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Mitochondrial matrix proteases as novel therapeutic targets in malignancy

Oncogene, 2014-05, Vol.33 (21), p.2690-2699

2014

Volltextzugriff (PDF)

Clioquinol - a novel copper-dependent and independent proteasome inhibitor

Current cancer drug targets, 2011-03, Vol.11 (3), p.325

Schimmer, A D

2011

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Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells

Leukemia, 2012-04, Vol.26 (4), p.757-768

2012

Volltextzugriff (PDF)

Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma

Leukemia, 2009-03, Vol.23 (3), p.585-590

2009

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Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity

Leukemia, 2013-06, Vol.27 (6), p.1236-1244

2013

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Targeting XIAP for the treatment of malignancy

Cell death and differentiation, 2006-02, Vol.13 (2), p.179-188

2006

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Biological and clinical consequences of NPM1 mutations in AML

Leukemia, 2017-04, Vol.31 (4), p.798-807

2017

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New model systems provide insights into Myc-induced transformation

Oncogene, 2011-08, Vol.30 (34), p.3727-3734

2011

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A phase I II study of imatinib plus reinduction therapy for c-kit-positive relapsed refractory acute myeloid leukemia: inhibition of Akt activation correlates with complete response

Leukemia, 2011-06, Vol.25 (6), p.945-952

2011

Volltextzugriff (PDF)

Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL

Leukemia, 2003-11, Vol.17 (11), p.2122-2129

2003

Volltextzugriff (PDF)

Impaired bortezomib binding to mutant beta 5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells

Leukemia, 2012-04, Vol.26 (4), p.757-768

2012

Volltextzugriff (PDF)

The repositioning of the anti-fungal agent ciclopirox olamine as a novel therapeutic agent for the treatment of haematologic malignancy

Journal of clinical pharmacy and therapeutics, 2011-04, Vol.36 (2), p.128-134

2011

Volltextzugriff (PDF)

A phase I study of tipifarnib combined with conventional induction and consolidation therapy for previously untreated patients with acute myeloid leukemia aged 60 years and over

Leukemia, 2009-04, Vol.23 (4), p.631-634

2009

Volltextzugriff (PDF)

Effect of an antimicrobial stewardship programme on antimicrobial utilisation and costs in patients with leukaemia: a retrospective controlled study

Clinical microbiology and infection, 2018-08, Vol.24 (8), p.882-888

2018

Volltextzugriff (PDF)

Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors

Haematologica (Roma), 2013-12, Vol.98 (12), p.1896-1904

2013

Volltextzugriff (PDF)

Decreased bone mineral density is common after autologous blood or marrow transplantation

Bone marrow transplantation (Basingstoke), 2001-08, Vol.28 (4), p.387-391

2001

Volltextzugriff (PDF)

Allogeneic or autologous bone marrow transplantation (BMT) for non-Hodgkin's lymphoma (NHL): results of a provincial strategy

Bone marrow transplantation (Basingstoke), 2000-10, Vol.26 (8), p.859-864

2000

Volltextzugriff (PDF)

Ovarian function after autologous bone marrow transplantation

Journal of clinical oncology, 1998-07, Vol.16 (7), p.2359-2363

1998

Volltextzugriff (PDF)

Expression of CD4 is correlated with an unfavorable prognosis in wild‐type NPM1, FLT3‐ITD‐negative cytogenetically normal adult acute myeloid leukemia

International journal of laboratory hematology, 2017-08, Vol.39 (4), p.429-437

2017

Volltextzugriff (PDF)

Venous thromboembolism prevention during asparaginase-based therapy for acute lymphoblastic leukemia

Current oncology (Toronto), 2016-08, Vol.23 (4), p.e355-361

2016

Volltextzugriff (PDF)

P500: A REAL WORLD MULTI CENTRE STUDY OF CPX‐351 REVEALS NO DIFFERENCE IN OVERALL SURVIVAL WHEN COMPARED WITH FLAG‐IDA AND 3 + 7 IN HIGH RISK AML

HemaSphere, 2022-06, Vol.6, p.399-400

2022

Volltextzugriff (PDF)

Critical Role for Fas-Associated Death Domain–Like Interleukin-1–Converting Enzyme–Like Inhibitory Protein in Anoikis Resistance and Distant Tumor Formation

JNCI : Journal of the National Cancer Institute, 2007-05, Vol.99 (10), p.811-822

2007

Volltextzugriff (PDF)

The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2

Cell death and differentiation, 2001-07, Vol.8 (7), p.725-733

2001

Volltextzugriff (PDF)

Busulfan and cyclophosphamide as a preparative regimen for allogeneic blood and marrow transplantation in patients with non-Hodgkin's lymphoma

Bone marrow transplantation (Basingstoke), 2003-01, Vol.31 (2), p.73-78

2003

Volltextzugriff (PDF)

Treatment of elderly patients with acute lymphoblastic leukemia—Evidence for a benefit of imatinib in BCR-ABL positive patients

Leukemia research, 2005-12, Vol.29 (12), p.1381-1386

2005

Volltextzugriff (PDF)

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Mitochondrial matrix proteases as novel therapeutic targets in malignancy

Clioquinol - a novel copper-dependent and independent proteasome inhibitor

Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells

Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma

Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity

Targeting XIAP for the treatment of malignancy

Biological and clinical consequences of NPM1 mutations in AML

New model systems provide insights into Myc-induced transformation

A phase I II study of imatinib plus reinduction therapy for c-kit-positive relapsed refractory acute myeloid leukemia: inhibition of Akt activation correlates with complete response

Synthetic triterpenoids activate a pathway for apoptosis in AML cells involving downregulation of FLIP and sensitization to TRAIL

Impaired bortezomib binding to mutant beta 5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells

The repositioning of the anti-fungal agent ciclopirox olamine as a novel therapeutic agent for the treatment of haematologic malignancy

A phase I study of tipifarnib combined with conventional induction and consolidation therapy for previously untreated patients with acute myeloid leukemia aged 60 years and over

Effect of an antimicrobial stewardship programme on antimicrobial utilisation and costs in patients with leukaemia: a retrospective controlled study

Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors

Decreased bone mineral density is common after autologous blood or marrow transplantation

Allogeneic or autologous bone marrow transplantation (BMT) for non-Hodgkin's lymphoma (NHL): results of a provincial strategy

Ovarian function after autologous bone marrow transplantation

Expression of CD4 is correlated with an unfavorable prognosis in wild‐type NPM1, FLT3‐ITD‐negative cytogenetically normal adult acute myeloid leukemia

Venous thromboembolism prevention during asparaginase-based therapy for acute lymphoblastic leukemia

P500: A REAL WORLD MULTI CENTRE STUDY OF CPX‐351 REVEALS NO DIFFERENCE IN OVERALL SURVIVAL WHEN COMPARED WITH FLAG‐IDA AND 3 + 7 IN HIGH RISK AML

Critical Role for Fas-Associated Death Domain–Like Interleukin-1–Converting Enzyme–Like Inhibitory Protein in Anoikis Resistance and Distant Tumor Formation

The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2

Busulfan and cyclophosphamide as a preparative regimen for allogeneic blood and marrow transplantation in patients with non-Hodgkin's lymphoma

Treatment of elderly patients with acute lymphoblastic leukemia—Evidence for a benefit of imatinib in BCR-ABL positive patients

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