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Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody

Frontiers in immunology, 2022-08, Vol.13, p.957874-957874

2022

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Enhancing CDC and ADCC of CD19 Antibodies by Combining Fc Protein-Engineering with Fc Glyco-Engineering

Antibodies (Basel), 2020-11, Vol.9 (4), p.63

2020

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Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo

Journal of clinical medicine, 2021-06, Vol.10 (12), p.2634

2021

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COVID-19: Would compulsory vaccination be legally possible?

Deutsche medizinische Wochenschrift (1946), 2021-02, Vol.146 (3), p.206

2021

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COVID-19: Wäre eine Impfpflicht rechtlich möglich?

Deutsche medizinische Wochenschrift, 2021-02, Vol.146 (3), p.206-208

2021

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Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL

Blood, 2022-07, Vol.140 (1), p.45-57

2022

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Combination Analysis of Activator Protein-1 Family Members, Sp1 and an Activator Protein-2α-Related Factor Binding to Different Regions of the Urokinase Receptor Gene in Resected Colorectal Cancers

Clinical cancer research, 2005-12, Vol.11 (24), p.8538-8548

2005

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CNS Invasion of TCF3::PBX1 + Leukemia Cells Requires Upregulation of AP-1 Signaling As Revealed By Brain Organoid Model

Blood, 2023-11, Vol.142 (Supplement 1), p.1407-1407

2023

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IL7R Targeting Using OSE-127 Shows Robust Anti-Leukemic Activity in B-Cell Precursor Acute Lymphoblastic Leukemia Xenografts

Blood, 2021-11, Vol.138 (Supplement 1), p.1313-1313

2021

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The IL7R-Antagonist OSE-127 Blocks Acute Lymphoblastic Leukemia Development Via a Dual Mode of Action

Blood, 2022-11, Vol.140 (Supplement 1), p.1045-1047

2022

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A Novel Fc-Optimized Antibody Drug Conjugate Targeting CD7 As a Therapeutic Strategy in T-Cell Acute Lymphoblastic Leukemia

Blood, 2023-11, Vol.142 (Supplement 1), p.4190-4190

2023

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Methotrexate-Associated Toxicity in Children with Down Syndrome and Acute Lymphoblastic Leukemia during Consolidation Therapy with High Dose Methotrexate According to ALL-BFM Treatment Regimen

Blood, 2018-11, Vol.132 (Supplement 1), p.1378-1378

2018

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Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B Cell Precursor Acute Lymphoblastic Leukemia

Blood, 2021-11, Vol.138 (Supplement 1), p.2388-2388

2021

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Blockade of CD47-Sirpα Interactions Improved Myeloid Effector Cell Mediated Lymphoma Cell Killing By the HLA-DR Antibody Apolizumab

Blood, 2019-11, Vol.134 (Supplement_1), p.5305-5305

2019

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Co-Targeting of CD38 and CD47 in T Cell Acute Lymphoblastic Leukemia

Blood, 2020-11, Vol.136 (Supplement 1), p.39-40

2020

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CD79a Is Associated with Central Nervous System Infiltration of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Blood, 2018-11, Vol.132 (Supplement 1), p.386-386

2018

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Venetoclax Enhances the Efficacy of Therapeutic Antibodies in B-Cell Malignancies

Blood, 2018-11, Vol.132 (Supplement 1), p.4177-4177

2018

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Tumor-specific Transcription Factor Binding to an Activator Protein-2/Sp1 Element of the Urokinase-type Plasminogen Activator Receptor Promoter in a First Large Series of Resected Gastrointestinal Cancers

Clinical cancer research, 2003-06, Vol.9 (6), p.2267-2276

2003

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Zeta-Chain-Associated Protein Kinase-70 (Zap-70) Promotes Acute Lymphoblastic Leukemia (ALL) Infiltration into the Central Nervous System By Enhancing Chemokine Receptor 7 (CCR7) Expression

Blood, 2015-12, Vol.126 (23), p.901-901

2015

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Targeting of the Interleukin-7 Receptor Alpha-Chain (IL-7Rα) Blocks B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Development and Reduces Leukemic Infiltration to the Central Nervous System (CNS)

