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DNA Methylation of ADME Genes

Clinical pharmacology and therapeutics, 2016-05, Vol.99 (5), p.512-527

2016

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Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium

Clinical pharmacology and therapeutics, 2017-03, Vol.101 (3), p.341-358

2017

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Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer

The pharmacogenomics journal, 2015-02, Vol.15 (1), p.84-94

2015

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Polymorphic Variation in TPMT Is the Principal Determinant of TPMT Phenotype: A Meta‐Analysis of Three Genome‐Wide Association Studies

Clinical pharmacology and therapeutics, 2017-05, Vol.101 (5), p.684-695

2017

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Genetic variation of platelet function and pharmacology: an update of current knowledge

Thrombosis and haemostasis, 2013, Vol.110 (5), p.876

2013

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Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

The pharmacogenomics journal, 2016-08, Vol.16 (4), p.341-351

2016

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Stratified medicine for the use of antidiabetic medication in treatment of type II diabetes and cancer: where do we go from here?

Journal of internal medicine, 2015-02, Vol.277 (2), p.235-247

2015

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Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1

The pharmacogenomics journal, 2016-11, Vol.16 (6), p.551-558

2016

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ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation

Journal of the American Society of Nephrology, 2005-05, Vol.16 (5), p.1501-1511

2005

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Immunological markers and somatic mutations as predictors for therapy selection in metastatic renal cell carcinoma

European urology open science (Online), 2022-08, Vol.42, p.S34

2022

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Adherence to thiopurine treatment in out‐patients with Crohn’s disease

Alimentary pharmacology & therapeutics, 2007-07, Vol.26 (2), p.217-225

2007

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Variability in human hepatic MRP4 expression: influence of cholestasis and genotype

The pharmacogenomics journal, 2008-02, Vol.8 (1), p.42-52

2008

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ABCB1 Single‐Nucleotide Polymorphisms Determine Tacrolimus Response in Patients With Ulcerative Colitis

Clinical pharmacology and therapeutics, 2011-03, Vol.89 (3), p.422-428

2011

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Functional characterization of common protein variants in the efflux transporter ABCC11 and identification of T546M as functionally damaging variant

The pharmacogenomics journal, 2016-04, Vol.16 (2), p.193-201

2016

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Clinical and Functional Relevance of the Monocarboxylate Transporter Family in Disease Pathophysiology and Drug Therapy

Clinical and translational science, 2018-07, Vol.11 (4), p.352-364

2018

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Targeted Exome Resequencing: Adme Pharmacogenetics In Human Liver

Clinical therapeutics, 2015-08, Vol.37 (8), p.e71-e71

2015

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Adme-wide analysis of Copy Number Variation using Targeted exome resequencing and their functional relevance in Human Liver

Clinical therapeutics, 2015-08, Vol.37 (8), p.e104-e104

2015

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Safe treatment of thiopurine S-methyltransferase deficient Crohn’s disease patients with azathioprine

Gut, 2003-01, Vol.52 (1), p.140-142

2003

Volltextzugriff (PDF)

CD147, The Ancillary protein of MCT4, as marker for prognosis and clinical outcome in primary clear cell renal cell Carcinoma and Metastasis

Clinical therapeutics, 2015-08, Vol.37 (8), p.e75-e76

2015

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Challenges and opportunities associated with rare-variant pharmacogenomics

Trends in pharmacological sciences (Regular ed.), 2022-10, Vol.43 (10), p.852-865

2022

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Human Pregnane X Receptor Genotype of the Donor but Not of the Recipient Is a Risk Factor for Delayed Graft Function After Renal Transplantation

Clinical pharmacology and therapeutics, 2012-05, Vol.91 (5), p.905-916

2012

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Pretreatment determination of TPMT - state of the art in clinical practice

European journal of clinical pharmacology, 2009-03, Vol.65 (3), p.219-221

2009

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Germline variant burden in multidrug resistance transporters is a therapy‐specific predictor of survival in breast cancer patients

International journal of cancer, 2020-05, Vol.146 (9), p.2475-2487

2020

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Reduced Paneth Cell α-Defensins in Ileal Crohn's Disease

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (50), p.18129-18134

2005

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Combination of high on-treatment platelet aggregation and low deaggregation better predicts long-term cardiovascular events in PCI patients under dual antiplatelet therapy

Platelets (Edinburgh), 2014-01, Vol.25 (6), p.439-446

2014

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DNA Methylation of ADME Genes

Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium

Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer

Polymorphic Variation in TPMT Is the Principal Determinant of TPMT Phenotype: A Meta‐Analysis of Three Genome‐Wide Association Studies

Genetic variation of platelet function and pharmacology: an update of current knowledge

Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors

Stratified medicine for the use of antidiabetic medication in treatment of type II diabetes and cancer: where do we go from here?

Gene copy number variation analysis reveals dosage-insensitive expression of CYP2E1

ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation

Immunological markers and somatic mutations as predictors for therapy selection in metastatic renal cell carcinoma

Adherence to thiopurine treatment in out‐patients with Crohn’s disease

Variability in human hepatic MRP4 expression: influence of cholestasis and genotype

ABCB1 Single‐Nucleotide Polymorphisms Determine Tacrolimus Response in Patients With Ulcerative Colitis

Functional characterization of common protein variants in the efflux transporter ABCC11 and identification of T546M as functionally damaging variant

Clinical and Functional Relevance of the Monocarboxylate Transporter Family in Disease Pathophysiology and Drug Therapy

Targeted Exome Resequencing: Adme Pharmacogenetics In Human Liver

Adme-wide analysis of Copy Number Variation using Targeted exome resequencing and their functional relevance in Human Liver

Safe treatment of thiopurine S-methyltransferase deficient Crohn’s disease patients with azathioprine

CD147, The Ancillary protein of MCT4, as marker for prognosis and clinical outcome in primary clear cell renal cell Carcinoma and Metastasis

Challenges and opportunities associated with rare-variant pharmacogenomics

Human Pregnane X Receptor Genotype of the Donor but Not of the Recipient Is a Risk Factor for Delayed Graft Function After Renal Transplantation

Pretreatment determination of TPMT - state of the art in clinical practice

Germline variant burden in multidrug resistance transporters is a therapy‐specific predictor of survival in breast cancer patients

Reduced Paneth Cell α-Defensins in Ileal Crohn's Disease

Combination of high on-treatment platelet aggregation and low deaggregation better predicts long-term cardiovascular events in PCI patients under dual antiplatelet therapy

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