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Chemistry of Gene Silencing: The Mechanism of NAD+-Dependent Deacetylation Reactions

Biochemistry (Easton), 2001-12, Vol.40 (51), p.15456-15463

2001

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Transition State Structure of Purine Nucleoside Phosphorylase and Principles of Atomic Motion in Enzymatic Catalysis

Biochemistry (Easton), 2001-01, Vol.40 (4), p.853-860

2001

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Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine: Convergent Synthesis of the Aza-C-nucleoside Immucillins

Journal of organic chemistry, 2001-08, Vol.66 (17), p.5723-5730

2001

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Transition State Analysis for Human and Plasmodium falciparum Purine Nucleoside Phosphorylases

Biochemistry (Easton), 2004-02, Vol.43 (6), p.1458-1468

2004

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Management of Nasopharyngeal Salivary Gland Malignancy

The Laryngoscope, 2001-09, Vol.111 (9), p.1533-1544

2001

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Purine nucleoside phosphorylase. Catalytic mechanism and transition-state analysis of the arsenolysis reaction

Biochemistry (Easton), 1993-12, Vol.32 (48), p.13212-13219

1993

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Chemical Activation of Sir2-Dependent Silencing by Relief of Nicotinamide Inhibition

Molecular cell, 2005-02, Vol.17 (4), p.595-601

2005

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ENZYMATIC TRANSITION STATES AND TRANSITION STATE ANALOG DESIGN

Annual review of biochemistry, 1998-01, Vol.67 (1), p.693-720

Schramm, Vern L

1998

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Subtemporal-preauricular infratemporal fossa approach to large lateral and posterior cranial base neoplasms

Journal of neurosurgery, 1987-10, Vol.67 (4), p.488

1987

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Purine Nucleoside Phosphorylase from Mycobacterium tuberculosis. Analysis of Inhibition by a Transition-State Analogue and Dissection by Parts

Biochemistry (Easton), 2001-07, Vol.40 (28), p.8196-8203

2001

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Structures of Purine Nucleoside Phosphorylase from Mycobacterium tuberculosis in Complexes with Immucillin-H and Its Pieces

Biochemistry (Easton), 2001-07, Vol.40 (28), p.8204-8215

2001

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Structural Analysis of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae

Biochemistry (Easton), 2001-09, Vol.40 (36), p.10800-10809

2001

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A Transition-State Analogue Reduces Protein Dynamics in Hypoxanthine-Guanine Phosphoribosyltransferase

Biochemistry (Easton), 2001-07, Vol.40 (27), p.8043-8054

2001

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Promoting Vibrations in Human Purine Nucleoside Phosphorylase. A Molecular Dynamics and Hybrid Quantum Mechanical/Molecular Mechanical Study

Journal of the American Chemical Society, 2004-12, Vol.126 (48), p.15720-15729

2004

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Immucillin-H binding to purine nucleoside phosphorylase reduces dynamic solvent exchange

Protein science, 2000-09, Vol.9 (9), p.1660-1668

2000

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Achieving the Ultimate Physiological Goal in Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase

The Journal of biological chemistry, 2003-08, Vol.278 (34), p.31465-31468

2003

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Nucleoside hydrolase from Crithidia fasciculata. Metabolic role, purification, specificity, and kinetic mechanism

The Journal of biological chemistry, 1991-11, Vol.266 (31), p.20658-20665

1991

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Transition state analogue inhibitors of protozoan nucleoside hydrolases

Bioorganic & medicinal chemistry, 1999-11, Vol.7 (11), p.2599-2606

1999

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Immucillin H, A Powerful Transition-State Analog Inhibitor of Purine Nucleoside Phosphorylase, Selectively Inhibits Human T Lymphocytes

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (8), p.4593-4598

2001

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Conformational equilibrium isotope effects in glucose by (13)C NMR spectroscopy and computational studies

Journal of the American Chemical Society, 2001-02, Vol.123 (7), p.1327-1336

2001

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Transition-state analysis of nucleoside hydrolase from Crithidia fasciculata

Biochemistry (Easton), 1991-11, Vol.30 (44), p.10788-10795

1991

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Ricin A-Chain Inhibitors Resembling the Oxacarbenium Ion Transition State

Biochemistry (Easton), 2001-06, Vol.40 (23), p.6845-6851

2001

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Electronic nature of the transition state for nucleoside hydrolase. A blueprint for inhibitor design

Biochemistry (Easton), 1993-07, Vol.32 (28), p.7089-7097

1993

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Transition state analysis and inhibitor design for enzymatic reactions

The Journal of biological chemistry, 1994-07, Vol.269 (28), p.18259-18262

1994

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Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase

The Journal of biological chemistry, 2002-02, Vol.277 (5), p.3226-3231

2002

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Chemistry of Gene Silencing: The Mechanism of NAD+-Dependent Deacetylation Reactions

Transition State Structure of Purine Nucleoside Phosphorylase and Principles of Atomic Motion in Enzymatic Catalysis

Addition of Lithiated 9-Deazapurine Derivatives to a Carbohydrate Cyclic Imine: Convergent Synthesis of the Aza-C-nucleoside Immucillins

Transition State Analysis for Human and Plasmodium falciparum Purine Nucleoside Phosphorylases

Management of Nasopharyngeal Salivary Gland Malignancy

Purine nucleoside phosphorylase. Catalytic mechanism and transition-state analysis of the arsenolysis reaction

Chemical Activation of Sir2-Dependent Silencing by Relief of Nicotinamide Inhibition

ENZYMATIC TRANSITION STATES AND TRANSITION STATE ANALOG DESIGN

Subtemporal-preauricular infratemporal fossa approach to large lateral and posterior cranial base neoplasms

Purine Nucleoside Phosphorylase from Mycobacterium tuberculosis. Analysis of Inhibition by a Transition-State Analogue and Dissection by Parts

Structures of Purine Nucleoside Phosphorylase from Mycobacterium tuberculosis in Complexes with Immucillin-H and Its Pieces

Structural Analysis of Adenine Phosphoribosyltransferase from Saccharomyces cerevisiae

A Transition-State Analogue Reduces Protein Dynamics in Hypoxanthine-Guanine Phosphoribosyltransferase

Promoting Vibrations in Human Purine Nucleoside Phosphorylase. A Molecular Dynamics and Hybrid Quantum Mechanical/Molecular Mechanical Study

Immucillin-H binding to purine nucleoside phosphorylase reduces dynamic solvent exchange

Achieving the Ultimate Physiological Goal in Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase

Nucleoside hydrolase from Crithidia fasciculata. Metabolic role, purification, specificity, and kinetic mechanism

Transition state analogue inhibitors of protozoan nucleoside hydrolases

Immucillin H, A Powerful Transition-State Analog Inhibitor of Purine Nucleoside Phosphorylase, Selectively Inhibits Human T Lymphocytes

Conformational equilibrium isotope effects in glucose by (13)C NMR spectroscopy and computational studies

Transition-state analysis of nucleoside hydrolase from Crithidia fasciculata

Ricin A-Chain Inhibitors Resembling the Oxacarbenium Ion Transition State

Electronic nature of the transition state for nucleoside hydrolase. A blueprint for inhibitor design

Transition state analysis and inhibitor design for enzymatic reactions

Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase

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