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MYC degradation

Cold Spring Harbor perspectives in medicine, 2014-03, Vol.4 (3), p.a014365-a014365

2014

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The Life Cycle of C-Myc: From Synthesis to Degradation

Cell cycle (Georgetown, Tex.), 2004-09, Vol.3 (9), p.1131-1135

Sears, Rosalie C.

2004

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A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

Cancer discovery, 2019-05, Vol.9 (5), p.617-627

2019

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Serum Biomarker Signature-Based Liquid Biopsy for Diagnosis of Early-Stage Pancreatic Cancer

Journal of clinical oncology, 2018-10, Vol.36 (28), p.2887-2894

2018

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nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (12), p.3734-3739

2015

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Fragile X Mental Retardation Protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry

Neurobiology of disease, 2019-07, Vol.127, p.53-64

2019

Volltextzugriff (PDF)

Density-transition based electron injector for laser driven wakefield accelerators

Physical review special topics. PRST-AB. Accelerators and beams, 2010-09, Vol.13 (9), p.091301, Article 091301

2010

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Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

The Journal of clinical investigation, 2017-06, Vol.127 (6), p.2081-2090

2017

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Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Nature communications, 2018-09, Vol.9 (1), p.3815-17, Article 3815

2018

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Protein Phosphatase 2A Regulatory Subunit B56α Associates with c-Myc and Negatively Regulates c-Myc Accumulation

Molecular and Cellular Biology, 2006-04, Vol.26 (7), p.2832-2844

2006

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Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.9157-9162

2014

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The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis

Mucosal immunology, 2017-03, Vol.10 (2), p.421-433

2017

Volltextzugriff (PDF)

Unraveling MYC's Role in Orchestrating Tumor Intrinsic and Tumor Microenvironment Interactions Driving Tumorigenesis and Drug Resistance

Pathophysiology (Amsterdam), 2023-09, Vol.30 (3), p.400-419

2023

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Select Stabilization of a Tumor-Suppressive PP2A Heterotrimer

Trends in pharmacological sciences (Regular ed.), 2020-09, Vol.41 (9), p.595-597

2020

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Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals

Genes & development, 2018-11, Vol.32 (21-22), p.1398-1419

2018

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Few-cycle driven relativistically oscillating plasma mirrors: a source of intense isolated attosecond pulses

Physical review letters, 2012-06, Vol.108 (23), p.235003-235003, Article 235003

2012

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The ubiquitin-specific protease USP36 is a conserved histone H2B deubiquitinase

Biochemical and biophysical research communications, 2018-01, Vol.495 (3), p.2363-2368

2018

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The Emerging Clinical Importance of Non-O157 Shiga Toxin—Producing Escherichia coli

Clinical infectious diseases, 2006-12, Vol.43 (12), p.1587-1595

2006

Volltextzugriff (PDF)

Phosphorylation Regulates c-Myc's Oncogenic Activity in the Mammary Gland

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (3), p.925-936

2011

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Fragile X Mental Retardation Protein Regulates Activity-Dependent Membrane Trafficking and Trans -Synaptic Signaling Mediating Synaptic Remodeling

Frontiers in molecular neuroscience, 2018-01, Vol.10, p.440-440

2018

Volltextzugriff (PDF)

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Nature communications, 2017-11, Vol.8 (1), p.1728-12, Article 1728

2017

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Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis

Molecular and Cellular Biology, 2013-08, Vol.33 (15), p.2930-2949

2013

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AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity

Nature (London), 2021-04, Vol.592 (7856), p.799-803

2021

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Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy

Frontiers in oncology, 2021-06, Vol.11, p.679445-679445

2021

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MYC degradation

The Life Cycle of C-Myc: From Synthesis to Degradation

A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

Serum Biomarker Signature-Based Liquid Biopsy for Diagnosis of Early-Stage Pancreatic Cancer

nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc

Fragile X Mental Retardation Protein positively regulates PKA anchor Rugose and PKA activity to control actin assembly in learning/memory circuitry

Density-transition based electron injector for laser driven wakefield accelerators

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Protein Phosphatase 2A Regulatory Subunit B56α Associates with c-Myc and Negatively Regulates c-Myc Accumulation

Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis

Unraveling MYC's Role in Orchestrating Tumor Intrinsic and Tumor Microenvironment Interactions Driving Tumorigenesis and Drug Resistance

Select Stabilization of a Tumor-Suppressive PP2A Heterotrimer

Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals

Few-cycle driven relativistically oscillating plasma mirrors: a source of intense isolated attosecond pulses

The ubiquitin-specific protease USP36 is a conserved histone H2B deubiquitinase

The Emerging Clinical Importance of Non-O157 Shiga Toxin—Producing Escherichia coli

Phosphorylation Regulates c-Myc's Oncogenic Activity in the Mammary Gland

Fragile X Mental Retardation Protein Regulates Activity-Dependent Membrane Trafficking and Trans -Synaptic Signaling Mediating Synaptic Remodeling

MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance

Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis

AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity

Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups

Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy

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