Blood, 2017-12, Vol.130, p.479-479

2017

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Frequent and reliable engraftment of certain adult primary acute lymphoblastic leukemias in mice

Leukemia & lymphoma, 2019-02, Vol.60 (3), p.848-851

2019

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Constitutive Activation of FLT3 Is a Positive Prognostic Factor in Infants with MLL-Rearranged Acute Lymphoblastic Leukemia

Blood, 2015-12, Vol.126 (23), p.1417-1417

2015

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Analyses of a Pair of Concordant Twins with Infant ALL and Discordant Clinical Outcome Reveals Immunoescape As a Mechanism of Disease Persistence in MLL-Rearranged Leukemia

Blood, 2014-12, Vol.124 (21), p.3791-3791

2014

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Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody

Enhancing CDC and ADCC of CD19 Antibodies by Combining Fc Protein-Engineering with Fc Glyco-Engineering

Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo

COVID-19: Would compulsory vaccination be legally possible?

COVID-19: Wäre eine Impfpflicht rechtlich möglich?

Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL

Combination Analysis of Activator Protein-1 Family Members, Sp1 and an Activator Protein-2α-Related Factor Binding to Different Regions of the Urokinase Receptor Gene in Resected Colorectal Cancers

CNS Invasion of TCF3::PBX1 + Leukemia Cells Requires Upregulation of AP-1 Signaling As Revealed By Brain Organoid Model

IL7R Targeting Using OSE-127 Shows Robust Anti-Leukemic Activity in B-Cell Precursor Acute Lymphoblastic Leukemia Xenografts

The IL7R-Antagonist OSE-127 Blocks Acute Lymphoblastic Leukemia Development Via a Dual Mode of Action

A Novel Fc-Optimized Antibody Drug Conjugate Targeting CD7 As a Therapeutic Strategy in T-Cell Acute Lymphoblastic Leukemia

Methotrexate-Associated Toxicity in Children with Down Syndrome and Acute Lymphoblastic Leukemia during Consolidation Therapy with High Dose Methotrexate According to ALL-BFM Treatment Regimen

Preclinical Evidence for the Efficacy of CD79b Immunotherapy in B Cell Precursor Acute Lymphoblastic Leukemia

Isocitrate dehydrogenase 1 mutation drives leukemogenesis by PDGFRA activation due to insulator disruption in acute myeloid leukemia (AML)

Blockade of CD47-Sirpα Interactions Improved Myeloid Effector Cell Mediated Lymphoma Cell Killing By the HLA-DR Antibody Apolizumab

Co-Targeting of CD38 and CD47 in T Cell Acute Lymphoblastic Leukemia

CD79a Is Associated with Central Nervous System Infiltration of Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Venetoclax Enhances the Efficacy of Therapeutic Antibodies in B-Cell Malignancies

Tumor-specific Transcription Factor Binding to an Activator Protein-2/Sp1 Element of the Urokinase-type Plasminogen Activator Receptor Promoter in a First Large Series of Resected Gastrointestinal Cancers

Zeta-Chain-Associated Protein Kinase-70 (Zap-70) Promotes Acute Lymphoblastic Leukemia (ALL) Infiltration into the Central Nervous System By Enhancing Chemokine Receptor 7 (CCR7) Expression

Poor Prognosis in Children with ABL-Class Fusion Positive B-Cell Acute Lymphoblastic Leukemia Treated According to AIEOP-BFM Protocols

Targeting of the Interleukin-7 Receptor Alpha-Chain (IL-7Rα) Blocks B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Development and Reduces Leukemic Infiltration to the Central Nervous System (CNS)

Frequent and reliable engraftment of certain adult primary acute lymphoblastic leukemias in mice

Constitutive Activation of FLT3 Is a Positive Prognostic Factor in Infants with MLL-Rearranged Acute Lymphoblastic Leukemia

Analyses of a Pair of Concordant Twins with Infant ALL and Discordant Clinical Outcome Reveals Immunoescape As a Mechanism of Disease Persistence in MLL-Rearranged Leukemia

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