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Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models

British journal of cancer, 2014-04, Vol.110 (7), p.1733-1743

2014

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Irinotecan in the Treatment of Colorectal Cancer: Clinical Overview

Journal of clinical oncology, 2001-03, Vol.19 (5), p.1501-1518

2001

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Synergistic antitumor activity of irinotecan in combination with 5-fluorouracil in rats bearing advanced colorectal cancer : Role of drug sequence and dose

Cancer research (Chicago, Ill.), 2000-07, Vol.60 (14), p.3717-3721

2000

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Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors

Journal of clinical oncology, 1997-01, Vol.15 (1), p.389-400

1997

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Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study

Annals of oncology, 2003-09, Vol.14 (9), p.1442-1448

2003

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Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1α expression, resulting in reduced angiogenesis

Oncogene, 2006-04, Vol.25 (17), p.2509-2519

2006

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Randomized Double-Blind, Placebo-Controlled, Multicenter Phase 2 Trial of Selenomethionine as a Modulator of Efficacy and Toxicity of Chemoradiation in Locally-Advanced Squamous Cell Carcinoma of the Head and Neck

International journal of radiation oncology, biology, physics, 2013-10, Vol.87 (2), p.S466-S467

2013

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Concurrent Carboplatin, Paclitaxel, and Selenomethionine in Combination With Radiation for Patients With Unresectable Stage III Non-Small Cell Lung Cancer: A Phase 2 Multicenter Trial

International journal of radiation oncology, biology, physics, 2013-10, Vol.87 (2), p.S76-S77

2013

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Modeling of the time-dependency of in vitro drug cytotoxicity and resistance

Cancer research (Chicago, Ill.), 1998-12, Vol.58 (24), p.5749-5761

1998

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Comparative antitumor efficacy of docetaxel and paclitaxel in nude mice bearing human tumor xenografts that overexpress the multidrug resistance protein (MRP)

Annals of oncology, 1997-12, Vol.8 (12), p.1221-1228

1997

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Comparison of 5-fluoro-2′-deoxyuridine with 5-fluorouracil and their role in the treatment of colorectal cancer

European Journal of Cancer, 1998-02, Vol.34 (3), p.296-306

1998

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Phase I Study of a Weekly Schedule of Irinotecan, High-Dose Leucovorin, and Infusional Fluorouracil as First-Line Chemotherapy in Patients With Advanced Colorectal Cancer

Journal of clinical oncology, 1999-03, Vol.17 (3), p.907-913

1999

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MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors

The American journal of pathology, 1996-09, Vol.149 (3), p.853-858

1996

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A phase I study of capecitabine and a modulatory dose of irinotecan in metastatic breast cancer

Cancer chemotherapy and pharmacology, 2008-01, Vol.61 (1), p.125-131

2008

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5-Ethynyluracil (776C85) : modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma

Cancer research (Chicago, Ill.), 1994-03, Vol.54 (6), p.1507-1510

1994

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Interleukin 15 offers selective protection from irinotecan-induced intestinal toxicity in a preclinical animal model

Cancer research (Chicago, Ill.), 1998-08, Vol.58 (15), p.3270-3274

1998

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Overexpression of Bax Enhances Antitumor Activity of Chemotherapeutic Agents in Human Head and Neck Squamous Cell Carcinoma

Clinical cancer research, 2000-02, Vol.6 (2), p.718-724

2000

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d,l-buthionine-(S,R)-sulfoximine potentiates in vivo the therapeutic efficacy of doxorubicin against multidrug resistance protein-expressing tumors

Clinical cancer research, 1996-12, Vol.2 (12), p.1961-1968

1996

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S-phase modulation by irinotecan : pilot studies in advanced solid tumors

Cancer chemotherapy and pharmacology, 2005-11, Vol.56 (5), p.447-454

2005

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Results of phase I clinical trial of high doses of seleno-l-methionine (SLM) in sequential combination with axitinib in previously treated and relapsed clear cell renal carcinoma (ccRCC) patients

