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Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

PloS one, 2015-07, Vol.10 (7), p.e0132004-e0132004

2015

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Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture

Molecular therapy. Nucleic acids, 2023-09, Vol.33, p.898-907

2023

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Synthesis of 2′-modified N6-methyladenosine phosphoramidites and their incorporation into siRNA

Bioorganic & medicinal chemistry letters, 2023-02, Vol.81, p.129126-129126, Article 129126

2023

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Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis

Bioorganic & medicinal chemistry, 2012-03, Vol.20 (5), p.1699-1710

2012

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Access to 1′-Amino Carbocyclic Phosphoramidite to Enable Postsynthetic Functionalization of Oligonucleotides

Organic letters, 2021-09, Vol.23 (17), p.6735-6739

2021

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Interaction of Avibactam with Class B Metallo-β-Lactamases

Antimicrobial agents and chemotherapy, 2016-10, Vol.60 (10), p.5655-5662

2016

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Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

Nature chemistry, 2014-12, Vol.6 (12), p.1084-1090

2014

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Assay Platform for Clinically Relevant Metallo-β-lactamases

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6945-6953

2013

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Epigenetic Modification 6‐Methyladenosine Can Impact the Potency and Specificity of siRNA

Chembiochem : a European journal of chemical biology, 2021-02, Vol.22 (3), p.491-495

2021

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Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

Nature communications, 2014-03, Vol.5, p.3423-3423

2014

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mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation

Nucleic acids research, 2017-09, Vol.45 (15), p.8661-8675

2017

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F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

Chemical communications (Cambridge, England), 2019-12, Vol.55 (98), p.14717-1472

2019

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19 F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

Chemical communications (Cambridge, England), 2019-12, Vol.55 (98), p.14717-14720

2019

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Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles

Antimicrobial agents and chemotherapy, 2016-03, Vol.60 (3), p.1377-1384

2016

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Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

Nature communications, 2014-03, Vol.5 (1), Article 3423

2014

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Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for 19F NMR Studies

Journal of organic chemistry, 2015-04, Vol.80 (8), p.3982-3997

2015

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Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

Bioorganic & medicinal chemistry, 2018-07, Vol.26 (11), p.2928-2936

2018

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Use of ferrous iron by metallo-β-lactamases

Journal of inorganic biochemistry, 2016-10, Vol.163, p.185-193

2016

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Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates

Antimicrobial agents and chemotherapy, 2016-07, Vol.60 (7), p.4170-4175

2016

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Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Chemistry : a European journal, 2016-01, Vol.22 (4), p.1270-1276

2016

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Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1

Chemical science (Cambridge), 2015-01, Vol.6 (2), p.956-963

2015

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A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

Analytical biochemistry, 2012, Vol.420 (1), p.41-47

2012

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Modulating carnitine levels by targeting its biosynthesis – selective inhibition of γ-butyrobetaine hydroxylase

Chemical science (Cambridge), 2014-01, Vol.5 (5), p.1765-1771

2014

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Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture

Synthesis of 2′-modified N6-methyladenosine phosphoramidites and their incorporation into siRNA

Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis

Access to 1′-Amino Carbocyclic Phosphoramidite to Enable Postsynthetic Functionalization of Oligonucleotides

Interaction of Avibactam with Class B Metallo-β-Lactamases

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

Assay Platform for Clinically Relevant Metallo-β-lactamases

Epigenetic Modification 6‐Methyladenosine Can Impact the Potency and Specificity of siRNA

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation

F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

19 F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

Comparison of Verona Integron-Borne Metallo-β-Lactamase (VIM) Variants Reveals Differences in Stability and Inhibition Profiles

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation

Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for 19F NMR Studies

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

Use of ferrous iron by metallo-β-lactamases

Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates

Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1

A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

Modulating carnitine levels by targeting its biosynthesis – selective inhibition of γ-butyrobetaine hydroxylase

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