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Controllable protein phase separation and modular recruitment to form responsive membraneless organelles

Nature communications, 2018-07, Vol.9 (1), p.2985-12, Article 2985

2018

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Brain-Penetrating Nanoparticles Improve Paclitaxel Efficacy in Malignant Glioma Following Local Administration

ACS nano, 2014-10, Vol.8 (10), p.10655-10664

2014

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Particle tracking in drug and gene delivery research: State-of-the-art applications and methods

Advanced drug delivery reviews, 2015-08, Vol.91, p.70-91

2015

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Directly light-regulated binding of RGS-LOV photoreceptors to anionic membrane phospholipids

Proceedings of the National Academy of Sciences - PNAS, 2018-08, Vol.115 (33), p.E7720-E7727

2018

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Surface tension and viscosity of protein condensates quantified by micropipette aspiration

Biophysical reports, 2021-09, Vol.1 (1), p.100011, Article 100011

2021

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SPLIT: Stable Protein Coacervation Using a Light Induced Transition

ACS synthetic biology, 2020-03, Vol.9 (3), p.500-507

2020

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Optochemical Control of Protein Localization and Activity within Cell-like Compartments

Biochemistry (Easton), 2018-05, Vol.57 (18), p.2590-2596

2018

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Particle-Tracking Microrheology Using Micro-Optical Coherence Tomography

Biophysical journal, 2016-09, Vol.111 (5), p.1053-1063

2016

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Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: Demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI)

Nanomedicine, 2015-02, Vol.11 (2), p.401-405

2015

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Nanoparticle diffusion in respiratory mucus from humans without lung disease

Biomaterials, 2013-04, Vol.34 (13), p.3439-3446

2013

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Amphiphilic proteins coassemble into multiphasic condensates and act as biomolecular surfactants

Proceedings of the National Academy of Sciences - PNAS, 2021-12, Vol.118 (51)

2021

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Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior

Proceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (21), p.11421-11431

2020

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Designer membraneless organelles sequester native factors for control of cell behavior

Nature chemical biology, 2021-09, Vol.17 (9), p.998

2021

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Expanding the molecular language of protein liquid–liquid phase separation

Nature chemistry, 2024-03, Vol.16 (7), p.1113-1124

2024

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Biomolecular Condensates: Sequence Determinants of Phase Separation, Microstructural Organization, Enzymatic Activity, and Material Properties

The journal of physical chemistry. B, 2021-04, Vol.125 (14), p.3441-3451

2021

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Elucidating residue level contributions to phase separation using a model polypeptide

Biophysical journal, 2023-02, Vol.122 (3), p.206a-206a

2023

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Enzyme purification and sustained enzyme activity for pharmaceutical biocatalysis by fusion with phase‐separating intrinsically disordered protein

Biotechnology and bioengineering, 2024-07, Vol.121 (10), p.3155-3168

2024

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Revealing nanoscale structure and interfaces of protein and polymer condensates via cryo-electron microscopy

Nanoscale, 2024-09, Vol.16 (35), p.16706-16717

2024

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Incorporation and Assembly of a Light-Emitting Enzymatic Reaction into Model Protein Condensates: Published as part of the Biochemistry virtual special issue “Protein Condensates”

Biochemistry (Easton), 2021-10, Vol.60 (42), p.3137-3151

2021

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Incorporation and Assembly of a Light-Emitting Enzymatic Reaction into Model Protein Condensates

Biochemistry (Easton), 2021-10, Vol.60 (42), p.3137-3151

2021

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Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

Science advances, 2017-04, Vol.3 (4), p.e1601556-e1601556

2017

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A Functional Anatomic Defect of the Cystic Fibrosis Airway

American journal of respiratory and critical care medicine, 2014-08, Vol.190 (4), p.421-432

2014

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Photoactivatable fluorescent probes reveal heterogeneous nanoparticle permeation through biological gels at multiple scales

Journal of controlled release, 2017-08, Vol.260 (C), p.124-133

2017

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Overcoming the Cystic Fibrosis Sputum Barrier to Leading Adeno-associated Virus Gene Therapy Vectors

Molecular therapy, 2014-08, Vol.22 (8), p.1484-1493

2014

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Use of Single-Site-Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers

Angewandte Chemie (International ed.), 2013-04, Vol.52 (14), p.3985-3988

International ed. in English, 2013

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Controllable protein phase separation and modular recruitment to form responsive membraneless organelles

Brain-Penetrating Nanoparticles Improve Paclitaxel Efficacy in Malignant Glioma Following Local Administration

Particle tracking in drug and gene delivery research: State-of-the-art applications and methods

Directly light-regulated binding of RGS-LOV photoreceptors to anionic membrane phospholipids

Surface tension and viscosity of protein condensates quantified by micropipette aspiration

SPLIT: Stable Protein Coacervation Using a Light Induced Transition

Optochemical Control of Protein Localization and Activity within Cell-like Compartments

Particle-Tracking Microrheology Using Micro-Optical Coherence Tomography

Liposome-based mucus-penetrating particles (MPP) for mucosal theranostics: Demonstration of diamagnetic chemical exchange saturation transfer (diaCEST) magnetic resonance imaging (MRI)

Nanoparticle diffusion in respiratory mucus from humans without lung disease

Amphiphilic proteins coassemble into multiphasic condensates and act as biomolecular surfactants

Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior

Designer membraneless organelles sequester native factors for control of cell behavior

Expanding the molecular language of protein liquid–liquid phase separation

Biomolecular Condensates: Sequence Determinants of Phase Separation, Microstructural Organization, Enzymatic Activity, and Material Properties

Elucidating residue level contributions to phase separation using a model polypeptide

Enzyme purification and sustained enzyme activity for pharmaceutical biocatalysis by fusion with phase‐separating intrinsically disordered protein

Revealing nanoscale structure and interfaces of protein and polymer condensates via cryo-electron microscopy

Incorporation and Assembly of a Light-Emitting Enzymatic Reaction into Model Protein Condensates: Published as part of the Biochemistry virtual special issue “Protein Condensates”

Incorporation and Assembly of a Light-Emitting Enzymatic Reaction into Model Protein Condensates

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

A Functional Anatomic Defect of the Cystic Fibrosis Airway

Photoactivatable fluorescent probes reveal heterogeneous nanoparticle permeation through biological gels at multiple scales

Overcoming the Cystic Fibrosis Sputum Barrier to Leading Adeno-associated Virus Gene Therapy Vectors

Use of Single-Site-Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers

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