Annals of oncology, 2019-10, Vol.30, p.v384

2019

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952P - Results of phase I clinical trial of high doses of seleno-l-methionine (SLM) in sequential combination with axitinib in previously treated and relapsed clear cell renal carcinoma (ccRCC) patients

Annals of oncology, 2019-10, Vol.30, p.v384-v384

2019

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952PResults of phase I clinical trial of high doses of seleno-l-methionine (SLM) in sequential combination with axitinib in previously treated and relapsed clear cell renal carcinoma (ccRCC) patients

Annals of oncology, 2019-10, Vol.30 (Supplement_5)

2019

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Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines

British journal of cancer, 1999-12, Vol.81 (8), p.1304-1310

1999

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A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma

Journal of clinical oncology, 1987-10, Vol.5 (10), p.1559-1565

1987

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DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells

Cancer research (Chicago, Ill.), 1996-10, Vol.56 (20), p.4715-4723

1996

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Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models

Irinotecan in the Treatment of Colorectal Cancer: Clinical Overview

Synergistic antitumor activity of irinotecan in combination with 5-fluorouracil in rats bearing advanced colorectal cancer : Role of drug sequence and dose

Thymidylate synthase inhibitors in cancer therapy: direct and indirect inhibitors

Capecitabine and irinotecan as first-line chemotherapy in patients with metastatic colorectal cancer: results of an extended phase I study

Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1α expression, resulting in reduced angiogenesis

Randomized Double-Blind, Placebo-Controlled, Multicenter Phase 2 Trial of Selenomethionine as a Modulator of Efficacy and Toxicity of Chemoradiation in Locally-Advanced Squamous Cell Carcinoma of the Head and Neck

Concurrent Carboplatin, Paclitaxel, and Selenomethionine in Combination With Radiation for Patients With Unresectable Stage III Non-Small Cell Lung Cancer: A Phase 2 Multicenter Trial

Modeling of the time-dependency of in vitro drug cytotoxicity and resistance

Comparative antitumor efficacy of docetaxel and paclitaxel in nude mice bearing human tumor xenografts that overexpress the multidrug resistance protein (MRP)

Comparison of 5-fluoro-2′-deoxyuridine with 5-fluorouracil and their role in the treatment of colorectal cancer

Phase I Study of a Weekly Schedule of Irinotecan, High-Dose Leucovorin, and Infusional Fluorouracil as First-Line Chemotherapy in Patients With Advanced Colorectal Cancer

MDR1 P-glycoprotein is expressed by endothelial cells of newly formed capillaries in human gliomas but is not expressed in the neovasculature of other primary tumors

A phase I study of capecitabine and a modulatory dose of irinotecan in metastatic breast cancer

5-Ethynyluracil (776C85) : modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma

Interleukin 15 offers selective protection from irinotecan-induced intestinal toxicity in a preclinical animal model

Overexpression of Bax Enhances Antitumor Activity of Chemotherapeutic Agents in Human Head and Neck Squamous Cell Carcinoma

d,l-buthionine-(S,R)-sulfoximine potentiates in vivo the therapeutic efficacy of doxorubicin against multidrug resistance protein-expressing tumors

S-phase modulation by irinotecan : pilot studies in advanced solid tumors

Results of phase I clinical trial of high doses of seleno-l-methionine (SLM) in sequential combination with axitinib in previously treated and relapsed clear cell renal carcinoma (ccRCC) patients

952P - Results of phase I clinical trial of high doses of seleno-l-methionine (SLM) in sequential combination with axitinib in previously treated and relapsed clear cell renal carcinoma (ccRCC) patients

952PResults of phase I clinical trial of high doses of seleno-l-methionine (SLM) in sequential combination with axitinib in previously treated and relapsed clear cell renal carcinoma (ccRCC) patients

Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines

A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma

DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells

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