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IRL 2500: A potent ETB selective endothelin antagonist

Bioorganic & medicinal chemistry letters, 1996-10, Vol.6 (19), p.2323-2328

1996

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Catalytic Enantioselective Hydrosilylation of Aromatic Ketones Using Rhodium Complexes of TADDOL-Derived Cyclic Phosphonites and Phosphites

Helvetica chimica acta, 1993-11, Vol.76 (7), p.2654-2665

1993

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1,3-dioxin-4-ones as versatile intermediates for organic synthesis

Journal of heterocyclic chemistry, 1990-01, Vol.27 (1), p.25-30

1990

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Highly enantioselective reduction of acetoacetylated meldrum's acid with fermenting baker's yeast

Tetrahedron letters, 1990, Vol.31 (51), p.7463-7466

1990

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Effect of prior administration of succinylcholine on duration of action of vecuronium during enflurane anaesthesia

Acta anaesthesiologica Scandinavica, 1994-05, Vol.38 (4), p.380-383

1994

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Derivatives of α,α,α′,α′-Tetraaryl-2,2-dimethyl-1,3-dioxolan-4,5-dimethanol (TADDOL) containing nitrogen, sulfur, and phosphorus atoms. New ligands and auxiliaries for enantioselective reactions

Tetrahedron, 1993-02, Vol.49 (9), p.1711-1724

1993

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Prostaglandin E1 (PGE1) prevents the pressure responses to tracheal intubation in hypertensive patients

Masui. The Japanese journal of anesthesiology, 1991-11, Vol.40 (11), p.1641

1991

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Studies on Amino Acid Derivatives. VI: Reaction of Methoxymethylene Meldrum's Acid with Amino Acid Derivatives

YAKUGAKU ZASSHI, 1986/02/25, Vol.106(2), pp.154-157

1986

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Stereoselective synthesis of a novel and bifunctional endothelin antagonist, IRL 3630

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2247-2252

1998

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Effect of a novel bifunctional endothelin receptor antagonist, IRL 3630A, on guinea pig respiratory mechanics

European journal of pharmacology, 2000-10, Vol.406 (1), p.139-147

2000

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A SHORT SYNTHESIS OF 7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE. A BASIC SKELETON OF PENICILLIN-TYPE β-LACTAMS

Chemistry letters, 1985-05, Vol.14 (5), p.659-660

1985

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Discovery of IRL 3461 : A novel and potent endothelin antagonist with balanced ETA/ETB affinity

Bioorganic & medicinal chemistry letters, 1998-08, Vol.8 (16), p.2241-2246

1998

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A case of pulmonary fat embolism and cardiac arrest after prosthetic replacement of the femoral stem

Masui. The Japanese journal of anesthesiology, 1999-04, Vol.48 (4), p.416

1999

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Derivatives of α,α,α',α'-tetraaryl-2,2-dimethyl-1,3-dioxolan-4,5-dimethanol (TADDOL) containing nitrogen, sulfur, and phosphorus atoms. New ligands and auxiliaries for enantioselective reactions: Synthesis of optically active compounds - prospects for the 21 st century

Tetrahedron, 1993, Vol.49 (9), p.1711-1724

1993

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Lipase-catalyzed asymmetric synthesis of 6-(3-chloro-2-hydroxypropyl)-1,3-dioxin-4-ones and their conversion to chiral 5,6-epoxyhexanoates

Tetrahedron: asymmetry, 1991, Vol.2 (5), p.343-346

1991

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Profiling of trans-azetidine-2,4-dicarboxylic acid at the human metabotropic glutamate receptors mGlu1b, -2, -4a and -5a

European journal of pharmacology, 1995-02, Vol.288 (3), p.389-392

1995

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Synthesis of 1,3-dioxin-4-ones having chiral hydroyalkyl groups at the 6-position by means of baker's yeast reduction and their uses for EPC synthesis

Tetrahedron, 1991, Vol.47 (32), p.6197-6214

1991

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IRL 2500: A potent ET B selective endothelin antagonist

Bioorganic & medicinal chemistry letters, 1996, Vol.6 (19), p.2323-2328

1996

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Two lactone formation reactions from 1,3-dioxin-4-ones having hydroxy-alkyl group at the 6-position : difference in ring opening and closure

Tetrahedron, 1991, Vol.47 (30), p.5689-5708

1991

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Studies on Amino Acid Derivatives. IX. : Synthesis of Chiral Penam-3-carboxylic Acid and Its Substituted Derivatives

Chemical and Pharmaceutical Bulletin, 1989/04/25, Vol.37(4), pp.877-882

1989

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REDUCTION OF OXIMES OF α-SUBSTITUTED β-KETOESTERS WITH SODIUM CYANOBOROHYDRIDE : STEREOSELECTIVE SYNTHESIS OF 3, 4-CIS-SUBSTITUTED AZETIDIN-2-ONES

