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ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models

Molecules (Basel, Switzerland), 2020-09, Vol.25 (19), p.4499

2020

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An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression

Cell, 2012-12, Vol.151 (7), p.1474-1487

2012

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A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells

Scientific reports, 2016-10, Vol.6 (1), p.34653-34653, Article 34653

2016

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A Coumarin-Imidazothiadiazole Derivative, SP11 Abrogates Tumor Growth by Targeting HSP90 and Its Client Proteins

Molecules (Basel, Switzerland), 2023-07, Vol.28 (13), p.5226

2023

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Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice

PloS one, 2012-09, Vol.7 (9), p.e43632

2012

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Curcumin derivative 1, 2-bis [(3E, 5E)-3, 5-bis [(2-chlorophenyl) methylene]-4-oxo-1-piperidyl] ethane-1, 2-dione (ST03) induces mitochondria mediated apoptosis in ovarian cancer cells and inhibits tumor progression in EAC mouse model

Translational oncology, 2022-01, Vol.15 (1), p.101280, Article 101280

2022

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Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms

Pharmacological reports, 2022-02, Vol.74 (1), p.159-174

2022

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Enhanced Efficacy of Pluronic Copolymer Micelle Encapsulated SCR7 against Cancer Cell Proliferation

Macromolecular bioscience, 2015-04, Vol.15 (4), p.521-534

2015

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Synthesis, characterization, and biological evaluation of some 4-((thiophen-2-yl-methylene)amino)benzenesulfonamide metal complexes

Beni-Suef University journal of basic and applied sciences, 2021-12, Vol.10 (1), p.28-9, Article 28

2021

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Pluronic copolymer encapsulated SCR7 as a potential anticancer agent

Faraday discussions, 2015-01, Vol.177, p.155-161

2015

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Synthesis, in silico ADME, molecular docking and in vitro cytotoxicity evaluation of stilbene linked 1,2,3-triazoles

Heliyon, 2021-01, Vol.7 (1), p.e05893-e05893, Article e05893

2021

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Synthesis, Anticancer Evaluation and Molecular Docking of Hexahydroquinoline Derivatives as Mcl-1 Inhibitors and Apoptosis Inducers

Anti-cancer agents in medicinal chemistry, 2022-01, Vol.22 (11), p.2142-2155

2022

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Synthesis, Cytotoxicity Evaluation and Molecular Docking of Fluorine Containing Hexahydroquinoline-3-Carbonitrile Derivatives

Current drug discovery technologies, 2022, Vol.19 (1), p.e140122189603

2022

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Investigation of anti-cancer and migrastatic properties of novel curcumin derivatives on breast and ovarian cancer cell lines

BMC complementary and alternative medicine, 2019-10, Vol.19 (1), p.273, Article 273

2019

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Effects of green synthesised silver nanoparticles (ST06-AgNPs) using curcumin derivative (ST06) on human cervical cancer cells (HeLa) in vitro and EAC tumor bearing mice models

International journal of nanomedicine, 2019-01, Vol.14, p.5257-5270

2019

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Microwave Assisted Synthesis, Characterization of Some New Isatin and Thiophene Derivatives as Cytotoxic and Chemopreventive Agents

Letters in drug design & discovery, 2012-12, Vol.9 (10), p.934-941

2012

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Synthesis of Novel Pyrazole-Oxindole Conjugates with Cytotoxicity in Human Cancer Cells via Apoptosis

Chemistry & biodiversity, 2023-09, Vol.20 (9), p.e202300843-e202300843

2023

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Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives

Computational biology and chemistry, 2022-04, Vol.97, p.107641-107641, Article 107641

2022

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Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner

The FEBS journal, 2018-11, Vol.285 (21), p.3959-3976

2018

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Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4′-fluorophenyl)-imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent anticancer agents

European journal of medicinal chemistry, 2011-06, Vol.46 (6), p.2109-2116

2011

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Novel BCL2 inhibitor, Disarib induces apoptosis by disruption of BCL2-BAK interaction

