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Structural biology of the purine biosynthetic pathway

Cellular and molecular life sciences : CMLS, 2008-11, Vol.65 (23), p.3699-3724

2008

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Crystal structure of human intrinsic factor: Cobalamin complex at 2.6-Å resolution

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (44), p.17311-17316

2007

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Postcrystallization Analysis of the Irreproducibility of the Human Intrinsic Factor−Cobalamin Complex Crystals

Crystal growth & design, 2009-01, Vol.9 (1), p.348-351

2009

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Observation of an unexpected third receptor molecule in the crystal structure of human interferon-γ receptor complex

Structure (London), 2000-09, Vol.8 (9), p.927-936

2000

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Structure of a Human S-Adenosylmethionine Decarboxylase Self-Processing Ester Intermediate and Mechanism of Putrescine Stimulation of Processing As Revealed by the H243A Mutant

Biochemistry (Easton), 2001-08, Vol.40 (32), p.9495-9504

2001

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Three-Dimensional Structure of Recombinant Human Interferon-γ

Science (American Association for the Advancement of Science), 1991-05, Vol.252 (5006), p.698-702

1991

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The Structural Basis for Substrate Specificity and Inhibition of Human S-Adenosylmethionine Decarboxylase

Biochemistry (Easton), 2001-08, Vol.40 (32), p.9484-9494

2001

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The crystal structure of ADP- l-glycero- d-mannoheptose 6-epimerase: catalysis with a twist

Structure (London), 2000-05, Vol.8 (5), p.453-462

2000

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Structural Characterization of the Enzyme−Substrate, Enzyme−Intermediate, and Enzyme−Product Complexes of Thiamin Phosphate Synthase

Biochemistry (Easton), 2001-08, Vol.40 (34), p.10103-10114

2001

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Selenium-based MAD phasing: setting the sites on larger structures

Structure (London), 1999-07, Vol.7 (7), p.R161-R166

1999

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The structural basis for the remarkable catalytic proficiency of orotidine 5′-monophosphate decarboxylase

Current Opinion in Structural Biology, 2000-12, Vol.10 (6), p.711-718

2000

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Crystal structure of recombinant human interleukin-4

The Journal of biological chemistry, 1992-10, Vol.267 (28), p.20371-20376

1992

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The Crystal Structure and Mechanism of Orotidine 5′-monophosphate Decarboxylase

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (5), p.2005-2010

2000

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Investigation of the ATP Binding Site of Escherichia coli Aminoimidazole Ribonucleotide Synthetase Using Affinity Labeling and Site-Directed Mutagenesis

Biochemistry (Easton), 1999-08, Vol.38 (31), p.9831-9839

1999

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Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor

Journal of molecular biology, 1992-04, Vol.224 (4), p.1075-1085

1992

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Application of Crystallographic and Modeling Methods in the Design of Purine Nucleoside Phosphorylase Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 1991-12, Vol.88 (24), p.11540-11544

1991

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Advances in multiple wavelength anomalous diffraction crystallography

Current Opinion in Chemical Biology, 2000-10, Vol.4 (5), p.495-499

Ealick, Steven E

2000

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Synthesis and Biological Activity of Certain 4‘-Thio-d-arabinofuranosylpurine Nucleosides

Journal of medicinal chemistry, 1998-09, Vol.41 (20), p.3865-3871

1998

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Thiamin biosynthesis in prokaryotes

Archives of microbiology, 1999-04, Vol.171 (5), p.293-300

1999

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Ab Initio Structure Determination and Refinement of a Scorpion Protein Toxin

Acta crystallographica. Section D, Biological crystallography., 1997-09, Vol.53 (5), p.551-557

1997

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Modular evolution of the purine biosynthetic pathway

Current Opinion in Chemical Biology, 2000-10, Vol.4 (5), p.567-572

2000

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Purine Nucleoside Phosphorylase. 2. Catalytic Mechanism

Biochemistry (Easton), 1997-09, Vol.36 (39), p.11735-11748

1997

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Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding

Journal of molecular biology, 2000-05, Vol.298 (5), p.875-893

2000

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Calf Spleen Purine Nucleoside Phosphorylase Complexed with Substrates and Substrate Analogues

Biochemistry (Easton), 1998-05, Vol.37 (20), p.7135-7146

1998

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The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

Structure (London), 1997-10, Vol.5 (10), p.1373-1383

1997

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Structural biology of the purine biosynthetic pathway

Crystal structure of human intrinsic factor: Cobalamin complex at 2.6-Å resolution

Postcrystallization Analysis of the Irreproducibility of the Human Intrinsic Factor−Cobalamin Complex Crystals

Observation of an unexpected third receptor molecule in the crystal structure of human interferon-γ receptor complex

Structure of a Human S-Adenosylmethionine Decarboxylase Self-Processing Ester Intermediate and Mechanism of Putrescine Stimulation of Processing As Revealed by the H243A Mutant

Three-Dimensional Structure of Recombinant Human Interferon-γ

The Structural Basis for Substrate Specificity and Inhibition of Human S-Adenosylmethionine Decarboxylase

The crystal structure of ADP- l-glycero- d-mannoheptose 6-epimerase: catalysis with a twist

Structural Characterization of the Enzyme−Substrate, Enzyme−Intermediate, and Enzyme−Product Complexes of Thiamin Phosphate Synthase

Selenium-based MAD phasing: setting the sites on larger structures

The structural basis for the remarkable catalytic proficiency of orotidine 5′-monophosphate decarboxylase

Crystal structure of recombinant human interleukin-4

The Crystal Structure and Mechanism of Orotidine 5′-monophosphate Decarboxylase

Investigation of the ATP Binding Site of Escherichia coli Aminoimidazole Ribonucleotide Synthetase Using Affinity Labeling and Site-Directed Mutagenesis

Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor

Application of Crystallographic and Modeling Methods in the Design of Purine Nucleoside Phosphorylase Inhibitors

Advances in multiple wavelength anomalous diffraction crystallography

Synthesis and Biological Activity of Certain 4‘-Thio-d-arabinofuranosylpurine Nucleosides

Thiamin biosynthesis in prokaryotes

Ab Initio Structure Determination and Refinement of a Scorpion Protein Toxin

Modular evolution of the purine biosynthetic pathway

Purine Nucleoside Phosphorylase. 2. Catalytic Mechanism

Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding

Calf Spleen Purine Nucleoside Phosphorylase Complexed with Substrates and Substrate Analogues

The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology

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