UB Paderborn / Katalog / Suche / in CDI

Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression

Cancer research (Chicago, Ill.), 2008-12, Vol.68 (23), p.9788-9798

2008

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S286: TARGETING CONDITIONING‐ELICITED NON‐TRANSFERRIN‐BOUND IRON BY TMPRSS6 SILENCING IMPROVES BONE MARROW TRANSPLANT OUTCOME

HemaSphere, 2023-08, Vol.7 (S3), p.e60448cb-n/a

2023

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miR-150-PTPMT1-cardiolipin signaling in pulmonary arterial hypertension

Molecular therapy. Nucleic acids, 2021-03, Vol.23, p.142-153

2021

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Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models

Clinical cancer research, 2010-11, Vol.16 (22), p.5469-5480

2010

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CLIC4/Arf6 Pathway

Circulation research, 2019-01, Vol.124 (1), p.52-65

2019

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SLN124, a GalNAc‐siRNA Conjugate Targeting TMPRSS6, Efficiently Prevents Iron Overload in Hereditary Haemochromatosis Type 1

HemaSphere, 2019-12, Vol.3 (6), p.e301-n/a

2019

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Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (39), p.15376-15381

2007

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Coupling of Gab1 to c-Met, Grb2, and Shp2 Mediates Biological Responses

The Journal of cell biology, 2000-06, Vol.149 (7), p.1419-1432

2000

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Repin1 deficiency in liver tissue alleviates NAFLD progression in mice

Journal of advanced research, 2019-03, Vol.16, p.99-111

2019

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Essential Role of Gab1 for Signaling by the c-Met Receptor in Vivo

The Journal of cell biology, 2000-09, Vol.150 (6), p.1375-1384

2000

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Foxf1 siRNA delivery to hepatic stellate cells by DBTC lipoplex formulations ameliorates fibrosis in livers of bile duct ligated mice

Current gene therapy, 2015-01, Vol.15 (3), p.215

2015

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The Docking Protein Gab1 Is an Essential Component of an Indirect Mechanism for Fibroblast Growth Factor Stimulation of the Phosphatidylinositol 3-Kinase/Akt Antiapoptotic Pathway

Molecular and Cellular Biology, 2004-07, Vol.24 (13), p.5657-5666

2004

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Interaction between a Cellular Protein That Binds to the C-terminal Region of Adenovirus E1A (CtBP) and a Novel Cellular Protein Is Disrupted by E1A through a Conserved PLDLS Motif

The Journal of biological chemistry, 1998-04, Vol.273 (15), p.8549-8552

1998

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Signaling of Hepatocyte Growth Factor/Scatter Factor (HGF) to the Small GTPase Rap1 via the Large Docking Protein Gab1 and the Adapter Protein CRKL

The Journal of biological chemistry, 2000-04, Vol.275 (15), p.10772-10778

2000

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Liver-specific Bid silencing inhibits APAP-induced cell death in mice

Apoptosis (London), 2019-12, Vol.24 (11-12), p.934-945

2019

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Tmprss6 Depletion-Mediated Iron Deficiency Attenuates the Clinical Course of Plasmodium Berghei Infection in Mice

Blood, 2022-11, Vol.140 (Supplement 1), p.8186-8187

2022

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The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif

Oncogene, 2001-03, Vol.20 (9), p.1052-1062

2001

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Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis

Cell reports (Cambridge), 2021-05, Vol.35 (8), p.109168-109168, Article 109168

2021

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SLN124, a GalNac‐siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron‐overload in a mouse model of β‐thalassaemia

British journal of haematology, 2021-07, Vol.194 (1), p.200-210

2021

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SLN124, a GalNAc Conjugated 19-Mer Double-Stranded SiRNA Reduces Iron and Increases Hepcidin Levels of Healthy Volunteers in a Phase 1 Clinical Study

