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The TNF Paradox in Cancer Progression and Immunotherapy

Frontiers in immunology, 2019-07, Vol.10, p.1818-1818

2019

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Combining Nivolumab and Ipilimumab with Infliximab or Certolizumab in Patients with Advanced Melanoma: First Results of a Phase Ib Clinical Trial

Clinical cancer research, 2021-02, Vol.27 (4), p.1037-1047

2021

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Lipid metabolic Reprogramming: Role in Melanoma Progression and Therapeutic Perspectives

Cancers, 2020-10, Vol.12 (11), p.3147

2020

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Blocking Tumor Necrosis Factor α Enhances CD8 T-cell-Dependent Immunity in Experimental Melanoma

Cancer research (Chicago, Ill.), 2015-07, Vol.75 (13), p.2619-2628

2015

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A fluorogenic substrate for the detection of lipid amidases in intact cells

Journal of lipid research, 2024-03, Vol.65 (3), p.100520-100520, Article 100520

2024

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Morniga-G, a T/Tn-Specific Lectin, Induces Leukemic Cell Death via Caspase and DR5 Receptor-Dependent Pathways

International journal of molecular sciences, 2019-01, Vol.20 (1), p.230

2019

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IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis

PloS one, 2009-11, Vol.4 (11), p.e7929-e7929

2009

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Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas

Molecular cancer therapeutics, 2019-02, Vol.18 (2), p.289-300

2019

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OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals

Experimental cell research, 2007-10, Vol.313 (17), p.3800-3808

2007

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New Insights into the Role of Sphingolipid Metabolism in Melanoma

Cells (Basel, Switzerland), 2020-08, Vol.9 (9), p.1967

2020

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TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma

Nature communications, 2017-12, Vol.8 (1), p.2256-2256, Article 2256

2017

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Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma

Oncotarget, 2016-11, Vol.7 (44), p.71873-71886

2016

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Sphingolipids as modulators of cancer cell death: Potential therapeutic targets

Biochimica et biophysica acta, 2006-12, Vol.1758 (12), p.2104-2120

2006

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Anti-TNF, a magic bullet in cancer immunotherapy?

Journal for immunotherapy of cancer, 2019-11, Vol.7 (1), p.303-303, Article 303

2019

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S1P: the elixir of life for naive T cells

Cellular & molecular immunology, 2018-07, Vol.15 (7), p.657-659

2018

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Method to Measure Sphingomyelin Synthase Activity Changes in Response to CD95L

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1557, p.207

2017

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P rostatitis, other genitourinary infections and prostate cancer risk: I nfluence of non‐steroidal anti‐inflammatory drugs? R esults from the EPICAP study

International journal of cancer, 2018-10, Vol.143 (7), p.1644-1651

2018

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Combining TNF blockade with immune checkpoint inhibitors in patients with cancer

Nature reviews. Rheumatology, 2021-09, Vol.17 (9), p.577-577

2021

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Liquid Chromatography-High Resolution Mass Spectrometry Method to Study Sphingolipid Metabolism Changes in Response to CD95L

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1557, p.213

2017

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Cleavage and Cytoplasmic Relocalization of Histone Deacetylase 3 Are Important for Apoptosis Progression

Molecular and Cellular Biology, 2007-01, Vol.27 (2), p.554-567

2007

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Redistribution of CD95 into the lipid rafts to treat cancer cells?

Recent patents on anti-cancer drug discovery, 2010-01, Vol.5 (1), p.22-28

2010

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Caspase-10-dependent cell death in Fas/CD95 signalling is not abrogated by caspase inhibitor zVAD-fmk

PloS one, 2010-10, Vol.5 (10), p.e13638

2010

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Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1

Nature communications, 2020-01, Vol.11 (1), p.437-437, Article 437

2020

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FAN (factor associated with neutral sphingomyelinase activation), a moonlighting protein in TNF-R1 signaling

Journal of leukocyte biology, 2010-11, Vol.88 (5), p.897-903

2010

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Regulation of death and growth signals at the plasma membrane by sphingomyelin synthesis: implications for hematological malignancies

Recent patents on anti-cancer drug discovery, 2011-09, Vol.6 (3), p.324-333

2011

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The TNF Paradox in Cancer Progression and Immunotherapy

Combining Nivolumab and Ipilimumab with Infliximab or Certolizumab in Patients with Advanced Melanoma: First Results of a Phase Ib Clinical Trial

Lipid metabolic Reprogramming: Role in Melanoma Progression and Therapeutic Perspectives

Blocking Tumor Necrosis Factor α Enhances CD8 T-cell-Dependent Immunity in Experimental Melanoma

A fluorogenic substrate for the detection of lipid amidases in intact cells

Morniga-G, a T/Tn-Specific Lectin, Induces Leukemic Cell Death via Caspase and DR5 Receptor-Dependent Pathways

IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis

Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas

OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals

New Insights into the Role of Sphingolipid Metabolism in Melanoma

TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma

Downregulation of sphingosine kinase-1 induces protective tumor immunity by promoting M1 macrophage response in melanoma

Sphingolipids as modulators of cancer cell death: Potential therapeutic targets

Anti-TNF, a magic bullet in cancer immunotherapy?

S1P: the elixir of life for naive T cells

Method to Measure Sphingomyelin Synthase Activity Changes in Response to CD95L

P rostatitis, other genitourinary infections and prostate cancer risk: I nfluence of non‐steroidal anti‐inflammatory drugs? R esults from the EPICAP study

Combining TNF blockade with immune checkpoint inhibitors in patients with cancer

Liquid Chromatography-High Resolution Mass Spectrometry Method to Study Sphingolipid Metabolism Changes in Response to CD95L

Cleavage and Cytoplasmic Relocalization of Histone Deacetylase 3 Are Important for Apoptosis Progression

Redistribution of CD95 into the lipid rafts to treat cancer cells?

Caspase-10-dependent cell death in Fas/CD95 signalling is not abrogated by caspase inhibitor zVAD-fmk

Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1

FAN (factor associated with neutral sphingomyelinase activation), a moonlighting protein in TNF-R1 signaling

Regulation of death and growth signals at the plasma membrane by sphingomyelin synthesis: implications for hematological malignancies

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