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Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.705-713

2016

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Hydrogen bonds and proton transfer in general-catalytic transition-state stabilization in enzyme catalysis

BBA - Bioenergetics, 2000-05, Vol.1458 (1), p.43-62

2000

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Isotope effects and temperature dependences in the action of the glucose dehydrogenase of the mesophilic bacterium Bacillus megaterium

Journal of physical organic chemistry, 2013-12, Vol.26 (12), p.1066-1070

2013

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Polyvinylpyrrolidone–drug conjugate: synthesis and release mechanism

Journal of controlled release, 2004-01, Vol.94 (1), p.91-100

2004

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Heavy atom motions and tunneling in hydrogen transfer reactions: the importance of the pre-tunneling state

Journal of physical organic chemistry, 2010-07, Vol.23 (7), p.586-605

2010

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Report

Screen bodies (Print), 2017-01, Vol.2 (1)

Schowen, Ryan

2017

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A Tribute to Ronald T. Borchardt—Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.370-385

2016

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Secondary Structure and Protein Deamidation

Journal of pharmaceutical sciences, 1999-01, Vol.88 (1), p.8-13

1999

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The Photo-Favorskii Reaction of p-Hydroxyphenacyl Compounds Is Initiated by Water-Assisted, Adiabatic Extrusion of a Triplet Biradical

Journal of the American Chemical Society, 2008-03, Vol.130 (11), p.3307-3309

2008

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The Crystal Structures of Klebsiella pneumoniae Acetolactate Synthase with Enzyme-bound Cofactor and with an Unusual Intermediate

The Journal of biological chemistry, 2004-01, Vol.279 (3), p.2242-2253

2004

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A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells

Pharmaceutical research, 2001-02, Vol.18 (2), p.171-176

2001

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How an Enzyme Surmounts the Activation Energy Barrier

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.11931-11932

Schowen, Richard L.

2003

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The Trapping of a Spontaneously “Flipped-Out” Base from Double Helical Nucleic Acids by Host−Guest Complexation with β-Cyclodextrin: The Intrinsic Base-Flipping Rate Constant for DNA and RNA

Journal of the American Chemical Society, 2002-11, Vol.124 (47), p.14049-14053

2002

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Effect of ‘pH’ on the rate of asparagine deamidation in polymeric formulations: ‘pH’–rate profile

Journal of pharmaceutical sciences, 2001-02, Vol.90 (2), p.141-156

2001

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Catalytic Strategy of S-Adenosyl-l-homocysteine Hydrolase: Transition-State Stabilization and the Avoidance of Abortive Reactions

Biochemistry (Easton), 2003-02, Vol.42 (7), p.1900-1909

2003

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Characterizing protein structure in amorphous solids using hydrogen/deuterium exchange with mass spectrometry

Analytical biochemistry, 2007-07, Vol.366 (1), p.18-28

2007

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Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide: Pharmaceutics, Drug Delivery and Pharmaceutical Technology

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.705-713

2016

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The antiviral drug ribavirin is a selective inhibitor of S-adenosyl- l-homocysteine hydrolase from Trypanosoma cruzi

Bioorganic & medicinal chemistry, 2007-12, Vol.15 (23), p.7281-7287

2007

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Racemization of an Asparagine Residue during Peptide Deamidation

Journal of the American Chemical Society, 2003-09, Vol.125 (38), p.11486-11487

2003

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The use of solvent isotope effects in the pursuit of enzyme mechanisms

Journal of labelled compounds & radiopharmaceuticals, 2007-10, Vol.50 (11-12), p.1052-1062

Schowen, Richard L.

2007

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The linkage of catalysis and regulation in enzyme action: oxidative diversion in the hysteretically regulated yeast pyruvate decarboxylase

Bioorganic & medicinal chemistry, 1999-05, Vol.7 (5), p.887-894

1999

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Chemical stability of peptides in polymers. 2. Discriminating between solvent and plasticizing effects of water on peptide deamidation in poly(vinylpyrrolidone)

Journal of pharmaceutical sciences, 1999-10, Vol.88 (10), p.1081-1089

1999

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Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 1. Basic Features of the Association and Dissociation Processes

Biochemistry (Easton), 2007-05, Vol.46 (19), p.5798-5809

2007

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Chemical stability of peptides in polymers. 1. Effect of water on peptide deamidation in poly(vinyl alcohol) and poly(vinyl pyrrolidone) matrixes

Journal of pharmaceutical sciences, 1999-10, Vol.88 (10), p.1073-1080

1999

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Molecular dynamics simulations of domain motions of substrate-free S-adenosyl- L-homocysteine hydrolase in solution

Proteins, structure, function, and bioinformatics, 2008-04, Vol.71 (1), p.131-143

2008

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Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide

Hydrogen bonds and proton transfer in general-catalytic transition-state stabilization in enzyme catalysis

Isotope effects and temperature dependences in the action of the glucose dehydrogenase of the mesophilic bacterium Bacillus megaterium

Polyvinylpyrrolidone–drug conjugate: synthesis and release mechanism

Heavy atom motions and tunneling in hydrogen transfer reactions: the importance of the pre-tunneling state

Report

A Tribute to Ronald T. Borchardt—Teacher, Mentor, Scientist, Colleague, Leader, Friend, and Family Man

Secondary Structure and Protein Deamidation

The Photo-Favorskii Reaction of p-Hydroxyphenacyl Compounds Is Initiated by Water-Assisted, Adiabatic Extrusion of a Triplet Biradical

The Crystal Structures of Klebsiella pneumoniae Acetolactate Synthase with Enzyme-bound Cofactor and with an Unusual Intermediate

A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells

How an Enzyme Surmounts the Activation Energy Barrier

The Trapping of a Spontaneously “Flipped-Out” Base from Double Helical Nucleic Acids by Host−Guest Complexation with β-Cyclodextrin: The Intrinsic Base-Flipping Rate Constant for DNA and RNA

Effect of ‘pH’ on the rate of asparagine deamidation in polymeric formulations: ‘pH’–rate profile

Catalytic Strategy of S-Adenosyl-l-homocysteine Hydrolase: Transition-State Stabilization and the Avoidance of Abortive Reactions

Characterizing protein structure in amorphous solids using hydrogen/deuterium exchange with mass spectrometry

Mechanism of Decarboxylation of Pyruvic Acid in the Presence of Hydrogen Peroxide: Pharmaceutics, Drug Delivery and Pharmaceutical Technology

The antiviral drug ribavirin is a selective inhibitor of S-adenosyl- l-homocysteine hydrolase from Trypanosoma cruzi

Racemization of an Asparagine Residue during Peptide Deamidation

The use of solvent isotope effects in the pursuit of enzyme mechanisms

The linkage of catalysis and regulation in enzyme action: oxidative diversion in the hysteretically regulated yeast pyruvate decarboxylase

Chemical stability of peptides in polymers. 2. Discriminating between solvent and plasticizing effects of water on peptide deamidation in poly(vinylpyrrolidone)

Comparative Kinetics of Cofactor Association and Dissociation for the Human and Trypanosomal S-Adenosylhomocysteine Hydrolases. 1. Basic Features of the Association and Dissociation Processes

Chemical stability of peptides in polymers. 1. Effect of water on peptide deamidation in poly(vinyl alcohol) and poly(vinyl pyrrolidone) matrixes

Molecular dynamics simulations of domain motions of substrate-free S-adenosyl- L-homocysteine hydrolase in solution

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