Chemical and Pharmaceutical Bulletin, 1987/11/25, Vol.35(11), pp.4672-4675

1987

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A Novel Synthesis of β-Ketothioesters

Chemical and Pharmaceutical Bulletin, 1990/08/25, Vol.38(8), pp.2262-2264

1990

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A SIMPLE METHOD FOR SYNTHESIZING 7-OXO-4-THIA-1-AZABICYCLO [3. 2. 0]-HEPTANE AND ITS 6-METHYL DERIVATIVES FROM ETHYL CYANOACETATE

Chemical and Pharmaceutical Bulletin, 1985/07/25, Vol.33(7), pp.3046-3049

1985

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Synthesis of 1, 3-Dioxin-4-ones and Their Use in Synthesis. XVIII. : Synthesis of Azetidin-2-ones from 1, 3-Dioxin-4-ones via 3-Hydroxycarboxamides

Chemical and Pharmaceutical Bulletin, 1989/11/25, Vol.37(11), pp.2952-2960

1989

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ChemInform Abstract: Catalytic Enantioselective Hydrosilylation of Aromatic Ketones Using Rhodium Complexes of TADDOL-Derived Cyclic Phosphonites and Phosphites

ChemInform, 1994-03, Vol.25 (11), p.no-no

1994

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IRL 2500: A potent ETB selective endothelin antagonist

Catalytic Enantioselective Hydrosilylation of Aromatic Ketones Using Rhodium Complexes of TADDOL-Derived Cyclic Phosphonites and Phosphites

1,3-dioxin-4-ones as versatile intermediates for organic synthesis

Highly enantioselective reduction of acetoacetylated meldrum's acid with fermenting baker's yeast

Effect of prior administration of succinylcholine on duration of action of vecuronium during enflurane anaesthesia

Derivatives of α,α,α′,α′-Tetraaryl-2,2-dimethyl-1,3-dioxolan-4,5-dimethanol (TADDOL) containing nitrogen, sulfur, and phosphorus atoms. New ligands and auxiliaries for enantioselective reactions

Prostaglandin E1 (PGE1) prevents the pressure responses to tracheal intubation in hypertensive patients

Studies on Amino Acid Derivatives. VI: Reaction of Methoxymethylene Meldrum's Acid with Amino Acid Derivatives

Stereoselective synthesis of a novel and bifunctional endothelin antagonist, IRL 3630

Effect of a novel bifunctional endothelin receptor antagonist, IRL 3630A, on guinea pig respiratory mechanics

A SHORT SYNTHESIS OF 7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE. A BASIC SKELETON OF PENICILLIN-TYPE β-LACTAMS

Discovery of IRL 3461 : A novel and potent endothelin antagonist with balanced ETA/ETB affinity

A case of pulmonary fat embolism and cardiac arrest after prosthetic replacement of the femoral stem

Derivatives of α,α,α',α'-tetraaryl-2,2-dimethyl-1,3-dioxolan-4,5-dimethanol (TADDOL) containing nitrogen, sulfur, and phosphorus atoms. New ligands and auxiliaries for enantioselective reactions: Synthesis of optically active compounds - prospects for the 21 st century

Lipase-catalyzed asymmetric synthesis of 6-(3-chloro-2-hydroxypropyl)-1,3-dioxin-4-ones and their conversion to chiral 5,6-epoxyhexanoates

Profiling of trans-azetidine-2,4-dicarboxylic acid at the human metabotropic glutamate receptors mGlu1b, -2, -4a and -5a

Synthesis of 1,3-dioxin-4-ones having chiral hydroyalkyl groups at the 6-position by means of baker's yeast reduction and their uses for EPC synthesis

IRL 2500: A potent ET B selective endothelin antagonist

Two lactone formation reactions from 1,3-dioxin-4-ones having hydroxy-alkyl group at the 6-position : difference in ring opening and closure

Studies on Amino Acid Derivatives. IX. : Synthesis of Chiral Penam-3-carboxylic Acid and Its Substituted Derivatives

REDUCTION OF OXIMES OF α-SUBSTITUTED β-KETOESTERS WITH SODIUM CYANOBOROHYDRIDE : STEREOSELECTIVE SYNTHESIS OF 3, 4-CIS-SUBSTITUTED AZETIDIN-2-ONES

A Novel Synthesis of β-Ketothioesters

A SIMPLE METHOD FOR SYNTHESIZING 7-OXO-4-THIA-1-AZABICYCLO [3. 2. 0]-HEPTANE AND ITS 6-METHYL DERIVATIVES FROM ETHYL CYANOACETATE

Synthesis of 1, 3-Dioxin-4-ones and Their Use in Synthesis. XVIII. : Synthesis of Azetidin-2-ones from 1, 3-Dioxin-4-ones via 3-Hydroxycarboxamides

ChemInform Abstract: Catalytic Enantioselective Hydrosilylation of Aromatic Ketones Using Rhodium Complexes of TADDOL-Derived Cyclic Phosphonites and Phosphites

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