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Ethanol's molecular targets

Science signaling, 2008-07, Vol.1 (28), p.re7

2008

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An intersubunit electrostatic interaction in the GABAA receptor facilitates its responses to benzodiazepines

The Journal of biological chemistry, 2018-05, Vol.293 (21), p.8264-8274

2018

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Disruption of a putative intersubunit electrostatic bond enhances agonist efficacy at the human α1 glycine receptor

Brain research, 2017-02, Vol.1657, p.148-155

2017

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Trifluoroacetate is an allosteric modulator with selective actions at the glycine receptor

Neuropharmacology, 2012-09, Vol.63 (3), p.368-373

2012

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Sites of alcohol and volatile anaesthetic action on GABA A and glycine receptors

Nature (London), 1997-09, Vol.389 (6649), p.385-389

1997

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Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols

The Journal of pharmacology and experimental therapeutics, 2012-02, Vol.340 (2), p.304-316

2012

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Single-channel analysis of ethanol enhancement of glycine receptor function

The Journal of pharmacology and experimental therapeutics, 2009-07, Vol.330 (1), p.198-205

2009

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Single Channel Analysis of Isoflurane and Ethanol Enhancement of Taurine-Activated Glycine Receptors

The Journal of pharmacology and experimental therapeutics, 2018-01, Vol.364 (1), p.70-76

2018

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Ketone body modulation of ligand-gated ion channels

Neuropharmacology, 2019-04, Vol.148, p.21-30

2019

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Disruption of an intersubunit electrostatic bond is a critical step in glycine receptor activation

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (17), p.7987-7992

2010

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Mutations of γ -aminobutyric Acid and Glycine Receptors Change Alcohol Cutoff: Evidence for an Alcohol Receptor?

Proceedings of the National Academy of Sciences - PNAS, 1998-05, Vol.95 (11), p.6504-6509

1998

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Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice

Anesthesiology (Philadelphia), 2012-10, Vol.117 (4), p.765-771

2012

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F654A and K558Q Mutations in NMDA Receptor 1 Affect Ethanol‐Induced Behaviors in Drosophila

Alcoholism, clinical and experimental research, 2019-12, Vol.43 (12), p.2480-2493

2019

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Interactions between Zinc and Allosteric Modulators of the Glycine Receptor

The Journal of pharmacology and experimental therapeutics, 2017-04, Vol.361 (1), p.1-8

2017

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Allosteric modulation of the glycine receptor activated by agonists differing in efficacy

Brain research, 2015-05, Vol.1606, p.95-101

2015

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Positive allosteric modulators differentially affect full versus partial agonist activation of the glycine receptor

The Journal of pharmacology and experimental therapeutics, 2012-07, Vol.342 (1), p.61-70

2012

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Contaminating levels of zinc found in commonly-used labware and buffers affect glycine receptor currents

Brain research bulletin, 2014-01, Vol.100, p.1-5

2014

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Actions of anesthetics on ligand‐gated ion channels: role of receptor subunit composition

The FASEB journal, 1995-11, Vol.9 (14), p.1454-1462

1995

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A Novel Peptide Restricts Ethanol Modulation of the BK Channel In Vitro and In Vivo

The Journal of pharmacology and experimental therapeutics, 2018-11, Vol.367 (2), p.282-290

2018

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Occupancy of a Single Anesthetic Binding Pocket Is Sufficient to Enhance Glycine Receptor Function

The Journal of biological chemistry, 2006-02, Vol.281 (6), p.3305-3311

2006

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Physiological concentrations of zinc reduce taurine-activated GlyR responses to drugs of abuse

Neuropharmacology, 2013-12, Vol.75, p.286-294

2013

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Identification of Novel Specific Allosteric Modulators of the Glycine Receptor Using Phage Display

The Journal of biological chemistry, 2010-07, Vol.285 (30), p.22840-22845

2010

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Ethanol Enhances Taurine-Activated Glycine Receptor Function

Alcoholism, clinical and experimental research, 2010-09, Vol.34 (9), p.1634-1639

2010

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An intersubunit electrostatic interaction in the GABA A receptor facilitates its responses to benzodiazepines

The Journal of biological chemistry, 2018-05, Vol.293 (21), p.8264

2018

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Inhaled drugs of abuse enhance serotonin-3 receptor function

Drug and alcohol dependence, 2003-05, Vol.70 (1), p.11-15

2003

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Ethanol's molecular targets

An intersubunit electrostatic interaction in the GABAA receptor facilitates its responses to benzodiazepines

Disruption of a putative intersubunit electrostatic bond enhances agonist efficacy at the human α1 glycine receptor

Trifluoroacetate is an allosteric modulator with selective actions at the glycine receptor

Sites of alcohol and volatile anaesthetic action on GABA A and glycine receptors

Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols

Single-channel analysis of ethanol enhancement of glycine receptor function

Single Channel Analysis of Isoflurane and Ethanol Enhancement of Taurine-Activated Glycine Receptors

Ketone body modulation of ligand-gated ion channels

Disruption of an intersubunit electrostatic bond is a critical step in glycine receptor activation

Mutations of γ -aminobutyric Acid and Glycine Receptors Change Alcohol Cutoff: Evidence for an Alcohol Receptor?

Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice

F654A and K558Q Mutations in NMDA Receptor 1 Affect Ethanol‐Induced Behaviors in Drosophila

Interactions between Zinc and Allosteric Modulators of the Glycine Receptor

Allosteric modulation of the glycine receptor activated by agonists differing in efficacy

Positive allosteric modulators differentially affect full versus partial agonist activation of the glycine receptor

Contaminating levels of zinc found in commonly-used labware and buffers affect glycine receptor currents

Actions of anesthetics on ligand‐gated ion channels: role of receptor subunit composition

A Novel Peptide Restricts Ethanol Modulation of the BK Channel In Vitro and In Vivo

Occupancy of a Single Anesthetic Binding Pocket Is Sufficient to Enhance Glycine Receptor Function

Physiological concentrations of zinc reduce taurine-activated GlyR responses to drugs of abuse

Identification of Novel Specific Allosteric Modulators of the Glycine Receptor Using Phage Display

Ethanol Enhances Taurine-Activated Glycine Receptor Function

An intersubunit electrostatic interaction in the GABA A receptor facilitates its responses to benzodiazepines

Inhaled drugs of abuse enhance serotonin-3 receptor function

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