Blood, 2021-11, Vol.138 (Supplement 1), p.2009-2009

2021

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SLN124, a GalNAc conjugated 19‐mer siRNA targeting tmprss6, reduces plasma iron and increases hepcidin levels of healthy volunteers

American journal of hematology, 2023-09, Vol.98 (9), p.1425-1435

2023

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SLN140 a Small Interfering RNA Targeting Protein S Improves Hemostasis Potency in Hemophilia

Blood, 2022-11, Vol.140 (Supplement 1), p.1670-1671

2022

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Lung-Targeted RNA Interference Against Angiopoietin-2 Ameliorates Multiple Organ Dysfunction and Death in Sepsis

Critical care medicine, 2014-10, Vol.42 (10), p.e654-e662

2014

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CLIC4/Arf6 Pathway: A New Lead in BMPRII Inhibition in Pulmonary Hypertension

Circulation research, 2019-01, Vol.124 (1), p.52-65

2019

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Targeting cyclin M4 as a new therapeutical approach to treat alcoholic liver disease

Journal of hepatology, 2022-07, Vol.77, p.S132-S133

2022

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Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression

S286: TARGETING CONDITIONING‐ELICITED NON‐TRANSFERRIN‐BOUND IRON BY TMPRSS6 SILENCING IMPROVES BONE MARROW TRANSPLANT OUTCOME

miR-150-PTPMT1-cardiolipin signaling in pulmonary arterial hypertension

Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models

CLIC4/Arf6 Pathway

SLN124, a GalNAc‐siRNA Conjugate Targeting TMPRSS6, Efficiently Prevents Iron Overload in Hereditary Haemochromatosis Type 1

Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo

Coupling of Gab1 to c-Met, Grb2, and Shp2 Mediates Biological Responses

Repin1 deficiency in liver tissue alleviates NAFLD progression in mice

Essential Role of Gab1 for Signaling by the c-Met Receptor in Vivo

Foxf1 siRNA delivery to hepatic stellate cells by DBTC lipoplex formulations ameliorates fibrosis in livers of bile duct ligated mice

The Docking Protein Gab1 Is an Essential Component of an Indirect Mechanism for Fibroblast Growth Factor Stimulation of the Phosphatidylinositol 3-Kinase/Akt Antiapoptotic Pathway

Interaction between a Cellular Protein That Binds to the C-terminal Region of Adenovirus E1A (CtBP) and a Novel Cellular Protein Is Disrupted by E1A through a Conserved PLDLS Motif

Signaling of Hepatocyte Growth Factor/Scatter Factor (HGF) to the Small GTPase Rap1 via the Large Docking Protein Gab1 and the Adapter Protein CRKL

Liver-specific Bid silencing inhibits APAP-induced cell death in mice

Tmprss6 Depletion-Mediated Iron Deficiency Attenuates the Clinical Course of Plasmodium Berghei Infection in Mice

The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif

Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis

SLN124, a GalNac‐siRNA targeting transmembrane serine protease 6, in combination with deferiprone therapy reduces ineffective erythropoiesis and hepatic iron‐overload in a mouse model of β‐thalassaemia

SLN124, a GalNAc Conjugated 19-Mer Double-Stranded SiRNA Reduces Iron and Increases Hepcidin Levels of Healthy Volunteers in a Phase 1 Clinical Study

SLN124, a GalNAc conjugated 19‐mer siRNA targeting tmprss6, reduces plasma iron and increases hepcidin levels of healthy volunteers

SLN140 a Small Interfering RNA Targeting Protein S Improves Hemostasis Potency in Hemophilia

Lung-Targeted RNA Interference Against Angiopoietin-2 Ameliorates Multiple Organ Dysfunction and Death in Sepsis

CLIC4/Arf6 Pathway: A New Lead in BMPRII Inhibition in Pulmonary Hypertension

Targeting cyclin M4 as a new therapeutical approach to treat alcoholic liver disease

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