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erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships

Journal of medicinal chemistry, 1995-09, Vol.38 (19), p.3813-3820

1995

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Binding of Benzoquinoid Ansamycins to p100 Correlates with Their Ability to Deplete the erbB2 Gene Product p185

Biochemical and biophysical research communications, 1994-06, Vol.201 (3), p.1313-1319

1994

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Spiro Hydantoin Aldose Reductase Inhibitors

Journal of medicinal chemistry, 1988-01, Vol.31 (1), p.230-243

1988

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Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives

Journal of medicinal chemistry, 1995-09, Vol.38 (19), p.3806-3812

1995

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In Vitro Microbiological Characterization of Novel Cyclic Homopentapeptides, CP-101, 680 and CP-163, 234, for Animal Health Use

The Journal of Antibiotics, 1999/11/25, Vol.52(11), pp.1007-1016

1999

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erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships

Journal of medicinal chemistry, 1995-09, Vol.38 (19), p.3813-3820

1995

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N-(5-fluorobenzothiazol-2-yl)-2-guanidinothiazole-4-carboxamide. A novel, systemically active antitumor agent effective against 3LL Lewis Lung carcinoma

Journal of medicinal chemistry, 1991-03, Vol.34 (3), p.914-918

1991

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Tandem [3,3]-Sigmatropic Rearrangements in an Ansamycin: Stereospecific Conversion of an (S)-Allylic Alcohol to an (S)-Allylic Amine Derivative

Journal of organic chemistry, 1994-05, Vol.59 (9), p.2581-2584

1994

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Quantitative structure-activity relationships of antitumor guanidinothiazolecarboxamides with survival enhancement for therapy in the 3LL Lewis lung carcinoma model

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.1975-1982

1991

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Improved glucose tolerance in rats treated with oxazolidinediones

Journal of medicinal chemistry, 1986-05, Vol.29 (5), p.770-778

1986

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Rotationally restricted mimics of rigid molecules: nonspirocyclic hydantoin aldose reductase inhibitors

Journal of medicinal chemistry, 1989-06, Vol.32 (6), p.1208-1213

1989

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Depletion of p185erbB2, Raf-1 and mutant p53 proteins by geldanamycin derivatives correlates with antiproliferative activity

Cancer chemotherapy and pharmacology, 1997, Vol.40 (1), p.60-64

1997

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Depletion of the erbB-2 gene product p185 by benzoquinoid ansamycins

Cancer research (Chicago, Ill.), 1994-05, Vol.54 (10), p.2724-2730

1994

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Dehydrations with N-methyl-N,N'-di-tert-butylcarbodiimidium ion

Journal of the American Chemical Society, 1975-01, Vol.97 (2), p.464-465

1975

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Synthesis of novel 1,3-oxazino[6,5-b]indole-2,4-(3H,9H)-dione and 2H-1,3,5-oxadiazino[3,2-a]indole-2,4-(3H)-dione from oxindoles

Journal of heterocyclic chemistry, 1992-03, Vol.29 (2), p.369-373

1992

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Synthesis of novel 1H-imidazo[5,1-B][3]benzazepine-1,3(2H)-dione and pyrimido[6,1-B][3]benzazepine-1,3,4(2H)-trione

Journal of heterocyclic chemistry, 1990-05, Vol.27 (4), p.963-966

1990

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Spiro oxazolidinedione aldose reductase inhibitors

Journal of medicinal chemistry, 1982-12, Vol.25 (12), p.1451-1454

1982

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Preparation of 17-amino-22-(4'-azido-3'- super(125)iodophenacyl)-17-demethoxygeldanamycin (1): An ansamycin for photoaffinity labeling

Journal of labelled compounds & radiopharmaceuticals, 1994-01, Vol.34 (6), p.529-536

1994

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Preparation of 17-amino-22-(4'-azido-3'-125iodophenacyl)-17-demethoxygeldanamycin. I: An ansamycin for photoaffinity labeling

Journal of labelled compounds & radiopharmaceuticals, 1994, Vol.34 (6), p.529-535

