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Ubiquitin-proteasome system and hereditary cardiomyopathies

Journal of molecular and cellular cardiology, 2014-06, Vol.71, p.25-31

2014

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Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities

Journal of molecular and cellular cardiology, 2011-04, Vol.50 (4), p.613-620

2011

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Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

EMBO molecular medicine, 2019-12, Vol.11 (12), p.e11115-n/a

2019

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Mybpc3 gene therapy for neonatal cardiomyopathy enables long-term disease prevention in mice

Nature communications, 2014-12, Vol.5 (1), p.5515, Article 5515

2014

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How do MYBPC3 mutations cause hypertrophic cardiomyopathy?

Journal of muscle research and cell motility, 2012-05, Vol.33 (1), p.75-80

2012

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Nonsense-Mediated mRNA Decay and Ubiquitin–Proteasome System Regulate Cardiac Myosin-Binding Protein C Mutant Levels in Cardiomyopathic Mice

Circulation research, 2009-07, Vol.105 (3), p.239-248

2009

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Aldosterone Inhibits Antifibrotic Factors in Mouse Hypertensive Heart

Hypertension (Dallas, Tex. 1979), 2012-06, Vol.59 (6), p.1179-1187

2012

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A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway

Frontiers in physiology, 2021-04, Vol.12, p.614878-614878

2021

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DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death

Human molecular genetics, 2012-03, Vol.21 (5), p.1037-1048

2012

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Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

EMBO molecular medicine, 2022-08, Vol.14 (8), p.e16423-n/a

2022

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Cardiac Myosin-Binding Protein C Is Required for Complete Relaxation in Intact Myocytes

Circulation research, 2007-10, Vol.101 (9), p.928-938

2007

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Sacubitril/valsartan reduces proteasome activation and cardiomyocyte area in an experimental mouse model of hypertrophy

Journal of Molecular and Cellular Cardiology Plus (Online), 2024-03, Vol.7, p.100059, Article 100059

2024

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Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

Cardiovascular research, 2010-01, Vol.85 (2), p.357-366

2010

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The expression of podocyte-specific proteins in parietal epithelial cells is regulated by protein degradation

Kidney international, 2013-09, Vol.84 (3), p.532-544

2013

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ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes

Cells (Basel, Switzerland), 2022-09, Vol.11 (17), p.2745

2022

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Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice

Journal of muscle research and cell motility, 2012-05, Vol.33 (1), p.5-15

2012

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Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: A two-hit model of hypertrophic cardiomyopathy

Journal of Molecular and Cellular Cardiology Plus (Online), 2023-12, Vol.6, p.100050, Article 100050

2023

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Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice

PloS one, 2012-05, Vol.7 (5), p.e38197

2012

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The ubiquitin–proteasome system in cardiomyopathies

Current opinion in cardiology, 2011-05, Vol.26 (3), p.190-195

2011

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Impact of AT2 receptor deficiency on postnatal cardiovascular development

PloS one, 2012-10, Vol.7 (10), p.e47916-e47916

2012

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A human CRYABR120G Desmin-related cardiomyopathy cellular model

Journal of molecular and cellular cardiology, 2022-12, Vol.173, p.112-112

2022

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Autophagy in cardiomyopathies

Biochimica et biophysica acta. Molecular cell research, 2020-03, Vol.1867 (3), p.118432, Article 118432

2020

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Evaluation of the effect of LCZ696 in human iPSC-derived cardiomyocyte hypertrophy and tubulin detyrosination

Journal of molecular and cellular cardiology, 2022-12, Vol.173, p.56-57

2022

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Myoarchitectural disarray of hypertrophic cardiomyopathy begins pre‐birth

Journal of anatomy, 2019-11, Vol.235 (5), p.962-976

2019

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JAK1 Inhibitors reduce CRYABR120G aggregates in rat and human cardiomyocytes

Journal of molecular and cellular cardiology, 2022-12, Vol.173, p.95-96

2022

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Ubiquitin-proteasome system and hereditary cardiomyopathies

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: Mechanisms and therapeutic opportunities

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

Mybpc3 gene therapy for neonatal cardiomyopathy enables long-term disease prevention in mice

How do MYBPC3 mutations cause hypertrophic cardiomyopathy?

Nonsense-Mediated mRNA Decay and Ubiquitin–Proteasome System Regulate Cardiac Myosin-Binding Protein C Mutant Levels in Cardiomyopathic Mice

Aldosterone Inhibits Antifibrotic Factors in Mouse Hypertensive Heart

A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway

DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

Cardiac Myosin-Binding Protein C Is Required for Complete Relaxation in Intact Myocytes

Sacubitril/valsartan reduces proteasome activation and cardiomyocyte area in an experimental mouse model of hypertrophy

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

The expression of podocyte-specific proteins in parietal epithelial cells is regulated by protein degradation

ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes

Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice

Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: A two-hit model of hypertrophic cardiomyopathy

Aldosterone inhibits the fetal program and increases hypertrophy in the heart of hypertensive mice

The ubiquitin–proteasome system in cardiomyopathies

Impact of AT2 receptor deficiency on postnatal cardiovascular development

A human CRYABR120G Desmin-related cardiomyopathy cellular model

Autophagy in cardiomyopathies

Evaluation of the effect of LCZ696 in human iPSC-derived cardiomyocyte hypertrophy and tubulin detyrosination

Myoarchitectural disarray of hypertrophic cardiomyopathy begins pre‐birth

JAK1 Inhibitors reduce CRYABR120G aggregates in rat and human cardiomyocytes

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