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Benzofuro[3,2-b]pyridines as mixed ETA/ETB and selective ETB endothelin receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (4), p.619-622

1999

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Renin inhibitors containing new P1-P1' dipeptide mimetics with heterocycles in P1'

Journal of medicinal chemistry, 1992-09, Vol.35 (19), p.3525-3536

1992

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Modulation of Cyclic AMP Metabolism by S-adenosylhomocysteine and S-3-deazaadenosylhomocysteine in Mouse Lymphocytes

Proceedings of the National Academy of Sciences - PNAS, 1980-10, Vol.77 (10), p.5639-5643

1980

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Cyclic adenosine 3′,5′-monophosphate and prostacyclin inhibit membrane phospholipase activity in platelets

Biochemical and biophysical research communications, 1977-06, Vol.76 (3), p.828-835

1977

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2. Endothelin antagonists : Evaluation of 2,1,3-benzothiadiazole as a methylendioxyphenyl bioisoster

Bioorganic & medicinal chemistry letters, 1998-01, Vol.8 (1), p.17-22

1998

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Specific Phospholipids are Required to Reconstitute Adenylate Cyclase Solubilized from Rat Brain

Proceedings of the National Academy of Sciences - PNAS, 1981-01, Vol.78 (1), p.120-123

1981

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High β1-Selectivity and Favourable Pharmacokinetics as the Outstanding Properties of Bisoprolol

Journal of cardiovascular pharmacology, 1985-11, Vol.8 Suppl 11, p.S2-S15

1985

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Action of Corticosteroids in Regulation of Prostaglandin Biosynthesis in Cultured Fibroblasts

Proceedings of the National Academy of Sciences - PNAS, 1978-01, Vol.75 (1), p.214-217

1978

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3. endothelin antagonists : Discovery of EMD 122946, a highly potent and orally active ETA selective antagonist

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (13), p.1771-1776

1998

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Pyridazinones with a pendant acylsulfonamide moiety as endothelin receptor antagonists

Bioorganic & medicinal chemistry letters, 1997-02, Vol.7 (3), p.275-280

1997

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Incorporation of rat brain adenylate cyclase into artificial phospholipid vesicles

The Journal of biological chemistry, 1979-10, Vol.254 (20), p.10459-10465

1979

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Substrate analog renin inhibitors containing replacements of histidine in P2 or isosteres of the amide bond between P3 and P2 sites

Journal of medicinal chemistry, 1991-11, Vol.34 (11), p.3267-3280

1991

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Properties of the Interaction of Fluoride- and guanylyl-5′-imidodiphosphate-Regulatory Proteins with Adenylate Cyclase

Proceedings of the National Academy of Sciences - PNAS, 1978-08, Vol.75 (8), p.3693-3697

1978

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Studies on the receptor profile of bisoprolol

Arzneimittel-Forschung, 1986-02, Vol.36 (2), p.197

1986

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Inhibition of Lymphocyte-Mediated Cytolysis and Cyclic amp Phosphodiesterase by Erythro-9-(2-Hydroxy-3-Nonyl)Adenine

Immunopharmacology and immunotoxicology, 1982, Vol.4 (1-2), p.79-100

1982

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Benzofuro[3,2-b]pyridines as mixed ET(A)/ET(B) and selective ET(B) endothelin receptor antagonists

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (4), p.619-622

1999

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1,4-Diaryl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acids as endothelin receptor antagonists

Bioorganic & medicinal chemistry letters, 1997-07, Vol.7 (14), p.1883-1886

1997

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The Major Proteins of the Escherichia coli Outer Cell‐Envelope Membrane. Heterogeneity of Protein I

European journal of biochemistry, 1976-03, Vol.63 (1), p.47-52

1976

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High beta 1-selectivity and favourable pharmacokinetics as the outstanding properties of bisoprolol

Journal of cardiovascular pharmacology, 1986, Vol.8 Suppl 11, p.S2-15

1986

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Non-peptide Renin Inhibitors Containing 2-(((3-Phenylpropyl)phosphoryl)oxy)alkanoic Acid Moieties as P2-P3 Replacements

Journal of medicinal chemistry, 1994-02, Vol.37 (4), p.486-497

1994

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ChemInform Abstract: 1,4-Diaryl-2-oxo-1,2-dihydro-quinoline-3-carboxylic Acids as Endothelin Receptor Antagonists

