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Pharmacogenetic Pathway Analysis of Docetaxel Elimination

Clinical pharmacology and therapeutics, 2009-02, Vol.85 (2), p.155-163

2009

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Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content

The pharmacogenomics journal, 2016-08, Vol.16 (4), p.375-387

2016

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Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism

Drug metabolism and disposition, 2016-03, Vol.44 (3), p.343-351

2016

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Influence of Solute Carriers on the Pharmacokinetics of CYP3A4 Probes

Clinical pharmacology and therapeutics, 2008-12, Vol.84 (6), p.704-709

2008

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Statistical Orbit Determination

1, 2004

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6′,7′-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein

Clinical pharmacology and therapeutics, 1999-03, Vol.65 (3), p.237-244

1999

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Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics

Current drug metabolism, 2005-08, Vol.6 (4), p.369

2005

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PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators

Toxicology and applied pharmacology, 2004-09, Vol.199 (3), p.251-265

2004

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Identification of functionally variant MDR1 alleles among European Americans and African Americans

Clinical pharmacology and therapeutics, 2001-08, Vol.70 (2), p.189-199

2001

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Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

The Journal of biological chemistry, 2004-05, Vol.279 (21), p.22250-22257

2004

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Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells

Molecular pharmacology, 1996-02, Vol.49 (2), p.311

1996

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Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines

The pharmacogenomics journal, 2017-03, Vol.17 (2), p.137-145

2017

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Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms

The Journal of pharmacology and experimental therapeutics, 1995-11, Vol.275 (2), p.1011

1995

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Fetal MR lung volumetry in congenital diaphragmatic hernia (CDH): prediction of clinical outcome and the need for extracorporeal membrane oxygenation (ECMO)

Klinische Padiatrie, 2009-09, Vol.221 (5), p.295

2009

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Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450

The Journal of biological chemistry, 2001-10, Vol.276 (42), p.39411-39418

2001

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P-Glycoprotein: A Major Determinant of Rifampicin-Inducible Expression of Cytochrome P4503A in Mice and Humans

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (9), p.4001-4005

1996

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Molecular genetics of coat colour variations in White Galloway and White Park cattle

Animal genetics, 2013-08, Vol.44 (4), p.450-453

2013

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The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

Nature medicine, 2003-02, Vol.9 (2), p.220-224

2003

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Variability in human cytochrome P450 paclitaxel metabolism

The Journal of pharmacology and experimental therapeutics, 1995-11, Vol.275 (2), p.566

1995

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Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia

The Lancet (British edition), 2000-07, Vol.356 (9226), p.285-290

2000

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The Xenobiotic Compound 1,4-Bis[2-(3,5-Dichloropyridyloxy)]Benzene Is an Agonist Ligand for the Nuclear Receptor CAR

Molecular and Cellular Biology, 2000-05, Vol.20 (9), p.2951-2958

2000

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Genomic Instability in Larynx Cancer

International journal of radiation oncology, biology, physics, 2016-03, Vol.94 (4), p.938-938

2016

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Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes

Drug metabolism and disposition, 1995-03, Vol.23 (3), p.415

1995

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O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4

Molecular pharmacology, 1994-02, Vol.45 (2), p.352-358

1994

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Environmental Xenobiotics and the Antihormones Cyproterone Acetate and Spironolactone Use the Nuclear Hormone Pregnenolone X Receptor to Activate the CYP3A23 Hormone Response Element

Molecular pharmacology, 1998-12, Vol.54 (6), p.1113-1117

1998

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Pharmacogenetic Pathway Analysis of Docetaxel Elimination

Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content

Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism

Influence of Solute Carriers on the Pharmacokinetics of CYP3A4 Probes

Statistical Orbit Determination

6′,7′-Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein

Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics

PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators

Identification of functionally variant MDR1 alleles among European Americans and African Americans

Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells

Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines

Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms

Fetal MR lung volumetry in congenital diaphragmatic hernia (CDH): prediction of clinical outcome and the need for extracorporeal membrane oxygenation (ECMO)

Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450

P-Glycoprotein: A Major Determinant of Rifampicin-Inducible Expression of Cytochrome P4503A in Mice and Humans

Molecular genetics of coat colour variations in White Galloway and White Park cattle

The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

Variability in human cytochrome P450 paclitaxel metabolism

Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia

The Xenobiotic Compound 1,4-Bis[2-(3,5-Dichloropyridyloxy)]Benzene Is an Agonist Ligand for the Nuclear Receptor CAR

Genomic Instability in Larynx Cancer

Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes

O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4

Environmental Xenobiotics and the Antihormones Cyproterone Acetate and Spironolactone Use the Nuclear Hormone Pregnenolone X Receptor to Activate the CYP3A23 Hormone Response Element

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