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Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (43), p.17644-17648

2011

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Structures of Mismatch Replication Errors Observed in a DNA Polymerase

Cell, 2004-03, Vol.116 (6), p.803-816

2004

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Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

Proceedings of the National Academy of Sciences - PNAS, 2017-06, Vol.114 (23), p.6010-6015

2017

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Structure of the Human MutSα DNA Lesion Recognition Complex

Molecular cell, 2007-05, Vol.26 (4), p.579-592

2007

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Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

Cell, 2011-04, Vol.145 (2), p.212-223

2011

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Processive DNA Synthesis Observed in a Polymerase Crystal Suggests a Mechanism for the Prevention of Frameshift Mutations

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (7), p.3895-3900

2003

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Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

Nature, 2004-09, Vol.431 (7005), p.217-221

2004

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Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5324

2024

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Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway

Cell reports (Cambridge), 2017-10, Vol.21 (5), p.1375-1385

2017

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Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

Nature (London), 1998-01, Vol.391 (6664), p.304-307

1998

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Crystal Structure of Protein Farnesyltransferase at 2.25 Angstrom Resolution

Science (American Association for the Advancement of Science), 1997-03, Vol.275 (5307), p.1800-1804

1997

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Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching

Communications chemistry, 2023-08, Vol.6 (1), p.168-12, Article 168

2023

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The Closing Mechanism of DNA Polymerase I at Atomic Resolution

Structure (London), 2015-09, Vol.23 (9), p.1609-1620

2015

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Reaction path of protein farnesyltransferase at atomic resolution

Nature (London), 2002-10, Vol.419 (6907), p.645-650

2002

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The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis

Structure (London), 2010-01, Vol.18 (1), p.83-93

2010

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Thermally controlled intein splicing of engineered DNA polymerases provides a robust and generalizable solution for accurate and sensitive molecular diagnostics

Nucleic acids research, 2023-06, Vol.51 (11), p.5883-5894

2023

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Crystallographic Analysis of CaaX Prenyltransferases Complexed with Substrates Defines Rules of Protein Substrate Selectivity

Journal of molecular biology, 2004-10, Vol.343 (2), p.417-433

2004

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Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold

The Journal of biological chemistry, 2009-11, Vol.284 (48), p.33217-33223

2009

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Structure of Protein Geranylgeranyltransferase-I from the Human Pathogen Candida albicans Complexed with a Lipid Substrate

The Journal of biological chemistry, 2008-11, Vol.283 (46), p.31933-31940

2008

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Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication

Journal of molecular biology, 2005-02, Vol.280 (5), p.3764-3770

2005

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Accurate Identification of Periplasmic Urea-binding Proteins by Structure- and Genome Context-assisted Functional Analysis

Journal of molecular biology, 2024-11, Vol.436 (22), p.168780, Article 168780

2024

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Using consensus methods to develop a Social Prescribing Learning Needs Framework for practitioners in Wales

Perspectives in Public Health, 2021-05, Vol.141 (3), p.136-148

2021

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Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA

Science (American Association for the Advancement of Science), 1993-04, Vol.260 (5106), p.352-355

1993

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The Crystal Structure of Human Protein Farnesyltransferase Reveals the Basis for Inhibition by CaaX Tetrapeptides and Their Mimetics

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (23), p.12948-12953

2001

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The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

The Journal of biological chemistry, 2011-06, Vol.286 (22), p.19758-19767

2011

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Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

Structures of Mismatch Replication Errors Observed in a DNA Polymerase

Interplay of catalysis, fidelity, threading, and processivity in the exo- and endonucleolytic reactions of human exonuclease I

Structure of the Human MutSα DNA Lesion Recognition Complex

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

Processive DNA Synthesis Observed in a Polymerase Crystal Suggests a Mechanism for the Prevention of Frameshift Mutations

Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase

Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase

Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway

Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

Crystal Structure of Protein Farnesyltransferase at 2.25 Angstrom Resolution

Chromophore carbonyl twisting in fluorescent biosensors encodes direct readout of protein conformations with multicolor switching

The Closing Mechanism of DNA Polymerase I at Atomic Resolution

Reaction path of protein farnesyltransferase at atomic resolution

The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis

Thermally controlled intein splicing of engineered DNA polymerases provides a robust and generalizable solution for accurate and sensitive molecular diagnostics

Crystallographic Analysis of CaaX Prenyltransferases Complexed with Substrates Defines Rules of Protein Substrate Selectivity

Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold

Structure of Protein Geranylgeranyltransferase-I from the Human Pathogen Candida albicans Complexed with a Lipid Substrate

Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication

Accurate Identification of Periplasmic Urea-binding Proteins by Structure- and Genome Context-assisted Functional Analysis

Using consensus methods to develop a Social Prescribing Learning Needs Framework for practitioners in Wales

Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA

The Crystal Structure of Human Protein Farnesyltransferase Reveals the Basis for Inhibition by CaaX Tetrapeptides and Their Mimetics

The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

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