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Strategies To Deliver Peptide Drugs to the Brain

Molecular pharmaceutics, 2014-04, Vol.11 (4), p.1081-1093

2014

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A polymeric aqueous tacrolimus formulation for topical ocular delivery

International journal of pharmaceutics, 2021-04, Vol.599, p.120364-120364, Article 120364

2021

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Dose-dependent delivery of genes to the cerebral cortex via the nasal route

International journal of pharmaceutics, 2023-09, Vol.644, p.123343-123343, Article 123343

2023

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Nanoparticulate peptide delivery exclusively to the brain produces tolerance free analgesia

Journal of controlled release, 2018-01, Vol.270, p.135-144

2018

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SARS-CoV-2 inhibition using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray

Scientific reports, 2021-10, Vol.11 (1), p.20012-11, Article 20012

2021

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The topical ocular delivery of rapamycin to posterior eye tissues and the suppression of retinal inflammatory disease

International journal of pharmaceutics, 2022-06, Vol.621, p.121755, Article 121755

2022

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Tissue-Engineering the Fibrous Pancreatic Tumour Stroma Capsule in 3D Tumouroids to Demonstrate Paclitaxel Response

International journal of molecular sciences, 2021-04, Vol.22 (8), p.4289

2021

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Down-regulation of GP130 signaling sensitizes bladder cancer to cisplatin by impairing Ku70 DNA repair signaling and promoting apoptosis

Cellular signalling, 2021-05, Vol.81, p.109931-109931, Article 109931

2021

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Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure

International journal of pharmaceutics, 2022-04, Vol.618, p.121658-121658, Article 121658

2022

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Gene Targeting to the Cerebral Cortex Following Intranasal Administration of Polyplexes

Pharmaceutics, 2022-05, Vol.14 (6), p.1136

2022

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Polymeric Micelles for the Enhanced Deposition of Hydrophobic Drugs into Ocular Tissues, without Plasma Exposure

Pharmaceutics, 2021-05, Vol.13 (5), p.744

2021

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Clustering superparamagnetic iron oxide nanoparticles produces organ-targeted high-contrast magnetic resonance images

Nanomedicine (London, England), 2019-05, Vol.14 (9), p.1135-1152

2019

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Nose-to-Brain Delivery

The Journal of pharmacology and experimental therapeutics, 2019-09, Vol.370 (3), p.593-601

2019

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Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels – A Strategy for Brain Cancer Treatments

Pharmaceutical research, 2016-05, Vol.33 (5), p.1289-1303

2016

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Cancer-specific transgene expression mediated by systemic injection of nanoparticles

Cancer research (Chicago, Ill.), 2009-03, Vol.69 (6), p.2655-2662

2009

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Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate

International journal of pharmaceutics, 2016-11, Vol.514 (1), p.121-132

2016

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Limiting the level of tertiary amines on polyamines leads to biocompatible nucleic acid vectors

International journal of pharmaceutics, 2017-06, Vol.526 (1-2), p.106-124

2017

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A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo

The Journal of clinical investigation, 2007-04, Vol.117 (4), p.1008-1018

2007

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Dendrimers in gene delivery

Advanced drug delivery reviews, 2005-12, Vol.57 (15), p.2177-2202

2005

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Brain Gene Silencing with Cationic Amino-Capped Poly(ethylene glycol) Polyplexes

Biomedicines, 2022-09, Vol.10 (9), p.2182

2022

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Amphotericin B Polymer Nanoparticles Show Efficacy against Candida Species Biofilms

Pathogens (Basel), 2022-01, Vol.11 (1), p.73

2022

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Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC ® Natural Adjuvant against Aspergillosis

Pharmaceutics, 2019-09, Vol.11 (9), p.456

2019

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In silico modelling of drug-polymer interactions for pharmaceutical formulations

Journal of the Royal Society interface, 2010-08, Vol.7 Suppl 4 (suppl_4), p.S423

2010

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High-capacity glycol chitosan-based nanoemulsion for efficient delivery of disulfiram

International journal of pharmaceutics, 2023-06, Vol.640, p.123036-123036, Article 123036

2023

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Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule

Scientific reports, 2013-09, Vol.3 (1), p.2799, Article 2799

2013

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Strategies To Deliver Peptide Drugs to the Brain

A polymeric aqueous tacrolimus formulation for topical ocular delivery

Dose-dependent delivery of genes to the cerebral cortex via the nasal route

Nanoparticulate peptide delivery exclusively to the brain produces tolerance free analgesia

SARS-CoV-2 inhibition using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray

The topical ocular delivery of rapamycin to posterior eye tissues and the suppression of retinal inflammatory disease

Tissue-Engineering the Fibrous Pancreatic Tumour Stroma Capsule in 3D Tumouroids to Demonstrate Paclitaxel Response

Down-regulation of GP130 signaling sensitizes bladder cancer to cisplatin by impairing Ku70 DNA repair signaling and promoting apoptosis

Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure

Gene Targeting to the Cerebral Cortex Following Intranasal Administration of Polyplexes

Polymeric Micelles for the Enhanced Deposition of Hydrophobic Drugs into Ocular Tissues, without Plasma Exposure

Clustering superparamagnetic iron oxide nanoparticles produces organ-targeted high-contrast magnetic resonance images

Nose-to-Brain Delivery

Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels – A Strategy for Brain Cancer Treatments

Cancer-specific transgene expression mediated by systemic injection of nanoparticles

Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate

Limiting the level of tertiary amines on polyamines leads to biocompatible nucleic acid vectors

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo

Dendrimers in gene delivery

Brain Gene Silencing with Cationic Amino-Capped Poly(ethylene glycol) Polyplexes

Amphotericin B Polymer Nanoparticles Show Efficacy against Candida Species Biofilms

Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC ® Natural Adjuvant against Aspergillosis

In silico modelling of drug-polymer interactions for pharmaceutical formulations

High-capacity glycol chitosan-based nanoemulsion for efficient delivery of disulfiram

Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule

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