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A comparison of the chemical properties of drugs and FEMA/FDA notified GRAS chemical compounds used in the food industry

Food and chemical toxicology, 2007-08, Vol.45 (8), p.1419-1427

2007

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Structural Origins of High-Affinity Biotin Binding to Streptavidin

Science (American Association for the Advancement of Science), 1989-01, Vol.243 (4887), p.85-88

1989

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Crystallographic and thermodynamic comparison of natural and synthetic ligands bound to streptavidin

Journal of the American Chemical Society, 1992-04, Vol.114 (9), p.3197-3200

1992

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High-density miniaturized thermal shift assays as a general strategy for drug discovery

Journal of biomolecular screening, 2001-12, Vol.6 (6), p.429

2001

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Amidinohydrazones as guanidine bioisosteres : Application to a new class of potent, selective and orally bioavailable, non-amide-based small-molecule thrombin inhibitors

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (1), p.1-4

2000

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The use of an imaging proportional counter in macromolecular crystallography

Journal of applied crystallography, 1987-10, Vol.20 (5), p.383-387

1987

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Molecular dynamics of a cytochrome c-cytochrome b5 electron transfer complex

Science (American Association for the Advancement of Science), 1987-11, Vol.238 (4828), p.794-797

1987

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Molecular Dynamics Simulation of a Phospholipid Micelle

Science (American Association for the Advancement of Science), 1989-02, Vol.243 (4891), p.636-638

1989

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Structural properties of protein β-sheets

Progress in biophysics and molecular biology, 1983, Vol.42 (2-3), p.95-133

Salemme, F.R.

1983

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In vitro evaluation and crystallographic analysis of a new class of selective, non-amide-based thrombin inhibitors

Bioorganic & medicinal chemistry letters, 1998-07, Vol.8 (13), p.1595-1600

1998

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Structure-activity and crystallographic analysis of a new class of non-amide-based thrombin inhibitor

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (1), p.79-82

2000

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Non-peptidic phenyl-based thrombin inhibitors : Exploring structural requirements of the S1 specificity pocket with amidines

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (1), p.83-85

2000

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Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin

Journal of the American Chemical Society, 1994-04, Vol.116 (7), p.2717-2724

1994

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Protein Crystal Growth in Microgravity

Science (American Association for the Advancement of Science), 1989-11, Vol.246 (4930), p.651-654

1989

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Structural and functional diversity in 4-α-helical proteins

Nature (London), 1980-09, Vol.287 (5777), p.82-84

1980

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Structure of ferricytochrome c′ from Rhodospirillum molischianum at 1.67 Å resolution

Journal of molecular biology, 1985-12, Vol.186 (3), p.627-643

1985

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Thermodynamic Stability of Carbonic Anhydrase: Measurements of Binding Affinity and Stoichiometry Using ThermoFluor

Biochemistry (Easton), 2005-04, Vol.44 (13), p.5258-5266

2005

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A molecular dynamics investigation of the elastomeric restoring force in elastin

Biopolymers, 1990-10, Vol.29 (12-13), p.1613-1631

1990

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Structure and Function of Cytochromes C

Annual review of biochemistry, 1977-01, Vol.46 (1), p.299-330

Salemme, F. R

1977

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Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discovery

Structure, 1997-03, Vol.5 (3), p.319-324

1997

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Electrostatic orientation during electron transfer between flavodoxin and cytochrome c

Nature (London), 1983-01, Vol.301 (5896), p.169-171

1983

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Competitor analogs for defined T cell antigens: Peptides incorporating a putative binding motif and polyproline or polyglycine spacers

Cell, 1990-01, Vol.60 (1), p.63-72

1990

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α -helix Dipole Model and Electrostatic Stabilization of 4-α -helical Proteins

Proceedings of the National Academy of Sciences - PNAS, 1982-08, Vol.79 (15), p.4545-4549

1982

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Permuteins of interleukin 1β—a simplified approach for the construction of permutated proteins having new termini

Protein engineering, 1992-07, Vol.5 (5), p.427-431

1992

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Applications of calorimetric methods to drug discovery and the study of protein interactions

Current opinion in structural biology, 2003-02, Vol.13 (1), p.115-121

2003

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A comparison of the chemical properties of drugs and FEMA/FDA notified GRAS chemical compounds used in the food industry

Structural Origins of High-Affinity Biotin Binding to Streptavidin

Crystallographic and thermodynamic comparison of natural and synthetic ligands bound to streptavidin

High-density miniaturized thermal shift assays as a general strategy for drug discovery

Amidinohydrazones as guanidine bioisosteres : Application to a new class of potent, selective and orally bioavailable, non-amide-based small-molecule thrombin inhibitors

The use of an imaging proportional counter in macromolecular crystallography

Molecular dynamics of a cytochrome c-cytochrome b5 electron transfer complex

Molecular Dynamics Simulation of a Phospholipid Micelle

Structural properties of protein β-sheets

In vitro evaluation and crystallographic analysis of a new class of selective, non-amide-based thrombin inhibitors

Structure-activity and crystallographic analysis of a new class of non-amide-based thrombin inhibitor

Non-peptidic phenyl-based thrombin inhibitors : Exploring structural requirements of the S1 specificity pocket with amidines

Structure-Based Design of Synthetic Azobenzene Ligands for Streptavidin

Protein Crystal Growth in Microgravity

Structural and functional diversity in 4-α-helical proteins

Structure of ferricytochrome c′ from Rhodospirillum molischianum at 1.67 Å resolution

Thermodynamic Stability of Carbonic Anhydrase: Measurements of Binding Affinity and Stoichiometry Using ThermoFluor

A molecular dynamics investigation of the elastomeric restoring force in elastin

Structure and Function of Cytochromes C

Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discovery

Electrostatic orientation during electron transfer between flavodoxin and cytochrome c

Competitor analogs for defined T cell antigens: Peptides incorporating a putative binding motif and polyproline or polyglycine spacers

α -helix Dipole Model and Electrostatic Stabilization of 4-α -helical Proteins

Permuteins of interleukin 1β—a simplified approach for the construction of permutated proteins having new termini

Applications of calorimetric methods to drug discovery and the study of protein interactions

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