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NRF2 Activation in Cancer: From DNA to Protein

Cancer research (Chicago, Ill.), 2019-03, Vol.79 (5), p.889-898

2019

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ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas

PloS one, 2024-02, Vol.19 (2), p.e0297741-e0297741

2024

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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

Cell reports (Cambridge), 2021-07, Vol.36 (2), p.109364-109364, Article 109364

2021

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Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (40), p.16984-16989

2009

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De-Escalated Therapy and Early Treatment of Recurrences in HPV-Associated Head and Neck Cancer: The Potential for Biomarkers to Revolutionize Personalized Therapy

Viruses, 2024-04, Vol.16 (4), p.536

2024

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Molecular characterization of the salivary adenoid cystic carcinoma immune landscape by anatomic subsites

Scientific reports, 2024-07, Vol.14 (1), p.15821-13, Article 15821

2024

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Direct Comparison of HPV16 Viral Genomic Integration, Copy Loss, and Structural Variants in Oropharyngeal and Uterine Cervical Cancers Reveal Distinct Relationships to E2 Disruption and Somatic Alteration

Cancers, 2022-09, Vol.14 (18), p.4488

2022

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Phosphorylation Increases Persistence Length and End-to-End Distance of a Segment of Tau Protein

Biophysical journal, 2016-01, Vol.110 (2), p.362-371

2016

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Case-matching analysis of head and neck squamous cell carcinoma in racial and ethnic minorities in the United States-Possible role for human papillomavirus in survival disparities

Head & neck, 2011-01, Vol.33 (1), p.45-53

2011

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The addition of chemotherapy to adjuvant radiation is associated with inferior survival outcomes in intermediate‐risk HPV‐negative HNSCC

Cancer medicine (Malden, MA), 2021-05, Vol.10 (10), p.3231-3239

2021

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Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma

Laryngoscope investigative otolaryngology, 2021-08, Vol.6 (4), p.699-707

2021

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Time to treatment patterns of head and neck cancer patients before and during the Covid-19 pandemic

Oral oncology, 2023-11, Vol.146, p.106535, Article 106535

2023

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Time to treatment for head and neck cancer patients decreased during the early phase of the Covid-19 pandemic

Oral oncology, 2024-08, Vol.155, p.106879, Article 106879

2024

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Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (32), p.e2216532120

2023

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Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC

Molecular & cellular proteomics, 2023-11, Vol.22 (11), p.100647, Article 100647

2023

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Genomic heterogeneity and copy number variant burden are associated with poor recurrence‐free survival and 11q loss in human papillomavirus‐positive squamous cell carcinoma of the oropharynx

Cancer, 2021-08, Vol.127 (15), p.2788-2800

2021

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Development of a Novel Molecular Test for Determining HPV Integration Status in HPV-Positive Oropharynx Cancers

JAMA otolaryngology-- head & neck surgery, 2022-10, Vol.148 (10), p.987

2022

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Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx

Molecular cancer research, 2022-10, Vol.20 (10), p.1489-1501

2022

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The role of protein conformational fluctuations in allostery, function, and evolution

Biophysical chemistry, 2011-11, Vol.159 (1), p.129-141

2011

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Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor

Journal of cell science, 2020-07, Vol.133 (14)

2020

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NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer

Oncotarget, 2022, Vol.13 (1), p.707-722

2022

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A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue

The Journal of pathology, 2020-10, Vol.252 (2), p.125-137

2020

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Thirty‐day readmission in patients undergoing head and neck microvascular reconstruction

Head & neck, 2018-07, Vol.40 (7), p.1366-1374

2018

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Predictors of outcomes in large cell undifferentiated carcinoma of the major salivary glands

The Laryngoscope, 2017-02, Vol.127 (2), p.372-376

2017

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Ketorolac and Hematoma Incidence in Postmastectomy Implant-Based Breast Reconstruction

Annals of plastic surgery, 2018-05, Vol.80 (5), p.472-474

2018

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NRF2 Activation in Cancer: From DNA to Protein

ARID1A loss is associated with increased NRF2 signaling in human head and neck squamous cell carcinomas

Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins

De-Escalated Therapy and Early Treatment of Recurrences in HPV-Associated Head and Neck Cancer: The Potential for Biomarkers to Revolutionize Personalized Therapy

Molecular characterization of the salivary adenoid cystic carcinoma immune landscape by anatomic subsites

Direct Comparison of HPV16 Viral Genomic Integration, Copy Loss, and Structural Variants in Oropharyngeal and Uterine Cervical Cancers Reveal Distinct Relationships to E2 Disruption and Somatic Alteration

Phosphorylation Increases Persistence Length and End-to-End Distance of a Segment of Tau Protein

Case-matching analysis of head and neck squamous cell carcinoma in racial and ethnic minorities in the United States-Possible role for human papillomavirus in survival disparities

The addition of chemotherapy to adjuvant radiation is associated with inferior survival outcomes in intermediate‐risk HPV‐negative HNSCC

Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma

Time to treatment patterns of head and neck cancer patients before and during the Covid-19 pandemic

Time to treatment for head and neck cancer patients decreased during the early phase of the Covid-19 pandemic

Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors

Targeted Proteomic Quantitation of NRF2 Signaling and Predictive Biomarkers in HNSCC

Genomic heterogeneity and copy number variant burden are associated with poor recurrence‐free survival and 11q loss in human papillomavirus‐positive squamous cell carcinoma of the oropharynx

Development of a Novel Molecular Test for Determining HPV Integration Status in HPV-Positive Oropharynx Cancers

Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx

The role of protein conformational fluctuations in allostery, function, and evolution

Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor

NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer

A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue

Thirty‐day readmission in patients undergoing head and neck microvascular reconstruction

Predictors of outcomes in large cell undifferentiated carcinoma of the major salivary glands

Ketorolac and Hematoma Incidence in Postmastectomy Implant-Based Breast Reconstruction

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