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Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials

Antibiotics (Basel), 2016-02, Vol.5 (1), p.12

2016

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penicillin-binding proteins: structure and role in peptidoglycan biosynthesis

FEMS microbiology reviews, 2008-03, Vol.32 (2), p.234-258

2008

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Understanding the Significance and Implications of Antibody Numbering and Antigen-Binding Surface/Residue Definition

Frontiers in immunology, 2018-10, Vol.9, p.2278-2278

2018

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Crystal structure of penicillin-binding protein 3 (PBP3) from Escherichia coli

PloS one, 2014-05, Vol.9 (5), p.e98042-e98042

2014

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Development of new drugs for an old target: the penicillin binding proteins

Molecules (Basel, Switzerland), 2012-10, Vol.17 (11), p.12478-12505

2012

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Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (44), p.16876-16881

2008

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From "An Enzyme Able to Destroy Penicillin" to Carbapenemases: 70 Years of Beta-lactamase Misbehaviour

Current drug targets, 2016-07, Vol.17 (9), p.974-982

2016

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Crystal structure and kinetic analysis of the class B3 di-zinc metallo-β-lactamase LRA-12 from an Alaskan soil metagenome

PloS one, 2017-07, Vol.12 (7), p.e0182043-e0182043

2017

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A Lysine Cluster in Domain II of Bacillus subtilis PBP4a Plays a Role in the Membrane Attachment of This C1-PBP

PloS one, 2015-10, Vol.10 (10), p.e0140082-e0140082

2015

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Importance of the Conserved Residues in the Peptidoglycan Glycosyltransferase Module of the Class A Penicillin-binding Protein 1b of Escherichia coli

The Journal of biological chemistry, 2008-10, Vol.283 (42), p.28464-28470

2008

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Crystal Structure of the Actinomadura R39 DD-peptidase Reveals New Domains in Penicillin-binding Proteins

The Journal of biological chemistry, 2005-09, Vol.280 (35), p.31249-31256

2005

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Crystal Structure of the Mycobacterium fortuitum Class A β-Lactamase: Structural Basis for Broad Substrate Specificity

Antimicrobial Agents and Chemotherapy, 2006-07, Vol.50 (7), p.2516-2521

2006

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Dynamic Distribution and Interaction of the Arabidopsis SRSF1 Subfamily Splicing Factors

Plant physiology (Bethesda), 2016-02, Vol.170 (2), p.1000-1013

2016

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Morphine, a potential inhibitor of myeloperoxidase activity

Biochimica et biophysica acta. General subjects, 2018-10, Vol.1862 (10), p.2236-2244

2018

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The crystal structure of the cell division amidase AmiC reveals the fold of the AMIN domain, a new peptidoglycan binding domain

Molecular microbiology, 2013-10, Vol.90 (2), p.267-277

2013

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Impact of Mutations at Arg220 and Thr237 in PER-2 β-Lactamase on Conformation, Activity, and Susceptibility to Inhibitors

Antimicrobial agents and chemotherapy, 2017-06, Vol.61 (6)

2017

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Current Challenges in Antimicrobial Chemotherapy: Focus on β-Lactamase Inhibition

Drugs (New York, N.Y.), 2010-04, Vol.70 (6), p.651-679

2010

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α‐Unsaturated 3‐Amino‐1‐carboxymethyl‐β‐lactams as Bacterial PBP Inhibitors: Synthesis and Biochemical Assessment

Chemistry : a European journal, 2019-12, Vol.25 (70), p.16128-16140

2019

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In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3‐Amino‐1‐carboxymethyl‐β‐lactams as Inhibitors of Penicillin‐Binding Proteins of Resistant Bacteria

Chemistry : a European journal, 2018-10, Vol.24 (57), p.15254-15266

2018

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Biochemical and structural characterization of a mannose binding jacalin-related lectin with two-sugar binding sites from pineapple (Ananas comosus) stem

Scientific reports, 2018-07, Vol.8 (1), p.11508-14, Article 11508

2018

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PBP5 Complementation of a PBP3 Deficiency in Enterococcus hirae

Journal of Bacteriology, 2006-09, Vol.188 (17), p.6298-6307

2006

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Peptidoglycan glycosyltransferase substrate mimics as templates for the design of new antibacterial drugs

Frontiers in immunology, 2013-01, Vol.4, p.78-78

2013

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Dynamic Distribution and Interaction of the Arabidopsis SRSF1 Subfamily Splicing Factors1

Plant physiology (Bethesda), 2015-12, Vol.170 (2), p.1000-1013

2015

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Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis

Cellular and molecular life sciences : CMLS, 2017-06, Vol.74 (12), p.2319-2332

2017

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Was the Last Bacterial Common Ancestor a Monoderm after All?

Genes, 2022-02, Vol.13 (2), p.376

2022

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Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials

penicillin-binding proteins: structure and role in peptidoglycan biosynthesis

Understanding the Significance and Implications of Antibody Numbering and Antigen-Binding Surface/Residue Definition

Crystal structure of penicillin-binding protein 3 (PBP3) from Escherichia coli

Development of new drugs for an old target: the penicillin binding proteins

Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization

From "An Enzyme Able to Destroy Penicillin" to Carbapenemases: 70 Years of Beta-lactamase Misbehaviour

Crystal structure and kinetic analysis of the class B3 di-zinc metallo-β-lactamase LRA-12 from an Alaskan soil metagenome

A Lysine Cluster in Domain II of Bacillus subtilis PBP4a Plays a Role in the Membrane Attachment of This C1-PBP

Importance of the Conserved Residues in the Peptidoglycan Glycosyltransferase Module of the Class A Penicillin-binding Protein 1b of Escherichia coli

Crystal Structure of the Actinomadura R39 DD-peptidase Reveals New Domains in Penicillin-binding Proteins

Crystal Structure of the Mycobacterium fortuitum Class A β-Lactamase: Structural Basis for Broad Substrate Specificity

Dynamic Distribution and Interaction of the Arabidopsis SRSF1 Subfamily Splicing Factors

Morphine, a potential inhibitor of myeloperoxidase activity

The crystal structure of the cell division amidase AmiC reveals the fold of the AMIN domain, a new peptidoglycan binding domain

Impact of Mutations at Arg220 and Thr237 in PER-2 β-Lactamase on Conformation, Activity, and Susceptibility to Inhibitors

Current Challenges in Antimicrobial Chemotherapy: Focus on β-Lactamase Inhibition

α‐Unsaturated 3‐Amino‐1‐carboxymethyl‐β‐lactams as Bacterial PBP Inhibitors: Synthesis and Biochemical Assessment

In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3‐Amino‐1‐carboxymethyl‐β‐lactams as Inhibitors of Penicillin‐Binding Proteins of Resistant Bacteria

Biochemical and structural characterization of a mannose binding jacalin-related lectin with two-sugar binding sites from pineapple (Ananas comosus) stem

PBP5 Complementation of a PBP3 Deficiency in Enterococcus hirae

Peptidoglycan glycosyltransferase substrate mimics as templates for the design of new antibacterial drugs

Dynamic Distribution and Interaction of the Arabidopsis SRSF1 Subfamily Splicing Factors1

Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis

Was the Last Bacterial Common Ancestor a Monoderm after All?

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