Biochemical pharmacology, 2017-05, Vol.131, p.16-28

2017

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3,5-Bis(3-dimethylaminomethyl-4-hydroxybenzylidene)-4-piperidone and related compounds induce glutathione oxidation and mitochondria-mediated cell death in HCT-116 colon cancer cells

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (16), p.3669-3673

2017

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A novel inhibitor of BCL2, Disarib abrogates tumor growth while sparing platelets, by activating intrinsic pathway of apoptosis

Biochemical pharmacology, 2016-12, Vol.122, p.10-22

2016

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Identification of a novel BCL2‐specific inhibitor that binds predominantly to the BH1 domain

The FEBS journal, 2016-09, Vol.283 (18), p.3408-3437

2016

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Identification and characterization of novel ligase I inhibitors

Molecular carcinogenesis, 2017-02, Vol.56 (2), p.550-566

2017

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ST09, A Novel Curcumin Derivative, Blocks Cell Migration by Inhibiting Matrix Metalloproteases in Breast Cancer Cells and Inhibits Tumor Progression in EAC Mouse Tumor Models

An Inhibitor of Nonhomologous End-Joining Abrogates Double-Strand Break Repair and Impedes Cancer Progression

A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells

A Coumarin-Imidazothiadiazole Derivative, SP11 Abrogates Tumor Growth by Targeting HSP90 and Its Client Proteins

Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice

Curcumin derivative 1, 2-bis [(3E, 5E)-3, 5-bis [(2-chlorophenyl) methylene]-4-oxo-1-piperidyl] ethane-1, 2-dione (ST03) induces mitochondria mediated apoptosis in ovarian cancer cells and inhibits tumor progression in EAC mouse model

Three novel piperidones exhibit tumor-selective cytotoxicity on leukemia cells via protein degradation and stress-mediated mechanisms

Enhanced Efficacy of Pluronic Copolymer Micelle Encapsulated SCR7 against Cancer Cell Proliferation

Synthesis, characterization, and biological evaluation of some 4-((thiophen-2-yl-methylene)amino)benzenesulfonamide metal complexes

Pluronic copolymer encapsulated SCR7 as a potential anticancer agent

Synthesis, in silico ADME, molecular docking and in vitro cytotoxicity evaluation of stilbene linked 1,2,3-triazoles

Synthesis, Anticancer Evaluation and Molecular Docking of Hexahydroquinoline Derivatives as Mcl-1 Inhibitors and Apoptosis Inducers

Synthesis, Cytotoxicity Evaluation and Molecular Docking of Fluorine Containing Hexahydroquinoline-3-Carbonitrile Derivatives

Investigation of anti-cancer and migrastatic properties of novel curcumin derivatives on breast and ovarian cancer cell lines

Effects of green synthesised silver nanoparticles (ST06-AgNPs) using curcumin derivative (ST06) on human cervical cancer cells (HeLa) in vitro and EAC tumor bearing mice models

Microwave Assisted Synthesis, Characterization of Some New Isatin and Thiophene Derivatives as Cytotoxic and Chemopreventive Agents

Synthesis of Novel Pyrazole-Oxindole Conjugates with Cytotoxicity in Human Cancer Cells via Apoptosis

Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives

Autocyclized and oxidized forms of SCR7 induce cancer cell death by inhibiting nonhomologous DNA end joining in a Ligase IV dependent manner

Synthesis and biological evaluation of novel 2-aralkyl-5-substituted-6-(4′-fluorophenyl)-imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent anticancer agents

Novel BCL2 inhibitor, Disarib induces apoptosis by disruption of BCL2-BAK interaction

3,5-Bis(3-dimethylaminomethyl-4-hydroxybenzylidene)-4-piperidone and related compounds induce glutathione oxidation and mitochondria-mediated cell death in HCT-116 colon cancer cells

A novel inhibitor of BCL2, Disarib abrogates tumor growth while sparing platelets, by activating intrinsic pathway of apoptosis

Identification of a novel BCL2‐specific inhibitor that binds predominantly to the BH1 domain

Identification and characterization of novel ligase I inhibitors

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