ChemInform, 1997-12, Vol.28 (49), p.no-no

1997

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ChemInform Abstract: Non-Peptide Renin Inhibitors Containing 2-(((3-Phenylpropyl)phosphoryl) oxy)alkanoic Acid Moieties as P2-P3 Replacements

ChemInform, 1994-06, Vol.25 (25), p.no-no

1994

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ChemInform Abstract: HIV Protease Inhibitors. A Promising New Class of AIDS Therapeutics

ChemInform, 1994-02, Vol.25 (7), p.no-no

1994

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ChemInform Abstract: Endothelin Antagonists. Part 3. Discovery of EMD 122946, a Highly Potent and Orally Active ETA Selective Antagonist

ChemInform, 1998-11, Vol.29 (44), p.no-no

1998

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ChemInform Abstract: Endothelin Antagonists. Part 2. Evaluation of 2,1,3-Benzothiadiazole as a Methylendioxyphenyl Bioisoster

ChemInform, 1998-05, Vol.29 (18), p.no-no

1998

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Benzofuro[3,2-b]pyridines as mixed ETA/ETB and selective ETB endothelin receptor antagonists

Renin inhibitors containing new P1-P1' dipeptide mimetics with heterocycles in P1'

Modulation of Cyclic AMP Metabolism by S-adenosylhomocysteine and S-3-deazaadenosylhomocysteine in Mouse Lymphocytes

Cyclic adenosine 3′,5′-monophosphate and prostacyclin inhibit membrane phospholipase activity in platelets

2. Endothelin antagonists : Evaluation of 2,1,3-benzothiadiazole as a methylendioxyphenyl bioisoster

Specific Phospholipids are Required to Reconstitute Adenylate Cyclase Solubilized from Rat Brain

High β1-Selectivity and Favourable Pharmacokinetics as the Outstanding Properties of Bisoprolol

Action of Corticosteroids in Regulation of Prostaglandin Biosynthesis in Cultured Fibroblasts

3. endothelin antagonists : Discovery of EMD 122946, a highly potent and orally active ETA selective antagonist

Pyridazinones with a pendant acylsulfonamide moiety as endothelin receptor antagonists

Incorporation of rat brain adenylate cyclase into artificial phospholipid vesicles

Substrate analog renin inhibitors containing replacements of histidine in P2 or isosteres of the amide bond between P3 and P2 sites

Properties of the Interaction of Fluoride- and guanylyl-5′-imidodiphosphate-Regulatory Proteins with Adenylate Cyclase

Studies on the receptor profile of bisoprolol

Inhibition of Lymphocyte-Mediated Cytolysis and Cyclic amp Phosphodiesterase by Erythro-9-(2-Hydroxy-3-Nonyl)Adenine

Benzofuro[3,2-b]pyridines as mixed ET(A)/ET(B) and selective ET(B) endothelin receptor antagonists

1,4-Diaryl-2-oxo-1,2-dihydro-quinoline-3-carboxylic acids as endothelin receptor antagonists

The Major Proteins of the Escherichia coli Outer Cell‐Envelope Membrane. Heterogeneity of Protein I

High beta 1-selectivity and favourable pharmacokinetics as the outstanding properties of bisoprolol

Non-peptide Renin Inhibitors Containing 2-(((3-Phenylpropyl)phosphoryl)oxy)alkanoic Acid Moieties as P2-P3 Replacements

ChemInform Abstract: 1,4-Diaryl-2-oxo-1,2-dihydro-quinoline-3-carboxylic Acids as Endothelin Receptor Antagonists

ChemInform Abstract: Non-Peptide Renin Inhibitors Containing 2-(((3-Phenylpropyl)phosphoryl) oxy)alkanoic Acid Moieties as P2-P3 Replacements

ChemInform Abstract: HIV Protease Inhibitors. A Promising New Class of AIDS Therapeutics

ChemInform Abstract: Endothelin Antagonists. Part 3. Discovery of EMD 122946, a Highly Potent and Orally Active ETA Selective Antagonist

ChemInform Abstract: Endothelin Antagonists. Part 2. Evaluation of 2,1,3-Benzothiadiazole as a Methylendioxyphenyl Bioisoster

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