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Dose–response and Cardiopulmonary Side Effects of the Novel Neuromuscular-blocking Drug CW002 in Man

Anesthesiology (Philadelphia), 2016-12, Vol.125 (6), p.1136-1143

2016

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Pharmacodynamics and Cardiopulmonary Side Effects of CW002, a Cysteine-reversible Neuromuscular Blocking Drug in Dogs

Anesthesiology (Philadelphia), 2010-04, Vol.112 (4), p.910-916

2010

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Clinical pharmacology of GW280430A in humans

Anesthesiology (Philadelphia), 2004-04, Vol.100 (4), p.768-773

2004

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Gantacurium and CW002 Do Not Potentiate Muscarinic Receptor-mediated Airway Smooth Muscle Constriction in Guinea Pigs

Anesthesiology (Philadelphia), 2010-04, Vol.112 (4), p.892-899

2010

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Preclinical Pharmacology in the Rhesus Monkey of CW 1759-50, a New Ultra-short Acting Nondepolarizing Neuromuscular Blocking Agent, Degraded and Antagonized by L-Cysteine

Anesthesiology (Philadelphia), 2018-11, Vol.129 (5), p.970-988

2018

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Fumarates: Unique nondepolarizing neuromuscular blocking agents that are antagonized by cysteine

Journal of critical care, 2009-03, Vol.24 (1), p.50-57

2009

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Pharmacokinetic/Pharmacodynamic Model of CW002, an Investigational Intermediate Neuromuscular Blocking Agent, in Healthy Volunteers

Anesthesiology (Philadelphia), 2018-06, Vol.128 (6), p.1107-1116

2018

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Novel neuromuscular blocking drugs and antagonists

Current opinion in anaesthesiology, 2015-08, Vol.28 (4), p.403-410

2015

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Preclinical Pharmacology of CW002: A Nondepolarizing Neuromuscular Blocking Drug of Intermediate Duration, Degraded and Antagonized by l-cysteine—Additional Studies of Safety and Efficacy in the Anesthetized Rhesus Monkey and Cat

Anesthesiology (Philadelphia), 2016-10, Vol.125 (4), p.732-743

2016

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Cardiopulmonary effects of the novel neuromuscular blocking drug GW280430A (AV430A) in dogs

Anesthesiology (Philadelphia), 2004-04, Vol.100 (4), p.846-851

2004

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Noninvasive cardiac output monitoring with bioreactance as an alternative to invasive instrumentation for preclinical drug evaluation in beagles

Journal of pharmacological and toxicological methods, 2011-09, Vol.64 (2), p.111-118

2011

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Rapid Chemical Antagonism of Neuromuscular Blockade by L-Cysteine Adduction to and Inactivation of the Olefinic (Double-bonded) Isoquinolinium Diester Compounds Gantacurium (AV430A), CW 002, and CW 011

Anesthesiology (Philadelphia), 2010-07, Vol.113 (1), p.58-73

2010

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Cysteine Reversal of the Novel Neuromuscular Blocking Drug CW002 in Dogs: Pharmacodynamics, Acute Cardiovascular Effects, and Preliminary Toxicology

Anesthesiology (Philadelphia), 2010-04, Vol.112 (4), p.900-909

2010

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Bis- and Mixed-Tetrahydroisoquinolinium Chlorofumarates: New Ultra-Short-Acting Nondepolarizing Neuromuscular Blockers

Journal of medicinal chemistry, 1999-01, Vol.42 (2), p.206-209

1999

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Preclinical pharmacology of GW280430A (AV430A) in the rhesus monkey and in the cat: A comparison with mivacurium

Anesthesiology (Philadelphia), 2004-04, Vol.100 (4), p.835-845

2004

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Optimizing Alkali-cellulase Processing of Biomass into Glucose

Bioresources, 2013-01, Vol.8 (4)

Savarese, John J.

2013

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Continuous Alkali-Cellulase Processing of Corn Stover to Glucose for Bioethanol

Bioresources, 2013-01, Vol.8 (4)

Savarese, John J.

2013

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The Clinical Neuromuscular Pharmacology of Mivacurium Chloride (BW B1090U). A Short-acting Nondepolarizing Ester Neuromuscular Blocking Drug

Anesthesiology (Philadelphia), 1988-05, Vol.68 (5), p.723-732

1988

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Neuromuscular Blocking Activity and Therapeutic Potential of Mixed-Tetrahydroisoquinolinium Halofumarates and Halosuccinates in Rhesus Monkeys

Journal of medicinal chemistry, 2003-06, Vol.46 (12), p.2502-2515

2003

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Preclinical Pharmacology of CW002

Anesthesiology (Philadelphia), 2016-10, Vol.125 (4), p.732-743

2016

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Local Biomass Processing is Practical for Facilitating Fermentation to Bioethanol

Journal of Technology Innovations in Renewable Energy, 2013-08, Vol.2 (3), p.239-245

Savarese, John J.

