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Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

PloS one, 2015-07, Vol.10 (7), p.e0132004-e0132004

2015

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Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture

Molecular therapy. Nucleic acids, 2023-09, Vol.33, p.898-907

2023

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Synthesis of 2′-modified N6-methyladenosine phosphoramidites and their incorporation into siRNA

Bioorganic & medicinal chemistry letters, 2023-02, Vol.81, p.129126-129126, Article 129126

2023

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Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis

Bioorganic & medicinal chemistry, 2012-03, Vol.20 (5), p.1699-1710

2012

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Access to 1′-Amino Carbocyclic Phosphoramidite to Enable Postsynthetic Functionalization of Oligonucleotides

Organic letters, 2021-09, Vol.23 (17), p.6735-6739

2021

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Interaction of Avibactam with Class B Metallo-β-Lactamases

Antimicrobial agents and chemotherapy, 2016-10, Vol.60 (10), p.5655-5662

2016

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Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

Nature chemistry, 2014-12, Vol.6 (12), p.1084-1090

2014

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Assay Platform for Clinically Relevant Metallo-β-lactamases

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6945-6953

2013

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Epigenetic Modification 6‐Methyladenosine Can Impact the Potency and Specificity of siRNA

Chembiochem : a European journal of chemical biology, 2021-02, Vol.22 (3), p.491-495

2021

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Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

Nature communications, 2014-03, Vol.5, p.3423-3423

2014

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mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation

Nucleic acids research, 2017-09, Vol.45 (15), p.8661-8675

2017

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F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

Chemical communications (Cambridge, England), 2019-12, Vol.55 (98), p.14717-1472

2019

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19 F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

Chemical communications (Cambridge, England), 2019-12, Vol.55 (98), p.14717-14720

2019

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Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

Nature communications, 2014-03, Vol.5 (1), Article 3423

2014

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Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

Bioorganic & medicinal chemistry, 2018-07, Vol.26 (11), p.2928-2936

2018

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Use of ferrous iron by metallo-β-lactamases

Journal of inorganic biochemistry, 2016-10, Vol.163, p.185-193

2016

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Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates

Antimicrobial agents and chemotherapy, 2016-07, Vol.60 (7), p.4170-4175

2016

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Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Chemistry : a European journal, 2016-01, Vol.22 (4), p.1270-1276

2016

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Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1

Chemical science (Cambridge), 2015-01, Vol.6 (2), p.956-963

2015

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A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

Analytical biochemistry, 2012, Vol.420 (1), p.41-47

2012

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Modulating carnitine levels by targeting its biosynthesis – selective inhibition of γ-butyrobetaine hydroxylase

Chemical science (Cambridge), 2014-01, Vol.5 (5), p.1765-1771

2014

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Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications

Chemical communications (Cambridge, England), 2014-02, Vol.50 (10), p.1175-1177

2014

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Oxygenase-Catalyzed Desymmetrization of N,N-Dialkyl-piperidine-4-carboxylic Acids

Angewandte Chemie (International ed.), 2014-10, Vol.53 (41), p.10925-10927

International ed. in English, 2014

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Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture

Synthesis of 2′-modified N6-methyladenosine phosphoramidites and their incorporation into siRNA

Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety—fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis

Access to 1′-Amino Carbocyclic Phosphoramidite to Enable Postsynthetic Functionalization of Oligonucleotides

Interaction of Avibactam with Class B Metallo-β-Lactamases

Rhodanine hydrolysis leads to potent thioenolate mediated metallo-β-lactamase inhibition

Assay Platform for Clinically Relevant Metallo-β-lactamases

Epigenetic Modification 6‐Methyladenosine Can Impact the Potency and Specificity of siRNA

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

mRNA cap analogues substituted in the tetraphosphate chain with CX2: identification of O-to-CCl2 as the first bridging modification that confers resistance to decapping without impairing translation

F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

19 F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

Use of ferrous iron by metallo-β-lactamases

Sideromimic Modification of Lactivicin Dramatically Increases Potency against Extensively Drug-Resistant Stenotrophomonas maltophilia Clinical Isolates

Cation-π Interactions Contribute to Substrate Recognition in γ-Butyrobetaine Hydroxylase Catalysis

Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1

A boronic-acid-based probe for fluorescence polarization assays with penicillin binding proteins and β-lactamases

Modulating carnitine levels by targeting its biosynthesis – selective inhibition of γ-butyrobetaine hydroxylase

Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications

Oxygenase-Catalyzed Desymmetrization of N,N-Dialkyl-piperidine-4-carboxylic Acids

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