015

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CQTXNet: A Modified Xception Network with Attention Modules for Cover Song Identification

IEICE Transactions on Information and Systems, 2024/01/01, Vol.E107.D(1), pp.49-52

2024

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REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

Cell reports (Cambridge), 2019-01, Vol.26 (5), p.1112-1127.e9

2019

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Epigenetic Priming of Memory Updating during Reconsolidation to Attenuate Remote Fear Memories

Cell, 2014-01, Vol.156 (1-2), p.261-276

2014

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Trametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer’s disease

Experimental and Molecular Medicine, 2023, 55(0), , pp.2177-2189

2023

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ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells

Nature communications, 2023-12, Vol.14 (1), p.8463-8463, Article 8463

2023

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Author Correction: ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells

Nature communications, 2024-04, Vol.15 (1), p.3062-3062, Article 3062

2024

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PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4

Cell reports (Cambridge), 2020-10, Vol.33 (1), p.108224-108224, Article 108224

2020

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Restoration of Cathepsin D Level via L-Serine Attenuates PPA-Induced Lysosomal Dysfunction in Neuronal Cells

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10613

2022

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Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects

The Journal of neuroscience, 2017-09, Vol.37 (36), p.8655-8666

2017

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ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes

Cell reports (Cambridge), 2023-10, Vol.42 (10), p.113183-113183, Article 113183

2023

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The Perspectives of Early Diagnosis of Schizophrenia Through the Detection of Epigenomics-Based Biomarkers in iPSC-Derived Neurons

Frontiers in molecular neuroscience, 2021-11, Vol.14, p.756613-756613

2021

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Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β

Frontiers in immunology, 2023-06, Vol.14, p.1150940-1150940

2023

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Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (23), p.7291-7296

2015

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Genomics: New Light on Alzheimer's Disease Research

International journal of molecular sciences, 2018-11, Vol.19 (12), p.3771

2018

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Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice

Molecular brain, 2022-07, Vol.15 (1), p.1-63, Article 63

2022

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Regulation of N-type Voltage-Gated Calcium Channels and Presynaptic Function by Cyclin-Dependent Kinase 5

Neuron (Cambridge, Mass.), 2012-08, Vol.75 (4), p.675-687

2012

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TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice

Journal of Alzheimer's disease, 2017-01, Vol.56 (1), p.335-349

2017

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Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins

The Journal of neuroscience, 2010-10, Vol.30 (42), p.14134-14144

2010

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Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment

The Journal of neuroscience, 2015-02, Vol.35 (6), p.2372-2383

2015

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A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids

Impact of Genetic Risk Factors for Alzheimer’s Disease on Brain Glucose Metabolism

Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes

Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes

The schizophrenia risk gene product miR-137 alters presynaptic plasticity

CQTXNet: A Modified Xception Network with Attention Modules for Cover Song Identification

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

Epigenetic Priming of Memory Updating during Reconsolidation to Attenuate Remote Fear Memories

Trametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer’s disease

ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells

Author Correction: ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells

PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4

Restoration of Cathepsin D Level via L-Serine Attenuates PPA-Induced Lysosomal Dysfunction in Neuronal Cells

Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects

ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes

The Perspectives of Early Diagnosis of Schizophrenia Through the Detection of Epigenomics-Based Biomarkers in iPSC-Derived Neurons

Lomerizine inhibits LPS-mediated neuroinflammation and tau hyperphosphorylation by modulating NLRP3, DYRK1A, and GSK3α/β

Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway

Genomics: New Light on Alzheimer's Disease Research

Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice

Regulation of N-type Voltage-Gated Calcium Channels and Presynaptic Function by Cyclin-Dependent Kinase 5

TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice

Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins

Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment

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