2013

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Edrophonium effectively antagonizes neuromuscular block at the laryngeal adductors induced by rapacuronium, rocuronium and cisatracurium, but not mivacurium

Canadian journal of anesthesia, 2003-11, Vol.50 (9), p.879-885

2003

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Pharmacodynamics and the plasma concentration of mivacurium during spontaneous recovery and neostigmine-facilitated recovery

Anesthesiology (Philadelphia), 1999-07, Vol.91 (1), p.119-126

1999

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GW280430A: Pharmacodynamics and Potential Adverse Effects

Anesthesiology (Philadelphia), 2005-04, Vol.102 (4), p.863-865

Savarese, John J.

2005

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Noninvasive cardiac output monitoring with bioreactance as an alternative to invasive instrumentation for preclinical drug evaluation in beaglesAU: Heerdt, Paul M

Journal of pharmacological and toxicological methods, 2011-10, Vol.64 (2), p.111-118

2011

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Dose–response and Cardiopulmonary Side Effects of the Novel Neuromuscular-blocking Drug CW002 in Man

Pharmacodynamics and Cardiopulmonary Side Effects of CW002, a Cysteine-reversible Neuromuscular Blocking Drug in Dogs

Clinical pharmacology of GW280430A in humans

Gantacurium and CW002 Do Not Potentiate Muscarinic Receptor-mediated Airway Smooth Muscle Constriction in Guinea Pigs

Preclinical Pharmacology in the Rhesus Monkey of CW 1759-50, a New Ultra-short Acting Nondepolarizing Neuromuscular Blocking Agent, Degraded and Antagonized by L-Cysteine

Fumarates: Unique nondepolarizing neuromuscular blocking agents that are antagonized by cysteine

Pharmacokinetic/Pharmacodynamic Model of CW002, an Investigational Intermediate Neuromuscular Blocking Agent, in Healthy Volunteers

Novel neuromuscular blocking drugs and antagonists

Preclinical Pharmacology of CW002: A Nondepolarizing Neuromuscular Blocking Drug of Intermediate Duration, Degraded and Antagonized by l-cysteine—Additional Studies of Safety and Efficacy in the Anesthetized Rhesus Monkey and Cat

Cardiopulmonary effects of the novel neuromuscular blocking drug GW280430A (AV430A) in dogs

Noninvasive cardiac output monitoring with bioreactance as an alternative to invasive instrumentation for preclinical drug evaluation in beagles

Rapid Chemical Antagonism of Neuromuscular Blockade by L-Cysteine Adduction to and Inactivation of the Olefinic (Double-bonded) Isoquinolinium Diester Compounds Gantacurium (AV430A), CW 002, and CW 011

Cysteine Reversal of the Novel Neuromuscular Blocking Drug CW002 in Dogs: Pharmacodynamics, Acute Cardiovascular Effects, and Preliminary Toxicology

Bis- and Mixed-Tetrahydroisoquinolinium Chlorofumarates: New Ultra-Short-Acting Nondepolarizing Neuromuscular Blockers

Preclinical pharmacology of GW280430A (AV430A) in the rhesus monkey and in the cat: A comparison with mivacurium

Optimizing Alkali-cellulase Processing of Biomass into Glucose

Continuous Alkali-Cellulase Processing of Corn Stover to Glucose for Bioethanol

The Clinical Neuromuscular Pharmacology of Mivacurium Chloride (BW B1090U). A Short-acting Nondepolarizing Ester Neuromuscular Blocking Drug

Neuromuscular Blocking Activity and Therapeutic Potential of Mixed-Tetrahydroisoquinolinium Halofumarates and Halosuccinates in Rhesus Monkeys

Preclinical Pharmacology of CW002

Local Biomass Processing is Practical for Facilitating Fermentation to Bioethanol

Edrophonium effectively antagonizes neuromuscular block at the laryngeal adductors induced by rapacuronium, rocuronium and cisatracurium, but not mivacurium

Pharmacodynamics and the plasma concentration of mivacurium during spontaneous recovery and neostigmine-facilitated recovery

GW280430A: Pharmacodynamics and Potential Adverse Effects

Noninvasive cardiac output monitoring with bioreactance as an alternative to invasive instrumentation for preclinical drug evaluation in beaglesAU: Heerdt, Paul M

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