1994

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Synthesis of 1,2-dihydro-1-oxo-3H-3benzazepine and 3-acyl derivatives

Journal of organic chemistry, 1989, Vol.54 (1), p.216-220

1989

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Inhibition of the oncogene product p185 super(erbB-2) in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives

Journal of medicinal chemistry, 1995-01, Vol.38 (19), p.3806-3812

1995

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Quantitative structure-activity relationships of antitumor guanidinothiazole-carboxamides with survival enhancement for therapy in the 3LL Lewis lung carcinoma model

Journal of medicinal chemistry, 1991-01, Vol.34 (7), p.1975-1982

1991

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ChemInform Abstract: CAUTION WITH PERESTER

Chemischer Informationsdienst, 1981-09, Vol.12 (38)

SCHNUR, R. C.

1981

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ChemInform Abstract: A GENERALIZED AND PROTON‐CATALYZED SYNTHESIS OF AMIDINES FROM THIOIMIDATES

Chemischer Informationsdienst, 1980-02, Vol.11 (7)

SCHNUR, R. C.

1980

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Synthesis of 1,2-dihydro-1-oxo-3H-3-benzazepine and 3-acyl derivatives

Journal of organic chemistry, 1989-01, Vol.54 (1), p.216-220

1989

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erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships

Binding of Benzoquinoid Ansamycins to p100 Correlates with Their Ability to Deplete the erbB2 Gene Product p185

Spiro Hydantoin Aldose Reductase Inhibitors

Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives

In Vitro Microbiological Characterization of Novel Cyclic Homopentapeptides, CP-101, 680 and CP-163, 234, for Animal Health Use

erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships

N-(5-fluorobenzothiazol-2-yl)-2-guanidinothiazole-4-carboxamide. A novel, systemically active antitumor agent effective against 3LL Lewis Lung carcinoma

Tandem [3,3]-Sigmatropic Rearrangements in an Ansamycin: Stereospecific Conversion of an (S)-Allylic Alcohol to an (S)-Allylic Amine Derivative

Quantitative structure-activity relationships of antitumor guanidinothiazolecarboxamides with survival enhancement for therapy in the 3LL Lewis lung carcinoma model

Improved glucose tolerance in rats treated with oxazolidinediones

Rotationally restricted mimics of rigid molecules: nonspirocyclic hydantoin aldose reductase inhibitors

Depletion of p185erbB2, Raf-1 and mutant p53 proteins by geldanamycin derivatives correlates with antiproliferative activity

Depletion of the erbB-2 gene product p185 by benzoquinoid ansamycins

Dehydrations with N-methyl-N,N'-di-tert-butylcarbodiimidium ion

Synthesis of novel 1,3-oxazino[6,5-b]indole-2,4-(3H,9H)-dione and 2H-1,3,5-oxadiazino[3,2-a]indole-2,4-(3H)-dione from oxindoles

Synthesis of novel 1H-imidazo[5,1-B][3]benzazepine-1,3(2H)-dione and pyrimido[6,1-B][3]benzazepine-1,3,4(2H)-trione

Spiro oxazolidinedione aldose reductase inhibitors

Preparation of 17-amino-22-(4'-azido-3'- super(125)iodophenacyl)-17-demethoxygeldanamycin (1): An ansamycin for photoaffinity labeling

Preparation of 17-amino-22-(4'-azido-3'-125iodophenacyl)-17-demethoxygeldanamycin. I: An ansamycin for photoaffinity labeling

Synthesis of 1,2-dihydro-1-oxo-3H-3benzazepine and 3-acyl derivatives

Inhibition of the oncogene product p185 super(erbB-2) in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives

Quantitative structure-activity relationships of antitumor guanidinothiazole-carboxamides with survival enhancement for therapy in the 3LL Lewis lung carcinoma model

ChemInform Abstract: CAUTION WITH PERESTER

ChemInform Abstract: A GENERALIZED AND PROTON‐CATALYZED SYNTHESIS OF AMIDINES FROM THIOIMIDATES

Synthesis of 1,2-dihydro-1-oxo-3H-3-benzazepine and 3-acyl derivatives

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