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Derivation of Rapamycin: Adventures in Natural Product Chemistry

Chimia, 2019-08, Vol.73 (7-8), p.581

2019

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Myocardial late enhancement in contrast-enhanced cardiac MRI: distinction between infarction scar and non-infarction-related disease

American journal of roentgenology (1976), 2005-05, Vol.184 (5), p.1420

2005

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Protein Kinase C Inhibitor Sotrastaurin Selectively Inhibits the Growth of CD79 Mutant Diffuse Large B-Cell Lymphomas

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (7), p.2643-2653

2011

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Detection and characterization of intracardiac thrombi on MR imaging

American journal of roentgenology (1976), 2002-12, Vol.179 (6), p.1539

2002

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The Immunosuppressive Macrolide RAD Inhibits Growth of Human Epstein-Barr Virus-Transformed B Lymphocytes in vitro and in vivo: A Potential Approach to Prevention and Treatment of Posttransplant Lymphoproliferative Disorders

Proceedings of the National Academy of Sciences - PNAS, 2000-04, Vol.97 (8), p.4285-4290

2000

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The macrolide everolimus forms an unusual metabolite in animals and humans: identification of a phosphocholine ester

Drug metabolism and disposition, 2008-08, Vol.36 (8), p.1457

2008

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Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp. A92-308110: I. Taxonomy, Fermentation, Isolation and Biological Activity

The Journal of Antibiotics, 1999/05/25, Vol.52(5), pp.466-473

1999

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Indolyl-naphthyl-maleimides as potent and selective inhibitors of protein kinase C-α/β

Bioorganic & medicinal chemistry letters, 2017-02, Vol.27 (4), p.781-786

2017

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Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension

Bioorganic & medicinal chemistry letters, 2014-10, Vol.24 (20), p.4812-4817

2014

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Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses

Transplantation, 2003-05, Vol.75 (10), p.1710

2003

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SDZ RAD, a new rapamycin derivative: pharmacological properties in vitro and in vivo

Transplantation, 1997-07, Vol.64 (1), p.36

1997

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2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (24), p.7367-7372

2011

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Efficacy and safety of ABI793, a novel human anti-human CD154 monoclonal antibody, in cynomolgus monkey renal allotransplantation

Transplantation, 2004-03, Vol.77 (5), p.717

2004

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Antascomicins A, B, C, D and E Novel FKBP12 Binding Compounds from a Micromonospora Strain

The Journal of Antibiotics, 1996/03/25, Vol.49(3), pp.230-233

1996

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SDZ RAD, a new rapamycin derivative: synergism with cyclosporine

Transplantation, 1997-07, Vol.64 (1), p.32

1997

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Monotherapy with the novel human anti-CD154 monoclonal antibody ABI793 in rhesus monkey renal transplantation model

Transplantation, 2004-03, Vol.77 (6), p.914

2004

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Sanglifehrin A, a Novel Cyclophilin-Binding Compound Showing Immunosuppressive Activity with a New Mechanism of Action

The Journal of immunology (1950), 2001-06, Vol.166 (12), p.7165-7171

2001

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Oral efficacy of the macrolide immunosuppressant SDZ RAD and of cyclosporine microemulsion in cynomolgus monkey kidney allotransplantation

Transplantation, 2000-03, Vol.69 (5), p.737

2000

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Cymbimicin A and B, Two Novel Cyclophilin-binding Structures Isolated from Actinomycetes

The Journal of Antibiotics, 1997/11/25, Vol.50(11), pp.893-899

1997

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New Derivatives of Ascomycin with Modifications in the Amino Acid Region - Synthesis and Biological Activities, and X-Ray Crystal Structure of 5,6-Dehydroascomycin

Helvetica chimica acta, 2009-05, Vol.92 (5), p.839-889

2009

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Successful treatment of acute, ongoing rat lung allograft rejection with the novel immunosuppressant SDZ-RAD

The Annals of thoracic surgery, 2000-03, Vol.69 (3), p.904-909

2000

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A Locally Active Antiinflammatory Macrolide (MLD987) for Inhalation Therapy of Asthma

Journal of medicinal chemistry, 2004-09, Vol.47 (20), p.4950-4957

2004

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Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency

Cell, 1986-09, Vol.46 (7), p.963-972

1986

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Growth of human tumors in immune-deficient scid mice and nude mice

Current topics in microbiology and immunology, 1989, Vol.152, p.259

1989

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Preparation and immunosuppressive activity of 32-( O)-acylated and 32-( O)-thioacylated analogues of ascomycin

Bioorganic & medicinal chemistry letters, 1999-01, Vol.9 (2), p.227-232

1999

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Derivation of Rapamycin: Adventures in Natural Product Chemistry

Myocardial late enhancement in contrast-enhanced cardiac MRI: distinction between infarction scar and non-infarction-related disease

Protein Kinase C Inhibitor Sotrastaurin Selectively Inhibits the Growth of CD79 Mutant Diffuse Large B-Cell Lymphomas

Detection and characterization of intracardiac thrombi on MR imaging

The Immunosuppressive Macrolide RAD Inhibits Growth of Human Epstein-Barr Virus-Transformed B Lymphocytes in vitro and in vivo: A Potential Approach to Prevention and Treatment of Posttransplant Lymphoproliferative Disorders

The macrolide everolimus forms an unusual metabolite in animals and humans: identification of a phosphocholine ester

Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp. A92-308110: I. Taxonomy, Fermentation, Isolation and Biological Activity

Indolyl-naphthyl-maleimides as potent and selective inhibitors of protein kinase C-α/β

Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension

Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses

SDZ RAD, a new rapamycin derivative: pharmacological properties in vitro and in vivo

2,6-Naphthyridines as potent and selective inhibitors of the novel protein kinase C isozymes

Efficacy and safety of ABI793, a novel human anti-human CD154 monoclonal antibody, in cynomolgus monkey renal allotransplantation

Antascomicins A, B, C, D and E Novel FKBP12 Binding Compounds from a Micromonospora Strain

SDZ RAD, a new rapamycin derivative: synergism with cyclosporine

Monotherapy with the novel human anti-CD154 monoclonal antibody ABI793 in rhesus monkey renal transplantation model

Sanglifehrin A, a Novel Cyclophilin-Binding Compound Showing Immunosuppressive Activity with a New Mechanism of Action

Oral efficacy of the macrolide immunosuppressant SDZ RAD and of cyclosporine microemulsion in cynomolgus monkey kidney allotransplantation

Cymbimicin A and B, Two Novel Cyclophilin-binding Structures Isolated from Actinomycetes

New Derivatives of Ascomycin with Modifications in the Amino Acid Region - Synthesis and Biological Activities, and X-Ray Crystal Structure of 5,6-Dehydroascomycin

Successful treatment of acute, ongoing rat lung allograft rejection with the novel immunosuppressant SDZ-RAD

A Locally Active Antiinflammatory Macrolide (MLD987) for Inhalation Therapy of Asthma

Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency

Growth of human tumors in immune-deficient scid mice and nude mice

Preparation and immunosuppressive activity of 32-( O)-acylated and 32-( O)-thioacylated analogues of ascomycin

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