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Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer

Lung cancer (Amsterdam, Netherlands), 2020-01, Vol.139, p.60-67

2020

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Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (23), p.9937-9948

2010

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Therapeutic Targeting of Nuclear Export Inhibition in Lung Cancer

Journal of thoracic oncology, 2017-09, Vol.12 (9), p.1446-1450

2017

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Patterns of Failure in Patients With Double Hit or Double Expressor Lymphomas: Implications for Radiation Therapy

International journal of radiation oncology, biology, physics, 2018-04, Vol.100 (5), p.1126-1132

2018

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Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice

Human gene therapy, 2001-05, Vol.12 (7), p.799-809

2001

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Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone

Cancer & metabolism, 2015-10, Vol.3 (1), p.12-12, Article 12

2015

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CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor

Molecular and cellular biochemistry, 2008-09, Vol.316 (1-2), p.149-154

2008

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Abstract B22: Acyl-CoA synthetase long-chain family member 3 dependent lipid homeostasis is required for mutant KRAS driven lung cancer

Molecular cancer research, 2016-01, Vol.14 (1_Supplement), p.B22-B22

2016

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Treatment of adolescent young adults with acute lymphoblastic leukemia: 10-year outcome data from a single institution

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.e18047-e18047

2015

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Impact of body mass index and ethnicity on asparaginase toxicity in adult acute lymphoblastic leukemia patients

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.e18051-e18051

2015

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Clinical outcome of adult acute lymphoblastic leukemia based on Philadelphia chromosome status and socioeconomic status

Journal of clinical oncology, 2015-05, Vol.33 (15_suppl), p.7083-7083

2015

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A phase 2 study of defactinib (VS-6063), a cancer stem cell inhibitor that acts through inhibition of focal adhesion kinase (FAK), in patients with KRAS-mutant non-small cell lung cancer

Journal of clinical oncology, 2014-05, Vol.32 (15_suppl), p.TPS8126-TPS8126

2014

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A CK2-Dependent Mechanism for PML Degradation upon Cellular and Oncogenic Stress

Blood, 2006-11, Vol.108 (11), p.1426-1426

2006

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Activation of the P38 MAPK Pathway Results in Ubiquitin-Proteasome Degradation of the PML Tumor Suppressor Protein

Blood, 2004-11, Vol.104 (11), p.2553-2553

2004

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Loss of the tumor suppressor PML in human cancers of multiple histologic origins

JNCI : Journal of the National Cancer Institute, 2004-02, Vol.96 (4), p.269-279

2004

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Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective

Hepatology (Baltimore, Md.), 1998-02, Vol.27 (2), p.628-633

1998

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Cloning and Characterization of a Novel Hepatitis B Virus x Binding Protein That Inhibits Viral Replication

Journal of Virology, 1998-03, Vol.72 (3), p.1737-1743

1998

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Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

Cancer discovery, 2021-11, Vol.11 (11), p.2904-2923

2021

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The theory of APL revisited

Current topics in microbiology and immunology, 2007, Vol.313, p.85

2007

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Posttranscriptional regulation of hepatitis B virus replication by the precore protein

Journal of Virology, 1997-01, Vol.71 (1), p.345-353

1997

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Biologic Properties of Hepatitis B Viral Genomes with Mutations in the Precore Promoter and Precore Open Reading Frame

Virology (New York, N.Y.), 1997-07, Vol.233 (2), p.374-381

1997

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In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia

The Journal of experimental medicine, 2006-04, Vol.203 (4), p.821-828

2006

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Medicine Taking apart a cancer protein

Nature, 2003-12, Vol.426 (6966), p.512-513

2003

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The small envelope protein is required for secretion of a naturally occurring hepatitis B virus mutant with pre-S1 deleted

Journal of Virology, 1997-07, Vol.71 (7), p.5449-5454

1997

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Treatment with 5-azacytidine accelerates acute promyelocytic leukemia leukemogenesis in a transgenic mouse model

Genes & cancer, 2011-02, Vol.2 (2), p.160-165

2011

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Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer

Aldehyde Dehydrogenase Activity Selects for Lung Adenocarcinoma Stem Cells Dependent on Notch Signaling

Therapeutic Targeting of Nuclear Export Inhibition in Lung Cancer

Patterns of Failure in Patients With Double Hit or Double Expressor Lymphomas: Implications for Radiation Therapy

Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone

CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor

Abstract B22: Acyl-CoA synthetase long-chain family member 3 dependent lipid homeostasis is required for mutant KRAS driven lung cancer

Treatment of adolescent young adults with acute lymphoblastic leukemia: 10-year outcome data from a single institution

Impact of body mass index and ethnicity on asparaginase toxicity in adult acute lymphoblastic leukemia patients

Clinical outcome of adult acute lymphoblastic leukemia based on Philadelphia chromosome status and socioeconomic status

A phase 2 study of defactinib (VS-6063), a cancer stem cell inhibitor that acts through inhibition of focal adhesion kinase (FAK), in patients with KRAS-mutant non-small cell lung cancer

A CK2-Dependent Mechanism for PML Degradation upon Cellular and Oncogenic Stress

Activation of the P38 MAPK Pathway Results in Ubiquitin-Proteasome Degradation of the PML Tumor Suppressor Protein

Loss of the tumor suppressor PML in human cancers of multiple histologic origins

Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective

Cloning and Characterization of a Novel Hepatitis B Virus x Binding Protein That Inhibits Viral Replication

Medium-Chain Acyl-CoA Dehydrogenase Protects Mitochondria from Lipid Peroxidation in Glioblastoma

The theory of APL revisited

Posttranscriptional regulation of hepatitis B virus replication by the precore protein

Biologic Properties of Hepatitis B Viral Genomes with Mutations in the Precore Promoter and Precore Open Reading Frame

In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia

Medicine Taking apart a cancer protein

The small envelope protein is required for secretion of a naturally occurring hepatitis B virus mutant with pre-S1 deleted

Treatment with 5-azacytidine accelerates acute promyelocytic leukemia leukemogenesis in a transgenic mouse model

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